BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 19235590)

  • 1. Improved response by co-targeting EGFR/EGFRvIII and Src family kinases in human cancer cells.
    Andersen P; Villingshøj M; Poulsen HS; Stockhausen MT
    Cancer Invest; 2009 Feb; 27(2):178-83. PubMed ID: 19235590
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.
    Hiscox S; Morgan L; Green TP; Barrow D; Gee J; Nicholson RI
    Breast Cancer Res Treat; 2006 Jun; 97(3):263-74. PubMed ID: 16333527
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SRC promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy.
    Leung EL; Tam IY; Tin VP; Chua DT; Sihoe AD; Cheng LC; Ho JC; Chung LP; Wong MP
    Mol Cancer Res; 2009 Jun; 7(6):923-32. PubMed ID: 19491201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII.
    Pedersen MW; Pedersen N; Ottesen LH; Poulsen HS
    Br J Cancer; 2005 Oct; 93(8):915-23. PubMed ID: 16189524
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer.
    Dominguez-Escrig JL; Kelly JD; Neal DE; King SM; Davies BR
    Clin Cancer Res; 2004 Jul; 10(14):4874-84. PubMed ID: 15269164
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells.
    Qin B; Ariyama H; Baba E; Tanaka R; Kusaba H; Harada M; Nakano S
    Cancer Chemother Pharmacol; 2006 Nov; 58(5):577-84. PubMed ID: 16532343
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting.
    Matar P; Rojo F; Cassia R; Moreno-Bueno G; Di Cosimo S; Tabernero J; Guzmán M; Rodriguez S; Arribas J; Palacios J; Baselga J
    Clin Cancer Res; 2004 Oct; 10(19):6487-501. PubMed ID: 15475436
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel oxazolo[4,5-g]quinazolin-2(1H)-ones: dual inhibitors of EGFR and Src protein tyrosine kinases.
    Lin J; Shen W; Xue J; Sun J; Zhang X; Zhang C
    Eur J Med Chem; 2012 Sep; 55():39-48. PubMed ID: 22818848
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biological effects of AL622, a molecule rationally designed to release an EGFR and a c-Src kinase inhibitor.
    Larroque-Lombard AL; Ning N; Rao S; Lauwagie S; Halaoui R; Coudray L; Huang Y; Jean-Claude BJ
    Chem Biol Drug Des; 2012 Dec; 80(6):981-91. PubMed ID: 22943437
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epidermal growth factor receptor activity determines response of colorectal cancer cells to gefitinib alone and in combination with chemotherapy.
    Van Schaeybroeck S; Karaiskou-McCaul A; Kelly D; Longley D; Galligan L; Van Cutsem E; Johnston P
    Clin Cancer Res; 2005 Oct; 11(20):7480-9. PubMed ID: 16243822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epidermal growth factor-independent transformation of Ba/F3 cells with cancer-derived epidermal growth factor receptor mutants induces gefitinib-sensitive cell cycle progression.
    Jiang J; Greulich H; Jänne PA; Sellers WR; Meyerson M; Griffin JD
    Cancer Res; 2005 Oct; 65(19):8968-74. PubMed ID: 16204070
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enediyne lidamycin enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib, in epidermoid carcinoma A431 cells and lung carcinoma H460 cells.
    Liu H; Li L; Li XQ; Liu XJ; Zhen YS
    Anticancer Drugs; 2009 Jan; 20(1):41-9. PubMed ID: 19342999
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival.
    Song L; Morris M; Bagui T; Lee FY; Jove R; Haura EB
    Cancer Res; 2006 Jun; 66(11):5542-8. PubMed ID: 16740687
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration.
    Bai L; Yang JC; Ok JH; Mack PC; Kung HJ; Evans CP
    Int J Cancer; 2012 Jun; 130(11):2693-702. PubMed ID: 21792888
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2.
    Chang CM; Chang PY; Tu MG; Lu CC; Kuo SC; Amagaya S; Lee CY; Jao HY; Chen MY; Yang JS
    Oncol Rep; 2012 Nov; 28(5):1799-807. PubMed ID: 22923287
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Responses of human colorectal tumor cells to treatment with the anti-epidermal growth factor receptor monoclonal antibody ICR62 used alone and in combination with the EGFR tyrosine kinase inhibitor gefitinib.
    Cunningham MP; Thomas H; Fan Z; Modjtahedi H
    Cancer Res; 2006 Aug; 66(15):7708-15. PubMed ID: 16885373
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.
    Fu YN; Yeh CL; Cheng HH; Yang CH; Tsai SF; Huang SF; Chen YR
    Oncogene; 2008 Feb; 27(7):957-65. PubMed ID: 17653080
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines.
    Dai Q; Ling YH; Lia M; Zou YY; Kroog G; Iwata KK; Perez-Soler R
    Clin Cancer Res; 2005 Feb; 11(4):1572-8. PubMed ID: 15746062
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.
    Donev IS; Wang W; Yamada T; Li Q; Takeuchi S; Matsumoto K; Yamori T; Nishioka Y; Sone S; Yano S
    Clin Cancer Res; 2011 Apr; 17(8):2260-9. PubMed ID: 21220474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
    Hirata A; Hosoi F; Miyagawa M; Ueda S; Naito S; Fujii T; Kuwano M; Ono M
    Cancer Res; 2005 May; 65(10):4253-60. PubMed ID: 15899817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.