BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 19179305)

  • 1. Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice.
    Kuo YH; Zaidi SK; Gornostaeva S; Komori T; Stein GS; Castilla LH
    Blood; 2009 Apr; 113(14):3323-32. PubMed ID: 19179305
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.
    Zhen T; Cao Y; Ren G; Zhao L; Hyde RK; Lopez G; Feng D; Alemu L; Zhao K; Liu PP
    Blood; 2020 Nov; 136(21):2373-2385. PubMed ID: 32929473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.
    Miller JD; Stacy T; Liu PP; Speck NA
    Blood; 2001 Apr; 97(8):2248-56. PubMed ID: 11290585
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia.
    Richter LE; Wang Y; Becker ME; Coburn RA; Williams JT; Amador C; Hyde RK
    Mol Cancer Res; 2019 Jun; 17(6):1241-1252. PubMed ID: 30814129
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cbfbeta reduces Cbfbeta-SMMHC-associated acute myeloid leukemia in mice.
    Heilman SA; Kuo YH; Goudswaard CS; Valk PJ; Castilla LH
    Cancer Res; 2006 Dec; 66(23):11214-8. PubMed ID: 17145866
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11.
    Kundu M; Chen A; Anderson S; Kirby M; Xu L; Castilla LH; Bodine D; Liu PP
    Blood; 2002 Oct; 100(7):2449-56. PubMed ID: 12239155
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia.
    Kim HG; Kojima K; Swindle CS; Cotta CV; Huo Y; Reddy V; Klug CA
    Blood; 2008 Feb; 111(3):1567-74. PubMed ID: 17967943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates.
    Adya N; Stacy T; Speck NA; Liu PP
    Mol Cell Biol; 1998 Dec; 18(12):7432-43. PubMed ID: 9819429
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.
    Xue L; Pulikkan JA; Valk PJ; Castilla LH
    Blood; 2014 Jul; 124(3):426-36. PubMed ID: 24894773
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multimerization via its myosin domain facilitates nuclear localization and inhibition of core binding factor (CBF) activities by the CBFbeta-smooth muscle myosin heavy chain myeloid leukemia oncoprotein.
    Kummalue T; Lou J; Friedman AD
    Mol Cell Biol; 2002 Dec; 22(23):8278-91. PubMed ID: 12417730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.
    Castilla LH; Bushweller JH
    Adv Exp Med Biol; 2017; 962():229-244. PubMed ID: 28299661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The core binding factor (CBF) alpha interaction domain and the smooth muscle myosin heavy chain (SMMHC) segment of CBFbeta-SMMHC are both required to slow cell proliferation.
    Cao W; Adya N; Britos-Bray M; Liu PP; Friedman AD
    J Biol Chem; 1998 Nov; 273(47):31534-40. PubMed ID: 9813068
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis.
    Kamikubo Y; Hyde RK; Zhao L; Alemu L; Rivas C; Garrett LJ; Liu PP
    Blood; 2013 Jan; 121(4):638-42. PubMed ID: 23152542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.
    Hyde RK; Zhao L; Alemu L; Liu PP
    Leukemia; 2015 Aug; 29(8):1771-8. PubMed ID: 25742748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. c-Myc overcomes cell cycle inhibition by CBFbeta-SMMHC, a myeloid leukemia oncoprotein.
    Bernardin F; Yang Y; Civin CI; Friedman AD
    Cancer Biol Ther; 2002; 1(5):492-6. PubMed ID: 12496475
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development.
    Kuo YH; Gerstein RM; Castilla LH
    Blood; 2008 Feb; 111(3):1543-51. PubMed ID: 17940206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.
    Pulikkan JA; Hegde M; Ahmad HM; Belaghzal H; Illendula A; Yu J; O'Hagan K; Ou J; Muller-Tidow C; Wolfe SA; Zhu LJ; Dekker J; Bushweller JH; Castilla LH
    Cell; 2018 Jun; 174(1):172-186.e21. PubMed ID: 29958106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins.
    Lou J; Cao W; Bernardin F; Ayyanathan K; RauscherIII FJ; Friedman AD
    Oncogene; 2000 May; 19(22):2695-703. PubMed ID: 10851069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.
    Zhao X; Chen A; Yan X; Zhang Y; He F; Hayashi Y; Dong Y; Rao Y; Li B; Conway RM; Maiques-Diaz A; Elf SE; Huang N; Zuber J; Xiao Z; Tse W; Tenen DG; Wang Q; Chen W; Mulloy JC; Nimer SD; Huang G
    Blood; 2014 Mar; 123(11):1729-38. PubMed ID: 24449215
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CBFbeta-SMMHC slows proliferation of primary murine and human myeloid progenitors.
    D'Costa J; Chaudhuri S; Civin CI; Friedman AD
    Leukemia; 2005 Jun; 19(6):921-9. PubMed ID: 15815715
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.