502 related articles for article (PubMed ID: 19237285)
1. Benzimidazolone-based serotonin 5-HT1A or 5-HT7R ligands: synthesis and biological evaluation.
Badarau E; Suzenet F; Bojarski AJ; Fînaru AL; Guillaumet G
Bioorg Med Chem Lett; 2009 Mar; 19(6):1600-3. PubMed ID: 19237285
[TBL] [Abstract][Full Text] [Related]
2. New insights into homopiperazine-based 5-HT1A/5-HT7R ligands: synthesis and biological evaluation.
Badarau E; Putey A; Suzenet F; Joseph B; Bojarski A; Finaru A; Guillaumet G
J Enzyme Inhib Med Chem; 2010 Jun; 25(3):301-5. PubMed ID: 19874209
[TBL] [Abstract][Full Text] [Related]
3. The impact of spacer structure on 5-HT7 and 5-HT1A receptor affinity in the group of long-chain arylpiperazine ligands.
Bojarski AJ; Duszyńska B; Kołaczkowski M; Kowalski P; Kowalska T
Bioorg Med Chem Lett; 2004 Dec; 14(23):5863-6. PubMed ID: 15501057
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands.
Siracusa MA; Salerno L; Modica MN; Pittalà V; Romeo G; Amato ME; Nowak M; Bojarski AJ; Mereghetti I; Cagnotto A; Mennini T
J Med Chem; 2008 Aug; 51(15):4529-38. PubMed ID: 18598015
[TBL] [Abstract][Full Text] [Related]
5. Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: synthesis and binding affinities for 5-HT(7) and 5-HT(1A) receptors.
Leopoldo M; Lacivita E; Colabufo NA; Niso M; Berardi F; Perrone R
Bioorg Med Chem; 2007 Aug; 15(15):5316-21. PubMed ID: 17517509
[TBL] [Abstract][Full Text] [Related]
6. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
Fiorino F; Perissutti E; Severino B; Santagada V; Cirillo D; Terracciano S; Massarelli P; Bruni G; Collavoli E; Renner C; Caliendo G
J Med Chem; 2005 Aug; 48(17):5495-503. PubMed ID: 16107148
[TBL] [Abstract][Full Text] [Related]
7. A new class of arylpiperazine derivatives: the library synthesis on SynPhase lanterns and biological evaluation on serotonin 5-HT(1A) and 5-HT(2A) receptors.
Zajdel P; Subra G; Bojarski AJ; Duszyńska B; Pawłowski M; Martinez J
J Comb Chem; 2004; 6(5):761-7. PubMed ID: 15360211
[TBL] [Abstract][Full Text] [Related]
8. Application of desirability-based multi(bi)-objective optimization in the design of selective arylpiperazine derivates for the 5-HT1A serotonin receptor.
Machado A; Tejera E; Cruz-Monteagudo M; Rebelo I
Eur J Med Chem; 2009 Dec; 44(12):5045-54. PubMed ID: 19846239
[TBL] [Abstract][Full Text] [Related]
9. A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.
Liu KG; Lo JR; Comery TA; Zhang GM; Zhang JY; Kowal DM; Smith DL; Di L; Kerns EH; Schechter LE; Robichaud AJ
Bioorg Med Chem Lett; 2008 Jul; 18(14):3929-31. PubMed ID: 18583130
[TBL] [Abstract][Full Text] [Related]
10. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
[TBL] [Abstract][Full Text] [Related]
11. Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
López-Rodríguez ML; Benhamú B; Morcillo MJ; Tejada I; Avila D; Marco I; Schiapparelli L; Frechilla D; Del Río J
Bioorg Med Chem; 2004 Oct; 12(19):5181-91. PubMed ID: 15351401
[TBL] [Abstract][Full Text] [Related]
12. 4-Aminoethylpiperazinyl aryl ketones with 5-HT₁A/5-HT₇ selectivity.
Kim MK; Lee HS; Kim S; Cho SY; Roth BL; Chong Y; Choo H
Bioorg Med Chem; 2012 Jan; 20(2):1139-48. PubMed ID: 22196512
[TBL] [Abstract][Full Text] [Related]
13. 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.
Sorbi C; Franchini S; Tait A; Prandi A; Gallesi R; Angeli P; Marucci G; Pirona L; Poggesi E; Brasili L
ChemMedChem; 2009 Mar; 4(3):393-9. PubMed ID: 19152363
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity.
Medina RA; Sallander J; Benhamú B; Porras E; Campillo M; Pardo L; López-Rodríguez ML
J Med Chem; 2009 Apr; 52(8):2384-92. PubMed ID: 19326916
[TBL] [Abstract][Full Text] [Related]
15. Molecular modeling studies focused on 5-HT7 versus 5-HT1A selectivity. Discovery of novel phenylpyrrole derivatives with high affinity for 5-HT7 receptors.
Lepailleur A; Bureau R; Paillet-Loilier M; Fabis F; Saettel N; Lemaître S; Dauphin F; Lesnard A; Lancelot JC; Rault S
J Chem Inf Model; 2005; 45(4):1075-81. PubMed ID: 16045303
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT(7) and 5-HT(1A) receptor ligands.
Salerno L; Pittalà V; Modica MN; Siracusa MA; Intagliata S; Cagnotto A; Salmona M; Kurczab R; Bojarski AJ; Romeo G
Eur J Med Chem; 2014 Oct; 85():716-26. PubMed ID: 25128671
[TBL] [Abstract][Full Text] [Related]
17. Homology modeling of the serotonin 5-HT1A receptor using automated docking of bioactive compounds with defined geometry.
Nowak M; Kołaczkowski M; Pawłowski M; Bojarski AJ
J Med Chem; 2006 Jan; 49(1):205-14. PubMed ID: 16392805
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structural investigation of some pyrimido[5,4-c]quinolin-4(3H)-one derivatives with a long-chain arylpiperazine moiety as potent 5-HT(1A/2A) and 5-HT(7) receptor ligands.
Lewgowd W; Bojarski AJ; Szczesio M; Olczak A; Glowka ML; Mordalski S; Stanczak A
Eur J Med Chem; 2011 Aug; 46(8):3348-61. PubMed ID: 21601317
[TBL] [Abstract][Full Text] [Related]
19. Interaction of arylpiperazine ligands with the hydrophobic part of the 5-HT1A receptor binding site.
Zlatović MV; Sukalović VV; Schneider C; Roglić GM
Bioorg Med Chem; 2006 May; 14(9):2994-3001. PubMed ID: 16403641
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor.
Al Hussainy R; Verbeek J; van der Born D; Braker AH; Leysen JE; Knol RJ; Booij J; Herscheid JK
J Med Chem; 2011 May; 54(10):3480-91. PubMed ID: 21520940
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
