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6. An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Ring AM; Leng Q; Rinehart J; Wilson FH; Kahle KT; Hebert SC; Lifton RP Proc Natl Acad Sci U S A; 2007 Mar; 104(10):4025-9. PubMed ID: 17360471 [TBL] [Abstract][Full Text] [Related]
7. WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3. Susa K; Sohara E; Takahashi D; Okado T; Rai T; Uchida S Biochem Biophys Res Commun; 2017 Sep; 491(3):727-732. PubMed ID: 28743496 [TBL] [Abstract][Full Text] [Related]
8. WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4. Chávez-Canales M; Zhang C; Soukaseum C; Moreno E; Pacheco-Alvarez D; Vidal-Petiot E; Castañeda-Bueno M; Vázquez N; Rojas-Vega L; Meermeier NP; Rogers S; Jeunemaitre X; Yang CL; Ellison DH; Gamba G; Hadchouel J Hypertension; 2014 Nov; 64(5):1047-53. PubMed ID: 25113964 [TBL] [Abstract][Full Text] [Related]
9. Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway. van der Lubbe N; Lim CH; Meima ME; van Veghel R; Rosenbaek LL; Mutig K; Danser AH; Fenton RA; Zietse R; Hoorn EJ Pflugers Arch; 2012 Jun; 463(6):853-63. PubMed ID: 22549242 [TBL] [Abstract][Full Text] [Related]
10. Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney. Sohara E; Rai T; Yang SS; Ohta A; Naito S; Chiga M; Nomura N; Lin SH; Vandewalle A; Ohta E; Sasaki S; Uchida S PLoS One; 2011; 6(8):e24277. PubMed ID: 21909387 [TBL] [Abstract][Full Text] [Related]
12. The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway. Bazúa-Valenti S; Rojas-Vega L; Castañeda-Bueno M; Barrera-Chimal J; Bautista R; Cervantes-Pérez LG; Vázquez N; Plata C; Murillo-de-Ozores AR; González-Mariscal L; Ellison DH; Riccardi D; Bobadilla NA; Gamba G J Am Soc Nephrol; 2018 Jul; 29(7):1838-1848. PubMed ID: 29848507 [No Abstract] [Full Text] [Related]
13. WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter. San-Cristobal P; Ponce-Coria J; Vázquez N; Bobadilla NA; Gamba G Am J Physiol Renal Physiol; 2008 Oct; 295(4):F1199-206. PubMed ID: 18701621 [TBL] [Abstract][Full Text] [Related]
14. Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling. Ishizawa K; Wang Q; Li J; Yamazaki O; Tamura Y; Fujigaki Y; Uchida S; Lifton RP; Shibata S Proc Natl Acad Sci U S A; 2019 Feb; 116(8):3155-3160. PubMed ID: 30718414 [TBL] [Abstract][Full Text] [Related]
15. WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. Kahle KT; Wilson FH; Leng Q; Lalioti MD; O'Connell AD; Dong K; Rapson AK; MacGregor GG; Giebisch G; Hebert SC; Lifton RP Nat Genet; 2003 Dec; 35(4):372-6. PubMed ID: 14608358 [TBL] [Abstract][Full Text] [Related]
16. WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo. Ring AM; Cheng SX; Leng Q; Kahle KT; Rinehart J; Lalioti MD; Volkman HM; Wilson FH; Hebert SC; Lifton RP Proc Natl Acad Sci U S A; 2007 Mar; 104(10):4020-4. PubMed ID: 17360470 [TBL] [Abstract][Full Text] [Related]
17. Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron. van der Lubbe N; Zietse R; Hoorn EJ Curr Opin Nephrol Hypertens; 2013 Jan; 22(1):120-6. PubMed ID: 23165113 [TBL] [Abstract][Full Text] [Related]
18. WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). Leng Q; Kahle KT; Rinehart J; MacGregor GG; Wilson FH; Canessa CM; Lifton RP; Hebert SC J Physiol; 2006 Mar; 571(Pt 2):275-86. PubMed ID: 16357011 [TBL] [Abstract][Full Text] [Related]
19. Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II. Cervantes-Perez LG; Castaneda-Bueno M; Jimenez JV; Vazquez N; Rojas-Vega L; Alessi DR; Bobadilla NA; Gamba G J Hypertens; 2018 Feb; 36(2):361-367. PubMed ID: 28877076 [TBL] [Abstract][Full Text] [Related]
20. Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model. Yang SS; Morimoto T; Rai T; Chiga M; Sohara E; Ohno M; Uchida K; Lin SH; Moriguchi T; Shibuya H; Kondo Y; Sasaki S; Uchida S Cell Metab; 2007 May; 5(5):331-44. PubMed ID: 17488636 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]