These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 19216841)

  • 1. Perifosine: update on a novel Akt inhibitor.
    Gills JJ; Dennis PA
    Curr Oncol Rep; 2009 Mar; 11(2):102-10. PubMed ID: 19216841
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation.
    Kondapaka SB; Singh SS; Dasmahapatra GP; Sausville EA; Roy KK
    Mol Cancer Ther; 2003 Nov; 2(11):1093-103. PubMed ID: 14617782
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic consequences of treatment with AKT inhibitor perifosine in breast cancer cells.
    Su JS; Woods SM; Ronen SM
    NMR Biomed; 2012 Feb; 25(2):379-88. PubMed ID: 22253088
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two phase 2 trials of the novel Akt inhibitor perifosine in patients with advanced renal cell carcinoma after progression on vascular endothelial growth factor-targeted therapy.
    Cho DC; Hutson TE; Samlowski W; Sportelli P; Somer B; Richards P; Sosman JA; Puzanov I; Michaelson MD; Flaherty KT; Figlin RA; Vogelzang NJ
    Cancer; 2012 Dec; 118(24):6055-62. PubMed ID: 22674198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Current view on the mechanism of action of perifosine in cancer.
    Fensterle J; Aicher B; Seipelt I; Teifel M; Engel J
    Anticancer Agents Med Chem; 2014 May; 14(4):629-35. PubMed ID: 24628236
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
    Momota H; Nerio E; Holland EC
    Cancer Res; 2005 Aug; 65(16):7429-35. PubMed ID: 16103096
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
    Li Z; Tan F; Liewehr DJ; Steinberg SM; Thiele CJ
    J Natl Cancer Inst; 2010 Jun; 102(11):758-70. PubMed ID: 20463309
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D; Hideshima T; Rodig S; Santo L; Pozzi S; Vallet S; Ikeda H; Perrone G; Gorgun G; Patel K; Desai N; Sportelli P; Kapoor S; Vali S; Mukherjee S; Munshi NC; Anderson KC; Raje N
    Mol Cancer Ther; 2010 Apr; 9(4):963-75. PubMed ID: 20371718
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
    Chiarini F; Del Sole M; Mongiorgi S; Gaboardi GC; Cappellini A; Mantovani I; Follo MY; McCubrey JA; Martelli AM
    Leukemia; 2008 Jun; 22(6):1106-16. PubMed ID: 18385752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
    Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
    Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perifosine as a potential novel anti-cancer agent inhibits EGFR/MET-AKT axis in malignant pleural mesothelioma.
    Pinton G; Manente AG; Angeli G; Mutti L; Moro L
    PLoS One; 2012; 7(5):e36856. PubMed ID: 22590625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Perifosine--a new option in treatment of acute myeloid leukemia?
    Krawczyk J; Keane N; Swords R; O'Dwyer M; Freeman CL; Giles FJ
    Expert Opin Investig Drugs; 2013 Oct; 22(10):1315-27. PubMed ID: 23931614
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest.
    Al Sawah E; Chen X; Marchion DC; Xiong Y; Ramirez IJ; Abbasi F; Bou Zgheib N; Chon HS; Wenham RM; Apte SM; Judson PL; Lancaster JM
    Gynecol Oncol; 2013 Oct; 131(1):207-12. PubMed ID: 23877012
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenstrom's macroglobulinemia.
    Ghobrial IM; Roccaro A; Hong F; Weller E; Rubin N; Leduc R; Rourke M; Chuma S; Sacco A; Jia X; Azab F; Azab AK; Rodig S; Warren D; Harris B; Varticovski L; Sportelli P; Leleu X; Anderson KC; Richardson PG
    Clin Cancer Res; 2010 Feb; 16(3):1033-41. PubMed ID: 20103671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Akt Inhibitor Perifosine Prevents Epileptogenesis in a Rat Model of Temporal Lobe Epilepsy.
    Zhu F; Kai J; Chen L; Wu M; Dong J; Wang Q; Zeng LH
    Neurosci Bull; 2018 Apr; 34(2):283-290. PubMed ID: 28786074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perifosine , an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity.
    Richardson PG; Eng C; Kolesar J; Hideshima T; Anderson KC
    Expert Opin Drug Metab Toxicol; 2012 May; 8(5):623-33. PubMed ID: 22512706
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA; Lin YD; Yue P; Wang X; Lonial S; Khuri FR; Sun SY
    Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
    Tazzari PL; Tabellini G; Ricci F; Papa V; Bortul R; Chiarini F; Evangelisti C; Martinelli G; Bontadini A; Cocco L; McCubrey JA; Martelli AM
    Cancer Res; 2008 Nov; 68(22):9394-403. PubMed ID: 19010914
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
    Leleu X; Jia X; Runnels J; Ngo HT; Moreau AS; Farag M; Spencer JA; Pitsillides CM; Hatjiharissi E; Roccaro A; O'Sullivan G; McMillin DW; Moreno D; Kiziltepe T; Carrasco R; Treon SP; Hideshima T; Anderson KC; Lin CP; Ghobrial IM
    Blood; 2007 Dec; 110(13):4417-26. PubMed ID: 17761832
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Perifosine-mediated Akt inhibition in neuroendocrine tumor cells: role of specific Akt isoforms.
    Zitzmann K; Vlotides G; Brand S; Lahm H; Spöttl G; Göke B; Auernhammer CJ
    Endocr Relat Cancer; 2012 Jun; 19(3):423-34. PubMed ID: 22499437
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.