BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 19211248)

  • 1. Synthesis and biological evaluation of cis-locked vinylogous combretastatin-A4 analogues: derivatives with a cyclopropyl-vinyl or a cyclopropyl-amide bridge.
    Ty N; Kaffy J; Arrault A; Thoret S; Pontikis R; Dubois J; Morin-Allory L; Florent JC
    Bioorg Med Chem Lett; 2009 Mar; 19(5):1318-22. PubMed ID: 19211248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation.
    Li YW; Liu J; Liu N; Shi D; Zhou XT; Lv JG; Zhu J; Zheng CH; Zhou YJ
    Bioorg Med Chem; 2011 Jun; 19(11):3579-84. PubMed ID: 21536450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4.
    Ty N; Pontikis R; Chabot GG; Devillers E; Quentin L; Bourg S; Florent JC
    Bioorg Med Chem; 2013 Mar; 21(5):1357-66. PubMed ID: 23369686
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation.
    Kaffy J; Pontikis R; Carrez D; Croisy A; Monneret C; Florent JC
    Bioorg Med Chem; 2006 Jun; 14(12):4067-77. PubMed ID: 16510288
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and antitumor-evaluation of cyclopropyl-containing combretastatin analogs.
    Fürst R; Zupkó I; Berényi A; Ecker GF; Rinner U
    Bioorg Med Chem Lett; 2009 Dec; 19(24):6948-51. PubMed ID: 19879758
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives.
    Kaffy J; Pontikis R; Florent JC; Monneret C
    Org Biomol Chem; 2005 Jul; 3(14):2657-60. PubMed ID: 15999202
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation.
    Borrel C; Thoret S; Cachet X; Guénard D; Tillequin F; Koch M; Michel S
    Bioorg Med Chem; 2005 Jun; 13(11):3853-64. PubMed ID: 15863010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
    O'Boyle NM; Carr M; Greene LM; Bergin O; Nathwani SM; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
    J Med Chem; 2010 Dec; 53(24):8569-84. PubMed ID: 21080725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR; Rhodes MR; Herald DL; Hamel E; Schmidt JM; Pettit RK
    J Med Chem; 2005 Jun; 48(12):4087-99. PubMed ID: 15943482
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K; Hentzen J; dit Chabert JF; Ducki S; Gani OA; Sylte I; Skrede M; Flørenes VA; Hansen TV
    Bioorg Med Chem; 2008 May; 16(9):4829-38. PubMed ID: 18396050
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity.
    Simoni D; Romagnoli R; Baruchello R; Rondanin R; Grisolia G; Eleopra M; Rizzi M; Tolomeo M; Giannini G; Alloatti D; Castorina M; Marcellini M; Pisano C
    J Med Chem; 2008 Oct; 51(19):6211-5. PubMed ID: 18783207
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel imidazole-based combretastatin A-4 analogues: evaluation of their in vitro antitumor activity and molecular modeling study of their binding to the colchicine site of tubulin.
    Bellina F; Cauteruccio S; Monti S; Rossi R
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5757-62. PubMed ID: 16950621
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationships of indole compounds derived from combretastatin A4: synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents.
    Ty N; Dupeyre G; Chabot GG; Seguin J; Quentin L; Chiaroni A; Tillequin F; Scherman D; Michel S; Cachet X
    Eur J Med Chem; 2010 Sep; 45(9):3726-39. PubMed ID: 20538383
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and structure-activity relationships of constrained heterocyclic analogues of combretastatin A4.
    Arthuis M; Pontikis R; Chabot GG; Seguin J; Quentin L; Bourg S; Morin-Allory L; Florent JC
    ChemMedChem; 2011 Sep; 6(9):1693-705. PubMed ID: 21732536
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects.
    Barrett I; Carr M; O'Boyle N; Greene LM; Knox AJ; Lloyd DG; Zisterer DM; Meegan MJ
    J Enzyme Inhib Med Chem; 2010 Apr; 25(2):180-94. PubMed ID: 20222762
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of cyclopropylamide analogues of combretastatin-A4 as novel microtubule-stabilizing agents.
    Chen H; Li Y; Sheng C; Lv Z; Dong G; Wang T; Liu J; Zhang M; Li L; Zhang T; Geng D; Niu C; Li K
    J Med Chem; 2013 Feb; 56(3):685-99. PubMed ID: 23356786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor.
    Ganina OG; Daras E; Bourgarel-Rey V; Peyrot V; Andresyuk AN; Finet JP; Fedorov AY; Beletskaya IP; Combes S
    Bioorg Med Chem; 2008 Oct; 16(19):8806-12. PubMed ID: 18805012
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of boronic acid containing cis-stilbenes as apoptotic tubulin polymerization inhibitors.
    Nakamura H; Kuroda H; Saito H; Suzuki R; Yamori T; Maruyama K; Haga T
    ChemMedChem; 2006 Jul; 1(7):729-40. PubMed ID: 16902927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors.
    Morellato L; Lefas-Le Gall M; Langlois M; Caignard DH; Renard P; Delagrange P; Mathé-Allainmat M
    Bioorg Med Chem Lett; 2013 Jan; 23(2):430-4. PubMed ID: 23265885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents.
    Reddy MA; Jain N; Yada D; Kishore C; Vangala JR; P Surendra R; Addlagatta A; Kalivendi SV; Sreedhar B
    J Med Chem; 2011 Oct; 54(19):6751-60. PubMed ID: 21851083
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.