These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 19198628)

  • 1. Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin.
    Scholl FA; Dumesic PA; Barragan DI; Charron J; Khavari PA
    Oncogene; 2009 Mar; 28(12):1485-95. PubMed ID: 19198628
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia.
    Scholl FA; Dumesic PA; Barragan DI; Harada K; Bissonauth V; Charron J; Khavari PA
    Dev Cell; 2007 Apr; 12(4):615-29. PubMed ID: 17419998
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors.
    Zhang J; Lodish HF
    Blood; 2004 Sep; 104(6):1679-87. PubMed ID: 15166036
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
    Scholl FA; Dumesic PA; Barragan DI; Harada K; Charron J; Khavari PA
    Cancer Res; 2009 May; 69(9):3772-8. PubMed ID: 19383924
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes.
    Brandt KJ; Carpintero R; Gruaz L; Molnarfi N; Burger D
    J Leukoc Biol; 2010 Dec; 88(6):1191-200. PubMed ID: 20837746
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
    Aoidi R; Maltais A; Charron J
    Sci Signal; 2016 Jan; 9(412):ra9. PubMed ID: 26814233
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
    Westermarck J; Li SP; Kallunki T; Han J; Kähäri VM
    Mol Cell Biol; 2001 Apr; 21(7):2373-83. PubMed ID: 11259586
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative regulation of mTOR activation by diacylglycerol kinases.
    Gorentla BK; Wan CK; Zhong XP
    Blood; 2011 Apr; 117(15):4022-31. PubMed ID: 21310925
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sef downregulation by Ras causes MEK1/2 to become aberrantly nuclear localized leading to polyploidy and neoplastic transformation.
    Duhamel S; Hébert J; Gaboury L; Bouchard A; Simon R; Sauter G; Basik M; Meloche S
    Cancer Res; 2012 Feb; 72(3):626-35. PubMed ID: 22298595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
    Okumura K; Shirasawa S; Nishioka M; Sasazuki T
    Cancer Res; 1999 May; 59(10):2445-50. PubMed ID: 10344756
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
    Gailhouste L; Ezan F; Bessard A; Frémin C; Rageul J; Langouët S; Baffet G
    Int J Cancer; 2010 Mar; 126(6):1367-77. PubMed ID: 19816936
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elastin peptides activate extracellular signal-regulated kinase 1/2 via a Ras-independent mechanism requiring both p110gamma/Raf-1 and protein kinase A/B-Raf signaling in human skin fibroblasts.
    Duca L; Lambert E; Debret R; Rothhut B; Blanchevoye C; Delacoux F; Hornebeck W; Martiny L; Debelle L
    Mol Pharmacol; 2005 Apr; 67(4):1315-24. PubMed ID: 15653554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
    Leelawat K; Leelawat S; Narong S; Hongeng S
    World J Gastroenterol; 2007 Mar; 13(10):1561-8. PubMed ID: 17461449
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MEK1/2 dual-specificity protein kinases: structure and regulation.
    Roskoski R
    Biochem Biophys Res Commun; 2012 Jan; 417(1):5-10. PubMed ID: 22177953
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mek1 alters epidermal growth and differentiation.
    Scholl FA; Dumesic PA; Khavari PA
    Cancer Res; 2004 Sep; 64(17):6035-40. PubMed ID: 15342384
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platelet factor 4 inhibits FGF2-induced endothelial cell proliferation via the extracellular signal-regulated kinase pathway but not by the phosphatidylinositol 3-kinase pathway.
    Sulpice E; Bryckaert M; Lacour J; Contreres JO; Tobelem G
    Blood; 2002 Nov; 100(9):3087-94. PubMed ID: 12384403
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downstream effectors of oncogenic ras in multiple myeloma cells.
    Hu L; Shi Y; Hsu JH; Gera J; Van Ness B; Lichtenstein A
    Blood; 2003 Apr; 101(8):3126-35. PubMed ID: 12515720
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines.
    Maeda N; Fu W; Ortin A; de las Heras M; Fan H
    J Virol; 2005 Apr; 79(7):4440-50. PubMed ID: 15767444
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MEK1/2 overactivation can promote growth arrest by mediating ERK1/2-dependent phosphorylation of p70S6K.
    Guégan JP; Ezan F; Gailhouste L; Langouët S; Baffet G
    J Cell Physiol; 2014 Jul; 229(7):903-15. PubMed ID: 24501087
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
    Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
    BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.