These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. The delta-opioid receptor is sufficient, but not necessary, for spinal opioid-adrenergic analgesic synergy. Chabot-Doré AJ; Millecamps M; Stone LS J Pharmacol Exp Ther; 2013 Dec; 347(3):773-80. PubMed ID: 24039246 [TBL] [Abstract][Full Text] [Related]
5. ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors. Stone LS; Kitto KF; Eisenach JC; Fairbanks CA; Wilcox GL J Pharmacol Exp Ther; 2007 Dec; 323(3):899-906. PubMed ID: 17855473 [TBL] [Abstract][Full Text] [Related]
6. Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice. Tham SM; Angus JA; Tudor EM; Wright CE Br J Pharmacol; 2005 Mar; 144(6):875-84. PubMed ID: 15778704 [TBL] [Abstract][Full Text] [Related]
7. Morphine and clonidine combination therapy improves therapeutic window in mice: synergy in antinociceptive but not in sedative or cardiovascular effects. Stone LS; German JP; Kitto KF; Fairbanks CA; Wilcox GL PLoS One; 2014; 9(10):e109903. PubMed ID: 25299457 [TBL] [Abstract][Full Text] [Related]
8. Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice. Hunter JC; Fontana DJ; Hedley LR; Jasper JR; Lewis R; Link RE; Secchi R; Sutton J; Eglen RM Br J Pharmacol; 1997 Dec; 122(7):1339-44. PubMed ID: 9421280 [TBL] [Abstract][Full Text] [Related]
9. Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord. Overland AC; Kitto KF; Chabot-Doré AJ; Rothwell PE; Fairbanks CA; Stone LS; Wilcox GL J Neurosci; 2009 Oct; 29(42):13264-73. PubMed ID: 19846714 [TBL] [Abstract][Full Text] [Related]
10. The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy. Stone LS; MacMillan LB; Kitto KF; Limbird LE; Wilcox GL J Neurosci; 1997 Sep; 17(18):7157-65. PubMed ID: 9278550 [TBL] [Abstract][Full Text] [Related]
11. Contribution of α2A-adrenoceptor subtype to effect of dexmedetomidine and xylazine on spinal synaptic transmission of mice. Kobayashi T; Otsuguro K; Yamaguchi S; Ito S Eur J Pharmacol; 2015 Aug; 761():321-9. PubMed ID: 26086861 [TBL] [Abstract][Full Text] [Related]
12. Systemic daily morphine enhances the analgesic effect of intrathecal dexmedetomidine via up-regulation of alpha 2 adrenergic receptor subtypes A, B and C in dorsal root ganglion and dorsal horn. Tamagaki S; Suzuki T; Hagihira S; Hayashi Y; Mashimo T J Pharm Pharmacol; 2010 Dec; 62(12):1760-7. PubMed ID: 21054403 [TBL] [Abstract][Full Text] [Related]
13. Protein kinase Cε is required for spinal analgesic synergy between delta opioid and alpha-2A adrenergic receptor agonist pairs. Schuster DJ; Kitto KF; Overland AC; Messing RO; Stone LS; Fairbanks CA; Wilcox GL J Neurosci; 2013 Aug; 33(33):13538-46. PubMed ID: 23946412 [TBL] [Abstract][Full Text] [Related]
14. DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice. Guo XH; Fairbanks CA; Stone LS; Loh HH Pain; 2003 Jul; 104(1-2):209-17. PubMed ID: 12855331 [TBL] [Abstract][Full Text] [Related]
15. Spinal antinociceptive action of amiloride and its interaction with tizanidine in the rat formalin test. Ouyang H; Wang P; Huang W; Li Q; Nie B; Zeng W Pain Res Manag; 2015; 20(6):321-6. PubMed ID: 26357686 [TBL] [Abstract][Full Text] [Related]
16. The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats. Nishiyama T; Hanaoka K Anesth Analg; 2001 Oct; 93(4):1025-31. PubMed ID: 11574377 [TBL] [Abstract][Full Text] [Related]
17. Desensitization to the behavioral effects of alpha 2-adrenergic agonists in rats. Hayashi Y; Guo TZ; Maze M Anesthesiology; 1995 Apr; 82(4):954-62. PubMed ID: 7717568 [TBL] [Abstract][Full Text] [Related]