These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 19237515)

  • 1. Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.
    Niessen J; Jedlitschky G; Grube M; Bien S; Schwertz H; Ohtsuki S; Kawakami H; Kamiie J; Oswald S; Starke K; Strobel U; Siegmund W; Rosskopf D; Greinacher A; Terasaki T; Kroemer HK
    Drug Metab Dispos; 2009 May; 37(5):1129-37. PubMed ID: 19237515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
    Grube M; Köck K; Oswald S; Draber K; Meissner K; Eckel L; Böhm M; Felix SB; Vogelgesang S; Jedlitschky G; Siegmund W; Warzok R; Kroemer HK
    Clin Pharmacol Ther; 2006 Dec; 80(6):607-20. PubMed ID: 17178262
    [TBL] [Abstract][Full Text] [Related]  

  • 3. pH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1.
    Varma MV; Rotter CJ; Chupka J; Whalen KM; Duignan DB; Feng B; Litchfield J; Goosen TC; El-Kattan AF
    Mol Pharm; 2011 Aug; 8(4):1303-13. PubMed ID: 21710988
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclosporine A, but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin.
    Amundsen R; Christensen H; Zabihyan B; Asberg A
    Drug Metab Dispos; 2010 Sep; 38(9):1499-504. PubMed ID: 20519340
    [TBL] [Abstract][Full Text] [Related]  

  • 5. pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions.
    Kis O; Zastre JA; Ramaswamy M; Bendayan R
    J Pharmacol Exp Ther; 2010 Sep; 334(3):1009-22. PubMed ID: 20507927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions.
    Vildhede A; Karlgren M; Svedberg EK; Wisniewski JR; Lai Y; Norén A; Artursson P
    Drug Metab Dispos; 2014 Jul; 42(7):1210-8. PubMed ID: 24799396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human skeletal muscle drug transporters determine local exposure and toxicity of statins.
    Knauer MJ; Urquhart BL; Meyer zu Schwabedissen HE; Schwarz UI; Lemke CJ; Leake BF; Kim RB; Tirona RG
    Circ Res; 2010 Feb; 106(2):297-306. PubMed ID: 19940267
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.
    Lau YY; Okochi H; Huang Y; Benet LZ
    Drug Metab Dispos; 2006 Jul; 34(7):1175-81. PubMed ID: 16624870
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modification of OATP2B1-mediated transport by steroid hormones.
    Grube M; Köck K; Karner S; Reuther S; Ritter CA; Jedlitschky G; Kroemer HK
    Mol Pharmacol; 2006 Nov; 70(5):1735-41. PubMed ID: 16908597
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple transporters affect the disposition of atorvastatin and its two active hydroxy metabolites: application of in vitro and ex situ systems.
    Lau YY; Okochi H; Huang Y; Benet LZ
    J Pharmacol Exp Ther; 2006 Feb; 316(2):762-71. PubMed ID: 16258024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
    Ho RH; Tirona RG; Leake BF; Glaeser H; Lee W; Lemke CJ; Wang Y; Kim RB
    Gastroenterology; 2006 May; 130(6):1793-806. PubMed ID: 16697742
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.
    Choi MK; Shin HJ; Choi YL; Deng JW; Shin JG; Song IS
    Xenobiotica; 2011 Jan; 41(1):24-34. PubMed ID: 20946088
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The influence of oral antidiabetic drugs on cellular drug uptake mediated by hepatic OATP family members.
    Klatt S; Fromm MF; König J
    Basic Clin Pharmacol Toxicol; 2013 Apr; 112(4):244-50. PubMed ID: 23121773
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of five HMG-CoA reductase inhibitors-- atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies.
    Pasha MK; Muzeeb S; Basha SJ; Shashikumar D; Mullangi R; Srinivas NR
    Biomed Chromatogr; 2006 Mar; 20(3):282-93. PubMed ID: 16143964
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Statins have beneficial effects on platelet free radical activity and intracellular distribution of GTPases in hyperlipidaemia.
    Hamilton PK; Hughes SM; Plumb RD; Devine A; Leahey W; Lyons KS; Johnston D; McVeigh GE
    Clin Sci (Lond); 2010 Mar; 118(5):359-66. PubMed ID: 19740072
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake.
    Wen F; Shi M; Bian J; Zhang H; Gui C
    Pharm Biol; 2016; 54(2):293-302. PubMed ID: 25858254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Karlgren M; Vildhede A; Norinder U; Wisniewski JR; Kimoto E; Lai Y; Haglund U; Artursson P
    J Med Chem; 2012 May; 55(10):4740-63. PubMed ID: 22541068
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tissue-specific effects of atorvastatin on 3-hydroxy-3-methylglutarylcoenzyme A reductase expression and activity in spontaneously hypertensive rats.
    Chen GP; Yao L; Lu X; Li L; Hu SJ
    Acta Pharmacol Sin; 2008 Oct; 29(10):1181-6. PubMed ID: 18817622
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1.
    Mandery K; Bujok K; Schmidt I; Keiser M; Siegmund W; Balk B; König J; Fromm MF; Glaeser H
    Biochem Pharmacol; 2010 Dec; 80(11):1746-53. PubMed ID: 20797388
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells.
    Sai Y; Kaneko Y; Ito S; Mitsuoka K; Kato Y; Tamai I; Artursson P; Tsuji A
    Drug Metab Dispos; 2006 Aug; 34(8):1423-31. PubMed ID: 16714376
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.