BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 19243127)

  • 1. The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole.
    Turesky RJ; Bendaly J; Yasa I; Doll MA; Hein DW
    Chem Res Toxicol; 2009 Apr; 22(4):726-33. PubMed ID: 19243127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline-induced DNA adduct formation and mutagenesis in DNA repair-deficient Chinese hamster ovary cells expressing human cytochrome P4501A1 and rapid or slow acetylator N-acetyltransferase 2.
    Bendaly J; Zhao S; Neale JR; Metry KJ; Doll MA; States JC; Pierce WM; Hein DW
    Cancer Epidemiol Biomarkers Prev; 2007 Jul; 16(7):1503-9. PubMed ID: 17627018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.
    Metry KJ; Zhao S; Neale JR; Doll MA; States JC; McGregor WG; Pierce WM; Hein DW
    Mol Carcinog; 2007 Jul; 46(7):553-63. PubMed ID: 17295238
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations.
    Bendaly J; Doll MA; Millner LM; Metry KJ; Smith NB; Pierce WM; Hein DW
    Mutat Res; 2009 Dec; 671(1-2):13-9. PubMed ID: 19682468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes.
    Bellamri M; Le Hegarat L; Turesky RJ; Langouët S
    Chem Res Toxicol; 2017 Feb; 30(2):657-668. PubMed ID: 27976871
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of Human N-Acetyltransferase 2 Genetic Polymorphism on Aromatic Amine Carcinogen-Induced DNA Damage and Mutagenicity in a Chinese Hamster Ovary Cell Mutation Assay.
    Baldauf KJ; Salazar-González RA; Doll MA; Pierce WM; States JC; Hein DW
    Environ Mol Mutagen; 2020 Feb; 61(2):235-245. PubMed ID: 31490564
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Amino-9H-pyrido[2,3-b]indole (AαC) Adducts and Thiol Oxidation of Serum Albumin as Potential Biomarkers of Tobacco Smoke.
    Pathak KV; Bellamri M; Wang Y; Langouët S; Turesky RJ
    J Biol Chem; 2015 Jun; 290(26):16304-18. PubMed ID: 25953894
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA adducts of the tobacco carcinogens 2-amino-9H-pyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes.
    Nauwelaërs G; Bellamri M; Fessard V; Turesky RJ; Langouët S
    Chem Res Toxicol; 2013 Sep; 26(9):1367-77. PubMed ID: 23898916
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts.
    Bendaly J; Metry KJ; Doll MA; Jiang G; States JC; Smith NB; Neale JR; Holloman JL; Pierce WM; Hein DW
    Xenobiotica; 2009 May; 39(5):399-406. PubMed ID: 19301197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. UDP-glucuronosyltransferase-mediated metabolic activation of the tobacco carcinogen 2-amino-9H-pyrido[2,3-b]indole.
    Tang Y; LeMaster DM; Nauwelaërs G; Gu D; Langouët S; Turesky RJ
    J Biol Chem; 2012 Apr; 287(18):14960-72. PubMed ID: 22393056
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of Mice.
    Turesky RJ; Konorev D; Fan X; Tang Y; Yao L; Ding X; Xie F; Zhu Y; Zhang QY
    Chem Res Toxicol; 2015 Dec; 28(12):2400-10. PubMed ID: 26583703
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes.
    Habil MR; Salazar-González RA; Doll MA; Hein DW
    Arch Toxicol; 2022 Nov; 96(11):2999-3012. PubMed ID: 36040704
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).
    Metry KJ; Neale JR; Doll MA; Howarth AL; States JC; McGregor WG; Pierce WM; Hein DW
    Mutat Res; 2010 Feb; 684(1-2):66-73. PubMed ID: 20004212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and identification of DNA adducts in organs from rats dosed with MeAalphaC.
    Frederiksen H; Frandsen H; Pfau W
    Carcinogenesis; 2004 Aug; 25(8):1525-33. PubMed ID: 15059926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantification of Hemoglobin and White Blood Cell DNA Adducts of the Tobacco Carcinogens 2-Amino-9H-pyrido[2,3-b]indole and 4-Aminobiphenyl Formed in Humans by Nanoflow Liquid Chromatography/Ion Trap Multistage Mass Spectrometry.
    Cai T; Bellamri M; Ming X; Koh WP; Yu MC; Turesky RJ
    Chem Res Toxicol; 2017 Jun; 30(6):1333-1343. PubMed ID: 28493705
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells.
    Bellamri M; Yao L; Bonala R; Johnson F; Von Weymarn LB; Turesky RJ
    Arch Toxicol; 2019 Jul; 93(7):1893-1902. PubMed ID: 31203411
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress.
    Habil MR; Salazar-González RA; Doll MA; Hein DW
    Arch Toxicol; 2023 Jun; 97(6):1773-1781. PubMed ID: 37142755
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bioactivation of Heterocyclic Aromatic Amines by UDP Glucuronosyltransferases.
    Cai T; Yao L; Turesky RJ
    Chem Res Toxicol; 2016 May; 29(5):879-91. PubMed ID: 27032077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.
    Bellamri M; Le Hegarat L; Vernhet L; Baffet G; Turesky RJ; Langouët S
    Environ Mol Mutagen; 2016 Dec; 57(9):656-667. PubMed ID: 27801952
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
    Glatt H; Pabel U; Meinl W; Frederiksen H; Frandsen H; Muckel E
    Carcinogenesis; 2004 May; 25(5):801-7. PubMed ID: 14729582
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.