375 related articles for article (PubMed ID: 19223185)
1. Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening.
Turk S; Kovac A; Boniface A; Bostock JM; Chopra I; Blanot D; Gobec S
Bioorg Med Chem; 2009 Mar; 17(5):1884-9. PubMed ID: 19223185
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.
Hrast M; Turk S; Sosič I; Knez D; Randall CP; Barreteau H; Contreras-Martel C; Dessen A; O'Neill AJ; Mengin-Lecreulx D; Blanot D; Gobec S
Eur J Med Chem; 2013 Aug; 66():32-45. PubMed ID: 23786712
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach.
Perdih A; Kovac A; Wolber G; Blanot D; Gobec S; Solmajer T
Bioorg Med Chem Lett; 2009 May; 19(10):2668-73. PubMed ID: 19369074
[TBL] [Abstract][Full Text] [Related]
4. Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF.
Sova M; Kovac A; Turk S; Hrast M; Blanot D; Gobec S
Bioorg Chem; 2009 Dec; 37(6):217-22. PubMed ID: 19804894
[TBL] [Abstract][Full Text] [Related]
5. Benzene-1,3-dicarboxylic acid 2,5-dimethylpyrrole derivatives as multiple inhibitors of bacterial Mur ligases (MurC-MurF).
Perdih A; Hrast M; Barreteau H; Gobec S; Wolber G; Solmajer T
Bioorg Med Chem; 2014 Aug; 22(15):4124-34. PubMed ID: 24953950
[TBL] [Abstract][Full Text] [Related]
6. Discovery of new inhibitors of D-alanine:D-alanine ligase by structure-based virtual screening.
Kovac A; Konc J; Vehar B; Bostock JM; Chopra I; Janezic D; Gobec S
J Med Chem; 2008 Dec; 51(23):7442-8. PubMed ID: 19053785
[TBL] [Abstract][Full Text] [Related]
7. Phosphinate inhibitors of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: L-lysine ligase (MurE).
Strancar K; Boniface A; Blanot D; Gobec S
Arch Pharm (Weinheim); 2007 Mar; 340(3):127-34. PubMed ID: 17335103
[TBL] [Abstract][Full Text] [Related]
8. Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.
Humljan J; Kotnik M; Contreras-Martel C; Blanot D; Urleb U; Dessen A; Solmajer T; Gobec S
J Med Chem; 2008 Dec; 51(23):7486-94. PubMed ID: 19007109
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.
Tomasić T; Zidar N; Rupnik V; Kovac A; Blanot D; Gobec S; Kikelj D; Masic LP
Bioorg Med Chem Lett; 2009 Jan; 19(1):153-7. PubMed ID: 19014883
[TBL] [Abstract][Full Text] [Related]
10. 5-Benzylidenethiazolidin-4-ones as multitarget inhibitors of bacterial Mur ligases.
Tomasić T; Zidar N; Kovac A; Turk S; Simcic M; Blanot D; Müller-Premru M; Filipic M; Grdadolnik SG; Zega A; Anderluh M; Gobec S; Kikelj D; Peterlin Masic L
ChemMedChem; 2010 Feb; 5(2):286-95. PubMed ID: 20024979
[TBL] [Abstract][Full Text] [Related]
11. MurD enzymes: some recent developments.
Šink R; Barreteau H; Patin D; Mengin-Lecreulx D; Gobec S; Blanot D
Biomol Concepts; 2013 Dec; 4(6):539-56. PubMed ID: 25436755
[TBL] [Abstract][Full Text] [Related]
12. Inhibitor design strategy based on an enzyme structural flexibility: a case of bacterial MurD ligase.
Perdih A; Hrast M; Barreteau H; Gobec S; Wolber G; Solmajer T
J Chem Inf Model; 2014 May; 54(5):1451-66. PubMed ID: 24724969
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases.
Sink R; Kovac A; Tomasić T; Rupnik V; Boniface A; Bostock J; Chopra I; Blanot D; Masic LP; Gobec S; Zega A
ChemMedChem; 2008 Sep; 3(9):1362-70. PubMed ID: 18651694
[TBL] [Abstract][Full Text] [Related]
14. Peptide inhibitors of MurD and MurE, essential enzymes of bacterial cell wall biosynthesis.
Bratkovic T; Lunder M; Urleb U; Strukelj B
J Basic Microbiol; 2008 Jun; 48(3):202-6. PubMed ID: 18506905
[TBL] [Abstract][Full Text] [Related]
15. Structure-based optimization of MurF inhibitors.
Stamper GF; Longenecker KL; Fry EH; Jakob CG; Florjancic AS; Gu YG; Anderson DD; Cooper CS; Zhang T; Clark RF; Cia Y; Black-Schaefer CL; Owen McCall J; Lerner CG; Hajduk PJ; Beutel BA; Stoll VS
Chem Biol Drug Des; 2006 Jan; 67(1):58-65. PubMed ID: 16492149
[TBL] [Abstract][Full Text] [Related]
16. Furan-based benzene mono- and dicarboxylic acid derivatives as multiple inhibitors of the bacterial Mur ligases (MurC-MurF): experimental and computational characterization.
Perdih A; Hrast M; Pureber K; Barreteau H; Grdadolnik SG; Kocjan D; Gobec S; Solmajer T; Wolber G
J Comput Aided Mol Des; 2015 Jun; 29(6):541-60. PubMed ID: 25851408
[TBL] [Abstract][Full Text] [Related]
17. A novel assay of bacterial peptidoglycan synthesis for natural product screening.
Murakami R; Muramatsu Y; Minami E; Masuda K; Sakaida Y; Endo S; Suzuki T; Ishida O; Takatsu T; Miyakoshi S; Inukai M; Isono F
J Antibiot (Tokyo); 2009 Mar; 62(3):153-8. PubMed ID: 19229285
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.
Strancar K; Blanot D; Gobec S
Bioorg Med Chem Lett; 2006 Jan; 16(2):343-8. PubMed ID: 16271472
[TBL] [Abstract][Full Text] [Related]
19. Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF.
Baum EZ; Crespo-Carbone SM; Abbanat D; Foleno B; Maden A; Goldschmidt R; Bush K
Antimicrob Agents Chemother; 2006 Jan; 50(1):230-6. PubMed ID: 16377691
[TBL] [Abstract][Full Text] [Related]
20. New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.
Zidar N; Tomašić T; Šink R; Kovač A; Patin D; Blanot D; Contreras-Martel C; Dessen A; Premru MM; Zega A; Gobec S; Mašič LP; Kikelj D
Eur J Med Chem; 2011 Nov; 46(11):5512-23. PubMed ID: 21963114
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]