BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 19218365)

  • 1. Homology modeling and site-directed mutagenesis reveal catalytic key amino acids of 3beta-hydroxysteroid-dehydrogenase/C4-decarboxylase from Arabidopsis.
    Rahier A; Bergdoll M; Génot G; Bouvier F; Camara B
    Plant Physiol; 2009 Apr; 149(4):1872-86. PubMed ID: 19218365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.
    Rahier A; Darnet S; Bouvier F; Camara B; Bard M
    J Biol Chem; 2006 Sep; 281(37):27264-77. PubMed ID: 16835224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dissecting the sterol C-4 demethylation process in higher plants. From structures and genes to catalytic mechanism.
    Rahier A
    Steroids; 2011 Mar; 76(4):340-52. PubMed ID: 21147141
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arabidopsis 3β-Hydroxysteroid Dehydrogenases/C4-Decarboxylases Are Essential for the Pollen and Embryonic Development.
    Pan J; Li W; Chen B; Liu L; Zhang J; Li J
    Int J Mol Sci; 2023 Oct; 24(21):. PubMed ID: 37958553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Serine 124 completes the Tyr, Lys and Ser triad responsible for the catalysis of human type 1 3beta-hydroxysteroid dehydrogenase.
    Thomas JL; Duax WL; Addlagatta A; Scaccia LA; Frizzell KA; Carloni SB
    J Mol Endocrinol; 2004 Aug; 33(1):253-61. PubMed ID: 15291757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of 3β-hydroxysteroid dehydrogenases/C-4 decarboxylases causes growth defects possibly due to abnormal auxin transport in Arabidopsis.
    Kim B; Kim G; Fujioka S; Takatsuto S; Choe S
    Mol Cells; 2012 Jul; 34(1):77-84. PubMed ID: 22673766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular modeling and site-directed mutagenesis reveal essential residues for catalysis in a prokaryote-type aspartate aminotransferase.
    de la Torre F; Moya-García AA; Suárez MF; Rodríguez-Caso C; Cañas RA; Sánchez-Jiménez F; Cánovas FM
    Plant Physiol; 2009 Apr; 149(4):1648-60. PubMed ID: 19176717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme.
    Huang YW; Pineau I; Chang HJ; Azzi A; Bellemare V; Laberge S; Lin SX
    Mol Endocrinol; 2001 Nov; 15(11):2010-20. PubMed ID: 11682630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rational proteomics V: structure-based mutagenesis has revealed key residues responsible for substrate recognition and catalysis by the dehydrogenase and isomerase activities in human 3beta-hydroxysteroid dehydrogenase/isomerase type 1.
    Pletnev VZ; Thomas JL; Rhaney FL; Holt LS; Scaccia LA; Umland TC; Duax WL
    J Steroid Biochem Mol Biol; 2006 Sep; 101(1):50-60. PubMed ID: 16889958
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics.
    McKeever BM; Hawkins BK; Geissler WM; Wu L; Sheridan RP; Mosley RT; Andersson S
    Biochim Biophys Acta; 2002 Nov; 1601(1):29-37. PubMed ID: 12429500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning, prokaryotic expression and function of the Bufo bufo gargarizans 3β-hydroxysteroid dehydrogenase (3βHSD) gene.
    Xu D; Wu M; Li X; Xia M; Liu D; Dai Y; Yu Q; Wu B; Wang D
    Int J Biol Macromol; 2018 Dec; 120(Pt A):673-682. PubMed ID: 30170058
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular framework of steroid/retinoid discrimination in 17beta-hydroxysteroid dehydrogenase type 1 and photoreceptor-associated retinol dehydrogenase.
    Haller F; Moman E; Hartmann RW; Adamski J; Mindnich R
    J Mol Biol; 2010 Jun; 399(2):255-67. PubMed ID: 20382160
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development.
    Engeli RT; Rhouma BB; Sager CP; Tsachaki M; Birk J; Fakhfakh F; Keskes L; Belguith N; Odermatt A
    J Steroid Biochem Mol Biol; 2016 Jan; 155(Pt A):147-54. PubMed ID: 26545797
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New insight into the molecular basis of 3beta-hydroxysteroid dehydrogenase deficiency: identification of eight mutations in the HSD3B2 gene eleven patients from seven new families and comparison of the functional properties of twenty-five mutant enzymes.
    Moisan AM; Ricketts ML; Tardy V; Desrochers M; Mébarki F; Chaussain JL; Cabrol S; Raux-Demay MC; Forest MG; Sippell WG; Peter M; Morel Y; Simard J
    J Clin Endocrinol Metab; 1999 Dec; 84(12):4410-25. PubMed ID: 10599696
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity.
    Thomas JL; Mason JI; Brandt S; Spencer BR; Norris W
    J Biol Chem; 2002 Nov; 277(45):42795-801. PubMed ID: 12205101
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structures important in mammalian 11 beta- and 17 beta-hydroxysteroid dehydrogenases.
    Tsigelny I; Baker ME
    J Steroid Biochem Mol Biol; 1995 Dec; 55(5-6):589-600. PubMed ID: 8547186
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2.
    Thomas JL; Boswell EL; Scaccia LA; Pletnev V; Umland TC
    J Biol Chem; 2005 Jun; 280(22):21321-8. PubMed ID: 15797861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis.
    Gachotte D; Barbuch R; Gaylor J; Nickel E; Bard M
    Proc Natl Acad Sci U S A; 1998 Nov; 95(23):13794-9. PubMed ID: 9811880
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants.
    Hoover GJ; Jørgensen R; Rochon A; Bajwa VS; Merrill AR; Shelp BJ
    Biochim Biophys Acta; 2013 Dec; 1834(12):2663-71. PubMed ID: 24076009
    [TBL] [Abstract][Full Text] [Related]  

  • 20. At5g50600 encodes a member of the short-chain dehydrogenase reductase superfamily with 11beta- and 17beta-hydroxysteroid dehydrogenase activities associated with Arabidopsis thaliana seed oil bodies.
    d'Andréa S; Canonge M; Beopoulos A; Jolivet P; Hartmann MA; Miquel M; Lepiniec L; Chardot T
    Biochimie; 2007 Feb; 89(2):222-9. PubMed ID: 17074428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.