65 related articles for article (PubMed ID: 19209893)
41. Structure-activity relationships of antitubercular nitroimidazoles. 1. Structural features associated with aerobic and anaerobic activities of 4- and 5-nitroimidazoles.
Kim P; Zhang L; Manjunatha UH; Singh R; Patel S; Jiricek J; Keller TH; Boshoff HI; Barry CE; Dowd CS
J Med Chem; 2009 Mar; 52(5):1317-28. PubMed ID: 19209889
[TBL] [Abstract][Full Text] [Related]
42. PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release.
Singh R; Manjunatha U; Boshoff HI; Ha YH; Niyomrattanakit P; Ledwidge R; Dowd CS; Lee IY; Kim P; Zhang L; Kang S; Keller TH; Jiricek J; Barry CE
Science; 2008 Nov; 322(5906):1392-5. PubMed ID: 19039139
[TBL] [Abstract][Full Text] [Related]
43. Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824.
Li X; Manjunatha UH; Goodwin MB; Knox JE; Lipinski CA; Keller TH; Barry CE; Dowd CS
Bioorg Med Chem Lett; 2008 Apr; 18(7):2256-62. PubMed ID: 18358721
[TBL] [Abstract][Full Text] [Related]
44. Multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis: epidemiology and control.
Matteelli A; Migliori GB; Cirillo D; Centis R; Girard E; Raviglion M
Expert Rev Anti Infect Ther; 2007 Oct; 5(5):857-71. PubMed ID: 17914919
[TBL] [Abstract][Full Text] [Related]
45. CAESAR: a new conformer generation algorithm based on recursive buildup and local rotational symmetry consideration.
Li J; Ehlers T; Sutter J; Varma-O'brien S; Kirchmair J
J Chem Inf Model; 2007; 47(5):1923-32. PubMed ID: 17691764
[TBL] [Abstract][Full Text] [Related]
46. New beta-alanine derivatives are orally available glucagon receptor antagonists.
Lau J; Behrens C; Sidelmann UG; Knudsen LB; Lundt B; Sams C; Ynddal L; Brand CL; Pridal L; Ling A; Kiel D; Plewe M; Shi S; Madsen P
J Med Chem; 2007 Jan; 50(1):113-28. PubMed ID: 17201415
[TBL] [Abstract][Full Text] [Related]
47. OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Matsumoto M; Hashizume H; Tomishige T; Kawasaki M; Tsubouchi H; Sasaki H; Shimokawa Y; Komatsu M
PLoS Med; 2006 Nov; 3(11):e466. PubMed ID: 17132069
[TBL] [Abstract][Full Text] [Related]
48. Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone.
Padayatti PS; Sheri A; Totir MA; Helfand MS; Carey MP; Anderson VE; Carey PR; Bethel CR; Bonomo RA; Buynak JD; van den Akker F
J Am Chem Soc; 2006 Oct; 128(40):13235-42. PubMed ID: 17017804
[TBL] [Abstract][Full Text] [Related]
49. Asymmetric, anti-selective scandium-catalyzed Sakurai additions to glyoxyamide. Applications to the syntheses of N-boc D-alloisoleucine and D-isoleucine.
Evans DA; Aye Y; Wu J
Org Lett; 2006 May; 8(10):2071-3. PubMed ID: 16671784
[TBL] [Abstract][Full Text] [Related]
50. Dihydropyrrolopyrazole transforming growth factor-beta type I receptor kinase domain inhibitors: a novel benzimidazole series with selectivity versus transforming growth factor-beta type II receptor kinase and mixed lineage kinase-7.
Li HY; Wang Y; Heap CR; King CH; Mundla SR; Voss M; Clawson DK; Yan L; Campbell RM; Anderson BD; Wagner JR; Britt K; Lu KX; McMillen WT; Yingling JM
J Med Chem; 2006 Mar; 49(6):2138-42. PubMed ID: 16539403
[TBL] [Abstract][Full Text] [Related]
51. Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis.
Manjunatha UH; Boshoff H; Dowd CS; Zhang L; Albert TJ; Norton JE; Daniels L; Dick T; Pang SS; Barry CE
Proc Natl Acad Sci U S A; 2006 Jan; 103(2):431-6. PubMed ID: 16387854
[TBL] [Abstract][Full Text] [Related]
52. Synthesis, structure-activity relationships, and biological properties of 1-heteroaryl-4-[omega-(1H-indol-3-yl)alkyl]piperazines, novel potential antipsychotics combining potent dopamine D2 receptor antagonism with potent serotonin reuptake inhibition.
Smid P; Coolen HK; Keizer HG; van Hes R; de Moes JP; den Hartog AP; Stork B; Plekkenpol RH; Niemann LC; Stroomer CN; Tulp MT; van Stuivenberg HH; McCreary AC; Hesselink MB; Herremans AH; Kruse CG
J Med Chem; 2005 Nov; 48(22):6855-69. PubMed ID: 16250644
[TBL] [Abstract][Full Text] [Related]
53. Efficient stereochemical controllers in biaryl Suzuki coupling reactions: benzylic carbinols bearing in beta-position thioether, dimethylamino, or sulfoxide groups.
Broutin PE; Colobert F
Org Lett; 2005 Aug; 7(17):3737-40. PubMed ID: 16092863
[TBL] [Abstract][Full Text] [Related]
54. Synthesis of (-)-tetrodotoxin: preparation of an advanced cyclohexenone intermediate.
Taber DF; Storck PH
J Org Chem; 2003 Oct; 68(20):7768-71. PubMed ID: 14510553
[TBL] [Abstract][Full Text] [Related]
55. First asymmetric total synthesis of tetrodotoxin.
Ohyabu N; Nishikawa T; Isobe M
J Am Chem Soc; 2003 Jul; 125(29):8798-805. PubMed ID: 12862474
[TBL] [Abstract][Full Text] [Related]
56. Total synthesis of apratoxin A.
Chen J; Forsyth CJ
J Am Chem Soc; 2003 Jul; 125(29):8734-5. PubMed ID: 12862462
[TBL] [Abstract][Full Text] [Related]
57. Large-scale production of coenzyme F420-5,6 by using Mycobacterium smegmatis.
Isabelle D; Simpson DR; Daniels L
Appl Environ Microbiol; 2002 Nov; 68(11):5750-5. PubMed ID: 12406775
[TBL] [Abstract][Full Text] [Related]
58. C-H activation and palladium migration within Biaryls under Heck reaction conditions.
Karig G; Moon MT; Thasana N; Gallagher T
Org Lett; 2002 Sep; 4(18):3115-8. PubMed ID: 12201730
[TBL] [Abstract][Full Text] [Related]
59. A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis.
Stover CK; Warrener P; VanDevanter DR; Sherman DR; Arain TM; Langhorne MH; Anderson SW; Towell JA; Yuan Y; McMurray DN; Kreiswirth BN; Barry CE; Baker WR
Nature; 2000 Jun; 405(6789):962-6. PubMed ID: 10879539
[TBL] [Abstract][Full Text] [Related]
60. Hypoxia-selective antitumor agents. 10. bis(nitroimidazoles) and related Bis(nitroheterocycles): development of derivatives with higher rates of metabolic activation under hypoxia and improved aqueous solubility.
Hay MP; Lee HH; Wilson WR; Roberts PB; Denny WA
J Med Chem; 1995 May; 38(11):1928-41. PubMed ID: 7783125
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
