188 related articles for article (PubMed ID: 19209887)
1. LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species.
Li N; Palandra J; Nemirovskiy OV; Lai Y
Anal Chem; 2009 Mar; 81(6):2251-9. PubMed ID: 19209887
[TBL] [Abstract][Full Text] [Related]
2. Quantitative expression profile of hepatobiliary transporters in sandwich cultured rat and human hepatocytes.
Li N; Bi YA; Duignan DB; Lai Y
Mol Pharm; 2009; 6(4):1180-9. PubMed ID: 19545175
[TBL] [Abstract][Full Text] [Related]
3. Improved extrapolation of hepatobiliary clearance from in vitro sandwich cultured rat hepatocytes through absolute quantification of hepatobiliary transporters.
Li N; Singh P; Mandrell KM; Lai Y
Mol Pharm; 2010 Jun; 7(3):630-41. PubMed ID: 20438085
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse.
Zhang J; He K; Cai L; Chen YC; Yang Y; Shi Q; Woolf TF; Ge W; Guo L; Borlak J; Tong W
Chem Biol Interact; 2016 Aug; 255():45-54. PubMed ID: 27000539
[TBL] [Abstract][Full Text] [Related]
5. LC-MS/MS-based quantification of efflux transporter proteins at the BBB.
Gomez-Zepeda D; Taghi M; Smirnova M; Sergent P; Liu WQ; Chhuon C; Vidal M; Picard M; Thioulouse E; Broutin I; Guerrera IC; Scherrmann JM; Parmentier Y; Decleves X; Menet MC
J Pharm Biomed Anal; 2019 Feb; 164():496-508. PubMed ID: 30453156
[TBL] [Abstract][Full Text] [Related]
6. Interindividual variability in the hepatic expression of the human breast cancer resistance protein (BCRP/ABCG2): effect of age, sex, and genotype.
Prasad B; Lai Y; Lin Y; Unadkat JD
J Pharm Sci; 2013 Mar; 102(3):787-93. PubMed ID: 23280364
[TBL] [Abstract][Full Text] [Related]
7. In vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review.
Cheng Y; Woolf TF; Gan J; He K
Chem Biol Interact; 2016 Aug; 255():23-30. PubMed ID: 26683212
[TBL] [Abstract][Full Text] [Related]
8. Assessment of Bile Salt Export Pump (BSEP) Inhibition in Membrane Vesicles Using Radioactive and LC/MS-Based Detection Methods.
Marroquin LD; Bonin PD; Keefer J; Schroeter T
Curr Protoc Toxicol; 2017 Feb; 71():14.14.1-14.14.20. PubMed ID: 28146280
[TBL] [Abstract][Full Text] [Related]
9. Optimization of sample preparation for transporter protein quantification in tissues by LC-MS/MS.
Jankovskaja S; Kamiie J; Rezeli M; Gustavsson L; Sugihara Y; Miliotis T; Ruzgas T; Marko-Varga G
J Pharm Biomed Anal; 2019 Feb; 164():9-15. PubMed ID: 30339949
[TBL] [Abstract][Full Text] [Related]
10. Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.
Cheng Y; Freeden C; Zhang Y; Abraham P; Shen H; Wescott D; Humphreys WG; Gan J; Lai Y
Biopharm Drug Dispos; 2016 Jul; 37(5):276-86. PubMed ID: 27059119
[TBL] [Abstract][Full Text] [Related]
11. Absolute difference of hepatobiliary transporter multidrug resistance-associated protein (MRP2/Mrp2) in liver tissues and isolated hepatocytes from rat, dog, monkey, and human.
Li N; Zhang Y; Hua F; Lai Y
Drug Metab Dispos; 2009 Jan; 37(1):66-73. PubMed ID: 18832477
[TBL] [Abstract][Full Text] [Related]
12. Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.
Fallon JK; Smith PC; Xia CQ; Kim MS
Pharm Res; 2016 Sep; 33(9):2280-8. PubMed ID: 27356525
[TBL] [Abstract][Full Text] [Related]
13. Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Morgan RE; Trauner M; van Staden CJ; Lee PH; Ramachandran B; Eschenberg M; Afshari CA; Qualls CW; Lightfoot-Dunn R; Hamadeh HK
Toxicol Sci; 2010 Dec; 118(2):485-500. PubMed ID: 20829430
[TBL] [Abstract][Full Text] [Related]
14. Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: possible functional consequences.
Vander Borght S; Libbrecht L; Katoonizadeh A; van Pelt J; Cassiman D; Nevens F; Van Lommel A; Petersen BE; Fevery J; Jansen PL; Roskams TA
J Histochem Cytochem; 2006 Sep; 54(9):1051-9. PubMed ID: 16709727
[TBL] [Abstract][Full Text] [Related]
15. A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Morgan RE; van Staden CJ; Chen Y; Kalyanaraman N; Kalanzi J; Dunn RT; Afshari CA; Hamadeh HK
Toxicol Sci; 2013 Nov; 136(1):216-41. PubMed ID: 23956101
[TBL] [Abstract][Full Text] [Related]
16. Validation of uPA/SCID mouse with humanized liver as a human liver model: protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases by LC-MS/MS.
Ohtsuki S; Kawakami H; Inoue T; Nakamura K; Tateno C; Katsukura Y; Obuchi W; Uchida Y; Kamiie J; Horie T; Terasaki T
Drug Metab Dispos; 2014 Jun; 42(6):1039-43. PubMed ID: 24711249
[TBL] [Abstract][Full Text] [Related]
17. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
Ulvestad M; Nordell P; Asplund A; Rehnström M; Jacobsson S; Holmgren G; Davidson L; Brolén G; Edsbagge J; Björquist P; Küppers-Munther B; Andersson TB
Biochem Pharmacol; 2013 Sep; 86(5):691-702. PubMed ID: 23856292
[TBL] [Abstract][Full Text] [Related]
18. Comparison of LC-MS/MS-based targeted proteomics and conventional analytical methods for monitoring breast cancer resistance protein expression.
Li H; Meng F; Jiang L; Ren Y; Qiu Z; Yu P; Peng J
Life Sci; 2019 Aug; 231():116548. PubMed ID: 31181228
[TBL] [Abstract][Full Text] [Related]
19. Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics.
Wang L; Prasad B; Salphati L; Chu X; Gupta A; Hop CE; Evers R; Unadkat JD
Drug Metab Dispos; 2015 Mar; 43(3):367-74. PubMed ID: 25534768
[TBL] [Abstract][Full Text] [Related]
20. Lack of Interactions Between an Antisense Oligonucleotide with 2'-O-(2-Methoxyethyl) Modifications and Major Drug Transporters.
Yu RZ; Warren MS; Watanabe T; Nichols B; Jahic M; Huang J; Burkey J; Geary RS; Henry SP; Wang Y
Nucleic Acid Ther; 2016 Apr; 26(2):111-7. PubMed ID: 26959999
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
