BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

826 related articles for article (PubMed ID: 19207427)

  • 1. Improvement of multivariate image analysis applied to quantitative structure-activity relationship (QSAR) analysis by using wavelet-principal component analysis ranking variable selection and least-squares support vector machine regression: QSAR study of checkpoint kinase WEE1 inhibitors.
    Cormanich RA; Goodarzi M; Freitas MP
    Chem Biol Drug Des; 2009 Feb; 73(2):244-52. PubMed ID: 19207427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3D-QSAR studies of Checkpoint Kinase Weel inhibitors based on molecular docking, CoMFA and CoMSIA.
    Yi P; Fang X; Qiu M
    Eur J Med Chem; 2008 May; 43(5):925-38. PubMed ID: 17698256
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Application of partial least squares and radial basis function neural networks in multivariate imaging analysis-quantitative structure activity relationship: study of cyclin dependent kinase 4 inhibitors.
    Saghaie L; Shahlaei M; Madadkar-Sobhani A; Fassihi A
    J Mol Graph Model; 2010 Dec; 29(4):518-28. PubMed ID: 21071247
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MIA-QSAR coupled to principal component analysis-adaptive neuro-fuzzy inference systems (PCA-ANFIS) for the modeling of the anti-HIV reverse transcriptase activities of TIBO derivatives.
    Goodarzi M; Freitas MP
    Eur J Med Chem; 2010 Apr; 45(4):1352-8. PubMed ID: 20060625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors.
    Wichapong K; Lindner M; Pianwanit S; Kokpol S; Sippl W
    Eur J Med Chem; 2009 Apr; 44(4):1383-95. PubMed ID: 18976834
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
    Smaill JB; Baker EN; Booth RJ; Bridges AJ; Dickson JM; Dobrusin EM; Ivanovic I; Kraker AJ; Lee HH; Lunney EA; Ortwine DF; Palmer BD; Quin J; Squire CJ; Thompson AM; Denny WA
    Eur J Med Chem; 2008 Jun; 43(6):1276-96. PubMed ID: 17869387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring QSAR for substituted 2-sulfonyl-phenyl-indol derivatives as potent and selective COX-2 inhibitors using different chemometrics tools.
    Khoshneviszadeh M; Edraki N; Miri R; Hemmateenejad B
    Chem Biol Drug Des; 2008 Dec; 72(6):564-74. PubMed ID: 19090923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 3D-QSAR CoMFA analysis of C5 substituted pyrrolotriazines as HER2 (ErbB2) inhibitors.
    Awale M; Mohan CG
    J Mol Graph Model; 2008 Apr; 26(7):1169-78. PubMed ID: 18055238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative structure-activity relationship modeling of dopamine D(1) antagonists using comparative molecular field analysis, genetic algorithms-partial least-squares, and K nearest neighbor methods.
    Hoffman B; Cho SJ; Zheng W; Wyrick S; Nichols DE; Mailman RB; Tropsha A
    J Med Chem; 1999 Aug; 42(17):3217-26. PubMed ID: 10464009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prediction of biological activity of Aurora-A kinase inhibitors by multilinear regression analysis and support vector machine.
    Yan A; Chong Y; Wang L; Hu X; Wang K
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2238-43. PubMed ID: 21421314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural requirements of pyrido[2,3-d]pyrimidin-7-one as CDK4/D inhibitors: 2D autocorrelation, CoMFA and CoMSIA analyses.
    Caballero J; Fernández M; González-Nilo FD
    Bioorg Med Chem; 2008 Jun; 16(11):6103-15. PubMed ID: 18468903
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Partial least squares modeling and genetic algorithm optimization in quantitative structure-activity relationships.
    Hasegawa K; Funatsu K
    SAR QSAR Environ Res; 2000; 11(3-4):189-209. PubMed ID: 10969871
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A three-dimensional quantitative structure-activity analysis of a new class of bisphenol topoisomerase IIalpha inhibitors.
    Liang H; Wu X; Yalowich JC; Hasinoff BB
    Mol Pharmacol; 2008 Mar; 73(3):686-96. PubMed ID: 18045852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prediction of anti-HIV-1 activity of a series of tetrapyrrole molecules.
    Vanyúr R; Héberger K; Jakus J
    J Chem Inf Comput Sci; 2003; 43(6):1829-36. PubMed ID: 14632429
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of fungicidal activities of rice blast disease based on least-squares support vector machines and project pursuit regression.
    Du H; Wang J; Hu Z; Yao X; Zhang X
    J Agric Food Chem; 2008 Nov; 56(22):10785-92. PubMed ID: 18950187
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multiple field three dimensional quantitative structure-activity relationship (MF-3D-QSAR).
    Du QS; Huang RB; Wei YT; Du LQ; Chou KC
    J Comput Chem; 2008 Jan; 29(2):211-9. PubMed ID: 17559075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacophore identification and validation study of CK2 inhibitors using CoMFA/CoMSIA.
    Morshed MN; Muddassar M; Pasha FA; Cho SJ
    Chem Biol Drug Des; 2009 Aug; 74(2):148-58. PubMed ID: 19563463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacophore-based 3D-QSAR of HIF-1 inhibitors.
    Chung JY; Pasha FA; Cho SJ; Won M; Lee JJ; Lee K
    Arch Pharm Res; 2009 Mar; 32(3):317-23. PubMed ID: 19387572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Retention prediction of peptides based on uninformative variable elimination by partial least squares.
    Put R; Daszykowski M; Baczek T; Vander Heyden Y
    J Proteome Res; 2006 Jul; 5(7):1618-25. PubMed ID: 16823969
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors.
    Marzaro G; Chilin A; Guiotto A; Uriarte E; Brun P; Castagliuolo I; Tonus F; González-Díaz H
    Eur J Med Chem; 2011 Jun; 46(6):2185-92. PubMed ID: 21447431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.