BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 19238656)

  • 1. Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.
    Kharasch ED; Bedynek PS; Walker A; Whittington D; Hoffer C
    Clin Pharmacol Ther; 2008 Oct; 84(4):506-12. PubMed ID: 19238656
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: I. Evidence against CYP3A mediation of methadone clearance.
    Kharasch ED; Bedynek PS; Park S; Whittington D; Walker A; Hoffer C
    Clin Pharmacol Ther; 2008 Oct; 84(4):497-505. PubMed ID: 19238655
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir.
    Kharasch ED; Hoffer C; Whittington D; Walker A; Bedynek PS
    Anesthesiology; 2009 Mar; 110(3):660-72. PubMed ID: 19225389
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A).
    Kharasch ED; Bedynek PS; Hoffer C; Walker A; Whittington D
    Anesthesiology; 2012 Feb; 116(2):432-47. PubMed ID: 22273859
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.
    Ieiri I; Tsunemitsu S; Maeda K; Ando Y; Izumi N; Kimura M; Yamane N; Okuzono T; Morishita M; Kotani N; Kanda E; Deguchi M; Matsuguma K; Matsuki S; Hirota T; Irie S; Kusuhara H; Sugiyama Y
    J Clin Pharmacol; 2013 Jun; 53(6):654-61. PubMed ID: 23381882
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome P4503A does not mediate the interaction between methadone and ritonavir-lopinavir.
    Kharasch ED; Stubbert K
    Drug Metab Dispos; 2013 Dec; 41(12):2166-74. PubMed ID: 24067429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis.
    Kharasch ED; Walker A; Hoffer C; Sheffels P
    Clin Pharmacol Ther; 2004 Nov; 76(5):452-66. PubMed ID: 15536460
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects.
    Robertson SM; Davey RT; Voell J; Formentini E; Alfaro RM; Penzak SR
    Curr Med Res Opin; 2008 Feb; 24(2):591-9. PubMed ID: 18205997
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.
    van Waterschoot RA; ter Heine R; Wagenaar E; van der Kruijssen CM; Rooswinkel RW; Huitema AD; Beijnen JH; Schinkel AH
    Br J Pharmacol; 2010 Jul; 160(5):1224-33. PubMed ID: 20590614
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
    Kharasch ED; Walker A; Whittington D; Hoffer C; Bedynek PS
    Drug Alcohol Depend; 2009 May; 101(3):158-68. PubMed ID: 19232844
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disposition and miotic effects of oral alfentanil: a potential noninvasive probe for first-pass cytochrome P4503A activity.
    Kharasch ED; Hoffer C; Walker A; Sheffels P
    Clin Pharmacol Ther; 2003 Mar; 73(3):199-208. PubMed ID: 12621385
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Time-dependent interaction between lopinavir/ritonavir and fexofenadine.
    van Heeswijk RP; Bourbeau M; Campbell P; Seguin I; Chauhan BM; Foster BC; Cameron DW
    J Clin Pharmacol; 2006 Jul; 46(7):758-67. PubMed ID: 16809801
    [TBL] [Abstract][Full Text] [Related]  

  • 13. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
    Hendrikx JJ; Lagas JS; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
    Int J Cancer; 2013 May; 132(10):2439-47. PubMed ID: 23090875
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.
    Kharasch ED; Walker A; Hoffer C; Sheffels P
    J Clin Pharmacol; 2005 Jan; 45(1):79-88. PubMed ID: 15601808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.
    Kharasch ED; Hoffer C; Whittington D; Sheffels P
    Clin Pharmacol Ther; 2004 Sep; 76(3):250-69. PubMed ID: 15371986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity.
    Kharasch ED; Walker A; Hoffer C; Sheffels P
    J Clin Pharmacol; 2005 Oct; 45(10):1187-97. PubMed ID: 16172184
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone.
    Kharasch ED; Hoffer C; Whittington D
    Br J Clin Pharmacol; 2004 May; 57(5):600-10. PubMed ID: 15089813
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.
    Dumond JB; Vourvahis M; Rezk NL; Patterson KB; Tien HC; White N; Jennings SH; Choi SO; Li J; Wagner MJ; La-Beck NM; Drulak M; Sabo JP; Castles MA; Macgregor TR; Kashuba AD
    Clin Pharmacol Ther; 2010 Jun; 87(6):735-42. PubMed ID: 20147896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimal and noninvasive probes for hepatic and first-pass CYP3A induction.
    Kharasch ED; Francis A; London A; Frey K; Kim T; Blood J
    Clin Pharmacol Ther; 2011 Jul; 90(1):100-8. PubMed ID: 21562488
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of the pharmacokinetic boosting effects of ritonavir on oral bioavailability of drugs in mice.
    Tomaru A; Takeda-Morishita M; Banba H; Takayama K
    Drug Metab Pharmacokinet; 2013; 28(2):144-52. PubMed ID: 22971642
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.