BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

88 related articles for article (PubMed ID: 19197145)

  • 1. Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid.
    Jiang W; Deng W; Bailey SK; Nail CD; Frost AR; Brouillette WJ; Muccio DD; Grubbs CJ; Ruppert JM; Lobo-Ruppert SM
    Cancer Biol Ther; 2009 Feb; 8(3):289-98. PubMed ID: 19197145
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Randomized, Placebo-Controlled, Double-Blind, Dose Escalation, Single Dose, and Steady-State Pharmacokinetic Study of 9cUAB30 in Healthy Volunteers.
    Kolesar JM; Andrews S; Green H; Havighurst TC; Wollmer BW; DeShong K; Laux DE; Krontiras H; Muccio DD; Kim K; Grubbs CJ; House MG; Parnes HL; Heckman-Stoddard BM; Bailey HH
    Cancer Prev Res (Phila); 2019 Dec; 12(12):903-912. PubMed ID: 31484659
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis.
    Chou CF; Hsieh YH; Grubbs CJ; Atigadda VR; Mobley JA; Dummer R; Muccio DD; Eto I; Elmets CA; Garvey WT; Chang PL
    J Dermatol Sci; 2018 Jun; 90(3):343-356. PubMed ID: 29599065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptomic Analysis Shows Decreased Cortical Expression of NR4A1, NR4A2 and RXRB in Schizophrenia and Provides Evidence for Nuclear Receptor Dysregulation.
    Corley SM; Tsai SY; Wilkins MR; Shannon Weickert C
    PLoS One; 2016; 11(12):e0166944. PubMed ID: 27992436
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention.
    Muccio DD; Atigadda VR; Brouillette WJ; Bland KI; Krontiras H; Grubbs CJ
    Curr Top Med Chem; 2017; 17(6):676-695. PubMed ID: 27320329
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis.
    Wu L; Chaudhary SC; Atigadda VR; Belyaeva OV; Harville SR; Elmets CA; Muccio DD; Athar M; Kedishvili NY
    PLoS One; 2016; 11(4):e0153556. PubMed ID: 27078158
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preclinical Evaluation of UAB30 in Pediatric Renal and Hepatic Malignancies.
    Waters AM; Stewart JE; Atigadda VR; Mroczek-Musulman E; Muccio DD; Grubbs CJ; Beierle EA
    Mol Cancer Ther; 2016 May; 15(5):911-21. PubMed ID: 26873726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
    Atigadda VR; Xia G; Deshpande A; Wu L; Kedishvili N; Smith CD; Krontiras H; Bland KI; Grubbs CJ; Brouillette WJ; Muccio DD
    J Med Chem; 2015 Oct; 58(19):7763-74. PubMed ID: 26331194
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Augmented miR-10b expression associated with depressed expression of its target gene KLF4 involved in gastric carcinoma.
    Ma Z; Chen Y; Min L; Li L; Huang H; Li J; Yan Q; Song P; Dai L; Yao X
    Int J Clin Exp Pathol; 2015; 8(5):5071-9. PubMed ID: 26191201
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma.
    Waters AM; Stewart JE; Atigadda VR; Mroczek-Musulman E; Muccio DD; Grubbs CJ; Beierle EA
    Mol Cancer Ther; 2015 Jul; 14(7):1559-69. PubMed ID: 25944918
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity.
    Atigadda VR; Xia G; Desphande A; Boerma LJ; Lobo-Ruppert S; Grubbs CJ; Smith CD; Brouillette WJ; Muccio DD
    J Med Chem; 2014 Jun; 57(12):5370-80. PubMed ID: 24801499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
    Desphande A; Xia G; Boerma LJ; Vines KK; Atigadda VR; Lobo-Ruppert S; Grubbs CJ; Moeinpour FL; Smith CD; Christov K; Brouillette WJ; Muccio DD
    Bioorg Med Chem; 2014 Jan; 22(1):178-85. PubMed ID: 24359708
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defining the communication between agonist and coactivator binding in the retinoid X receptor α ligand binding domain.
    Boerma LJ; Xia G; Qui C; Cox BD; Chalmers MJ; Smith CD; Lobo-Ruppert S; Griffin PR; Muccio DD; Renfrow MB
    J Biol Chem; 2014 Jan; 289(2):814-26. PubMed ID: 24187139
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear hormone receptor functions in keratinocyte and melanocyte homeostasis, epidermal carcinogenesis and melanomagenesis.
    Hyter S; Indra AK
    FEBS Lett; 2013 Mar; 587(6):529-41. PubMed ID: 23395795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The retinoid X receptors and their ligands.
    Dawson MI; Xia Z
    Biochim Biophys Acta; 2012 Jan; 1821(1):21-56. PubMed ID: 22020178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A KLF4-miRNA-206 autoregulatory feedback loop can promote or inhibit protein translation depending upon cell context.
    Lin CC; Liu LZ; Addison JB; Wonderlin WF; Ivanov AV; Ruppert JM
    Mol Cell Biol; 2011 Jun; 31(12):2513-27. PubMed ID: 21518959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A pilot, first-in-human, pharmacokinetic study of 9cUAB30 in healthy volunteers.
    Kolesar JM; Hoel R; Pomplun M; Havighurst T; Stublaski J; Wollmer B; Krontiras H; Brouillette W; Muccio D; Kim K; Grubbs CJ; Bailey HE
    Cancer Prev Res (Phila); 2010 Dec; 3(12):1565-70. PubMed ID: 21149332
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mammalian Krüppel-like factors in health and diseases.
    McConnell BB; Yang VW
    Physiol Rev; 2010 Oct; 90(4):1337-81. PubMed ID: 20959618
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Retinoid pathway and cancer therapeutics.
    Bushue N; Wan YJ
    Adv Drug Deliv Rev; 2010 Oct; 62(13):1285-98. PubMed ID: 20654663
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis.
    Bureau C; Hanoun N; Torrisani J; Vinel JP; Buscail L; Cordelier P
    Curr Genomics; 2009 Aug; 10(5):353-60. PubMed ID: 20119532
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.