86 related articles for article (PubMed ID: 19194827)
1. Combined inhibition of MEK and mTOR signaling inhibits initiation and progression of colorectal cancer.
Zhang YJ; Tian XQ; Sun DF; Zhao SL; Xiong H; Fang JY
Cancer Invest; 2009 Mar; 27(3):273-85. PubMed ID: 19194827
[TBL] [Abstract][Full Text] [Related]
2. Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer.
Zhang YJ; Zhao SL; Tian XQ; Sun DF; Xiong H; Dai Q; Li XQ; Fang JY
Int J Colorectal Dis; 2009 Jun; 24(6):629-39. PubMed ID: 19229543
[TBL] [Abstract][Full Text] [Related]
3. Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
Lasithiotakis KG; Sinnberg TW; Schittek B; Flaherty KT; Kulms D; Maczey E; Garbe C; Meier FE
J Invest Dermatol; 2008 Aug; 128(8):2013-23. PubMed ID: 18323781
[TBL] [Abstract][Full Text] [Related]
4. [Synergistic effect of rapamycin (RPM) and PD98059 on cell cycle and mTOR signal transduction in human colorectal cancer cells].
Zhang YJ; Fang JY; Sun DF; Zhao SL; Shen GF; Zheng Q; Zhu HY
Zhonghua Zhong Liu Za Zhi; 2007 Dec; 29(12):889-93. PubMed ID: 18478925
[TBL] [Abstract][Full Text] [Related]
5. The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.
Zhao H; Cui K; Nie F; Wang L; Brandl MB; Jin G; Li F; Mao Y; Xue Z; Rodriguez A; Chang J; Wong ST
Breast Cancer Res Treat; 2012 Jan; 131(2):425-36. PubMed ID: 21394501
[TBL] [Abstract][Full Text] [Related]
6. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
Martinelli E; Troiani T; D'Aiuto E; Morgillo F; Vitagliano D; Capasso A; Costantino S; Ciuffreda LP; Merolla F; Vecchione L; De Vriendt V; Tejpar S; Nappi A; Sforza V; Martini G; Berrino L; De Palma R; Ciardiello F
Int J Cancer; 2013 Nov; 133(9):2089-101. PubMed ID: 23629727
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Migliardi G; Sassi F; Torti D; Galimi F; Zanella ER; Buscarino M; Ribero D; Muratore A; Massucco P; Pisacane A; Risio M; Capussotti L; Marsoni S; Di Nicolantonio F; Bardelli A; Comoglio PM; Trusolino L; Bertotti A
Clin Cancer Res; 2012 May; 18(9):2515-25. PubMed ID: 22392911
[TBL] [Abstract][Full Text] [Related]
8. Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells.
Horie R; Nakamura O; Yamagami Y; Mori M; Nishimura H; Fukuoka N; Yamamoto T
Int J Oncol; 2016 Jan; 48(1):37-44. PubMed ID: 26530936
[TBL] [Abstract][Full Text] [Related]
9. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
deGraffenried LA; Friedrichs WE; Russell DH; Donzis EJ; Middleton AK; Silva JM; Roth RA; Hidalgo M
Clin Cancer Res; 2004 Dec; 10(23):8059-67. PubMed ID: 15585641
[TBL] [Abstract][Full Text] [Related]
11. Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers.
Temraz S; Mukherji D; Shamseddine A
Int J Mol Sci; 2015 Sep; 16(9):22976-88. PubMed ID: 26404261
[TBL] [Abstract][Full Text] [Related]
12. A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells.
D'Angelo L; Piazzi G; Pacilli A; Prossomariti A; Fazio C; Montanaro L; Graziani G; Fogliano V; Munarini A; Bianchi F; Belluzzi A; Bazzoli F; Ricciardiello L
Carcinogenesis; 2014 Oct; 35(10):2314-20. PubMed ID: 25123131
[TBL] [Abstract][Full Text] [Related]
13. Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation.
Paternot S; Roger PP
Cancer Res; 2009 Jun; 69(11):4577-81. PubMed ID: 19458076
[TBL] [Abstract][Full Text] [Related]
14. LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms.
Kristof AS; Pacheco-Rodriguez G; Schremmer B; Moss J
J Pharmacol Exp Ther; 2005 Sep; 314(3):1134-43. PubMed ID: 15923340
[TBL] [Abstract][Full Text] [Related]
15. Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model.
Mi R; Ma J; Zhang D; Li L; Zhang H
J Genet Genomics; 2009 Jun; 36(6):355-61. PubMed ID: 19539245
[TBL] [Abstract][Full Text] [Related]
16. mTOR signaling pathway is a target for the treatment of colorectal cancer.
Zhang YJ; Dai Q; Sun DF; Xiong H; Tian XQ; Gao FH; Xu MH; Chen GQ; Han ZG; Fang JY
Ann Surg Oncol; 2009 Sep; 16(9):2617-28. PubMed ID: 19517193
[TBL] [Abstract][Full Text] [Related]
17. Significance of mTOR signaling and its inhibitor against cancer stem-like cells in colorectal cancer.
Cai Z; Ke J; He X; Yuan R; Chen Y; Wu X; Wang L; Wang J; Lan P; Wu X
Ann Surg Oncol; 2014 Jan; 21(1):179-88. PubMed ID: 23907312
[TBL] [Abstract][Full Text] [Related]
18. Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines.
Maeda N; Fu W; Ortin A; de las Heras M; Fan H
J Virol; 2005 Apr; 79(7):4440-50. PubMed ID: 15767444
[TBL] [Abstract][Full Text] [Related]
19. Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.
Xu C; Zhang H; Liu C; Zhu Y; Wang X; Gao W; Huang S; Chen L
Oncotarget; 2015 Aug; 6(25):21452-67. PubMed ID: 26046303
[TBL] [Abstract][Full Text] [Related]
20. Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma.
Yang C; Zhang Y; Zhang Y; Zhang Z; Peng J; Li Z; Han L; You Q; Chen X; Rao X; Zhu Y; Liao Z
Int J Oncol; 2015 Sep; 47(3):909-17. PubMed ID: 26202311
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]