BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1038 related articles for article (PubMed ID: 19196846)

  • 1. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans.
    Lang D; Freudenberger C; Weinz C
    Drug Metab Dispos; 2009 May; 37(5):1046-55. PubMed ID: 19196846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans.
    Weinz C; Schwarz T; Kubitza D; Mueck W; Lang D
    Drug Metab Dispos; 2009 May; 37(5):1056-64. PubMed ID: 19196845
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.
    Erve JC; Vashishtha SC; DeMaio W; Talaat RE
    Drug Metab Dispos; 2007 Jun; 35(6):908-16. PubMed ID: 17353349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization.
    Li C; Chauret N; Trimble LA; Nicoll-Griffith DA; Silva JM; MacDonald D; Perrier H; Yergey JA; Parton T; Alexander RP; Warrellow GJ
    Drug Metab Dispos; 2001 Mar; 29(3):232-41. PubMed ID: 11181489
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison and metabolite identification.
    Kumar GN; Jayanti V; Lee RD; Whittern DN; Uchic J; Thomas S; Johnson P; Grabowski B; Sham H; Betebenner D; Kempf DJ; Denissen JF
    Drug Metab Dispos; 1999 Jan; 27(1):86-91. PubMed ID: 9884314
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560.
    Bateman KP; Trimble L; Chauret N; Silva J; Day S; Macdonald D; Dube D; Gallant M; Mastracchio A; Perrier H; Girard Y; Nicoll-Griffith D
    J Mass Spectrom; 2006 Jun; 41(6):771-80. PubMed ID: 16705670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes.
    Aprile S; Del Grosso E; Tron GC; Grosa G
    Drug Metab Dispos; 2007 Dec; 35(12):2252-61. PubMed ID: 17890446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biotransformation of tolterodine, a new muscarinic receptor antagonist, in mice, rats, and dogs.
    Andersson SH; Lindgren A; Postlind H
    Drug Metab Dispos; 1998 Jun; 26(6):528-35. PubMed ID: 9616187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
    Prakash C; Wang W; O'Connell T; Johnson KA
    Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro metabolism of rivoglitazone, a novel peroxisome proliferator-activated receptor γ agonist, in rat, monkey, and human liver microsomes and freshly isolated hepatocytes.
    Uchiyama M; Koda H; Fischer T; Mueller J; Yamamura N; Oguchi M; Iwabuchi H; Okazaki O; Izumi T
    Drug Metab Dispos; 2011 Jul; 39(7):1311-9. PubMed ID: 21511943
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of genistein metabolism in rats and humans using liver microsomes and hepatocytes.
    Bursztyka J; Perdu E; Tulliez J; Debrauwer L; Delous G; Canlet C; De Sousa G; Rahmani R; Benfenati E; Cravedi JP
    Food Chem Toxicol; 2008 Mar; 46(3):939-48. PubMed ID: 18063284
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans.
    Zhang D; He K; Raghavan N; Wang L; Mitroka J; Maxwell BD; Knabb RM; Frost C; Schuster A; Hao F; Gu Z; Humphreys WG; Grossman SJ
    Drug Metab Dispos; 2009 Aug; 37(8):1738-48. PubMed ID: 19420130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes.
    Lavrijsen K; van Houdt J; van Dyck D; Hendrickx J; Bockx M; Hurkmans R; Meuldermans W; Le Jeune L; Lauwers W; Heykants J
    Xenobiotica; 1992 Jul; 22(7):815-36. PubMed ID: 1455902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.
    Dean BJ; Chang S; Silva Elipe MV; Xia YQ; Braun M; Soli E; Zhao Y; Franklin RB; Karanam B
    Drug Metab Dispos; 2007 Feb; 35(2):283-92. PubMed ID: 17132765
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Species differences in the elimination of a peroxisome proliferator-activated receptor agonist highlighted by oxidative metabolism of its acyl glucuronide.
    Kochansky CJ; Xia YQ; Wang S; Cato B; Creighton M; Vincent SH; Franklin RB; Reed JR
    Drug Metab Dispos; 2005 Dec; 33(12):1894-904. PubMed ID: 16183782
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): identification of an unusual N-acetylglucosamine conjugate in the cynomolgus monkey.
    Johnson BM; Kamath AV; Leet JE; Liu X; Bhide RS; Tejwani RW; Zhang Y; Qian L; Wei DD; Lombardo LJ; Shu YZ
    Drug Metab Dispos; 2008 Dec; 36(12):2475-83. PubMed ID: 18787055
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro and in vivo metabolism of desogestrel in several species.
    Verhoeven CH; Krebbers SF; Wagenaars GN; Vos RM
    Drug Metab Dispos; 1998 Sep; 26(9):927-36. PubMed ID: 9733673
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Determination of rivaroxaban--a novel, oral, direct Factor Xa inhibitor--in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
    Rohde G
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Sep; 872(1-2):43-50. PubMed ID: 18675600
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
    Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of temelastine (SK&F 93944) in hepatocytes from rat, dog, cynomolgus monkey and man.
    Oldham HG; Standring P; Norman SJ; Blake TJ; Beattie I; Cox PJ; Chenery RJ
    Drug Metab Dispos; 1990; 18(2):146-52. PubMed ID: 1971564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 52.