BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 19204737)

  • 1. Influence of the G2677T/C3435T haplotype of MDR1 on P-glycoprotein trafficking and ibutilide-induced block of HERG.
    McBride BF; Yang T; Roden DM
    Pharmacogenomics J; 2009 Jun; 9(3):194-201. PubMed ID: 19204737
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children.
    Seven M; Batar B; Unal S; Yesil G; Yuksel A; Guven M
    Mol Biol Rep; 2014 Jan; 41(1):331-6. PubMed ID: 24213830
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1.
    Yang T; McBride BF; Leake BF; Kim RB; Roden DM
    Br J Pharmacol; 2010 Nov; 161(5):1023-33. PubMed ID: 20977453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide.
    Lin C; Ke X; Ranade V; Somberg J
    Cardiology; 2008; 110(3):209-16. PubMed ID: 18057887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of MDR1 haplotypes derived from C1236T, G2677T/A and C3435T on the pharmacokinetics of single-dose oral digoxin in healthy Chinese volunteers.
    Xu P; Jiang ZP; Zhang BK; Tu JY; Li HD
    Pharmacology; 2008; 82(3):221-7. PubMed ID: 18810246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.
    McBride BF; Yang T; Liu K; Urban TJ; Giacomini KM; Kim RB; Roden DM
    J Cardiovasc Pharmacol; 2009 Jul; 54(1):63-71. PubMed ID: 19528813
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High baseline serum total and LDL cholesterol levels are associated with MDR1 haplotypes in Brazilian hypercholesterolemic individuals of European descent.
    Rodrigues AC; Rebecchi IM; Bertolami MC; Faludi AA; Hirata MH; Hirata RD
    Braz J Med Biol Res; 2005 Sep; 38(9):1389-97. PubMed ID: 16138223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Frequency of G2677T/A and C3435T polymorphisms of MDR1 gene in preeclamptic women.
    Bogacz A; Mrozikiewicz PM; Deka-Pawlik D; Seremak-Mrozikiewicz A; Bartkowiak-Wieczorek J; Barlik M; Drews K; Kowalska A; Grześkowiak E
    Ginekol Pol; 2013 Sep; 84(9):781-7. PubMed ID: 24191517
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural determinants of HERG channel block by clofilium and ibutilide.
    Perry M; de Groot MJ; Helliwell R; Leishman D; Tristani-Firouzi M; Sanguinetti MC; Mitcheson J
    Mol Pharmacol; 2004 Aug; 66(2):240-9. PubMed ID: 15266014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Correlation between MDR1 methylation status in the promoter region and MDR1 genetic polymorphism in 194 healthy Chinese Han subjects.
    Jiang ZP; Xu P; Liu RR; Li HD; Wang GP; Zhao XL; Chen FP
    Pharmacogenomics; 2008 Dec; 9(12):1801-8. PubMed ID: 19072639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs.
    Perry M; Stansfeld PJ; Leaney J; Wood C; de Groot MJ; Leishman D; Sutcliffe MJ; Mitcheson JS
    Mol Pharmacol; 2006 Feb; 69(2):509-19. PubMed ID: 16291873
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug block of I(kr): model systems and relevance to human arrhythmias.
    Yang T; Snyders D; Roden DM
    J Cardiovasc Pharmacol; 2001 Nov; 38(5):737-44. PubMed ID: 11602820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Relationship between genetic polymorphism of multidrug resistance 1 gene and the risk of childhood acute lymphocytic leukemia].
    Lü H; Du ZZ; Wang W; Wang W; Zhao WL; Wang Y; Hu SY; Chai YH
    Zhonghua Er Ke Za Zhi; 2012 Sep; 50(9):692-6. PubMed ID: 23158821
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MDR1 genotypes do not influence the absorption of a single oral dose of 600 mg valacyclovir in healthy Chinese Han ethnic males.
    Zhang Y; Jiang XH; Hu YQ; Li ZR; Su L; Wang ZG; Ma G
    Br J Clin Pharmacol; 2008 Aug; 66(2):247-54. PubMed ID: 18460034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms.
    Hemauer SJ; Nanovskaya TN; Abdel-Rahman SZ; Patrikeeva SL; Hankins GD; Ahmed MS
    Biochem Pharmacol; 2010 Mar; 79(6):921-5. PubMed ID: 19896927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes.
    Oselin K; Gerloff T; Mrozikiewicz PM; Pähkla R; Roots I
    Fundam Clin Pharmacol; 2003 Aug; 17(4):463-9. PubMed ID: 12914549
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).
    Hitzl M; Schaeffeler E; Hocher B; Slowinski T; Halle H; Eichelbaum M; Kaufmann P; Fritz P; Fromm MF; Schwab M
    Pharmacogenetics; 2004 May; 14(5):309-18. PubMed ID: 15115917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Frequency of the C1236T, G2677T/A and C3435T MDR1 gene polymorphisms in the Serbian population.
    Milojkovic M; Stojnev S; Jovanovic I; Ljubisavljevic S; Stefanovic V; Sunder-Plassman R
    Pharmacol Rep; 2011; 63(3):808-14. PubMed ID: 21857092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
    Ficker E; Obejero-Paz CA; Zhao S; Brown AM
    J Biol Chem; 2002 Feb; 277(7):4989-98. PubMed ID: 11741928
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.
    Fung KL; Pan J; Ohnuma S; Lund PE; Pixley JN; Kimchi-Sarfaty C; Ambudkar SV; Gottesman MM
    Cancer Res; 2014 Jan; 74(2):598-608. PubMed ID: 24305879
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.