BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 19245217)

  • 1. Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2.
    Matthews ML; Krest CM; Barr EW; Vaillancourt FH; Walsh CT; Green MT; Krebs C; Bollinger JM
    Biochemistry; 2009 May; 48(20):4331-43. PubMed ID: 19245217
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase.
    Vaillancourt FH; Yin J; Walsh CT
    Proc Natl Acad Sci U S A; 2005 Jul; 102(29):10111-6. PubMed ID: 16002467
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2.
    Matthews ML; Neumann CS; Miles LA; Grove TL; Booker SJ; Krebs C; Walsh CT; Bollinger JM
    Proc Natl Acad Sci U S A; 2009 Oct; 106(42):17723-8. PubMed ID: 19815524
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First-principles study of non-heme Fe(II) halogenase SyrB2 reactivity.
    Kulik HJ; Blasiak LC; Marzari N; Drennan CL
    J Am Chem Soc; 2009 Oct; 131(40):14426-33. PubMed ID: 19807187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Experimental Correlation of Substrate Position with Reaction Outcome in the Aliphatic Halogenase, SyrB2.
    Martinie RJ; Livada J; Chang WC; Green MT; Krebs C; Bollinger JM; Silakov A
    J Am Chem Soc; 2015 Jun; 137(21):6912-9. PubMed ID: 25965587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.
    Blasiak LC; Vaillancourt FH; Walsh CT; Drennan CL
    Nature; 2006 Mar; 440(7082):368-71. PubMed ID: 16541079
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes.
    Martinie RJ; Pollock CJ; Matthews ML; Bollinger JM; Krebs C; Silakov A
    Inorg Chem; 2017 Nov; 56(21):13382-13389. PubMed ID: 28960972
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nuclear Resonance Vibrational Spectroscopic Definition of the Facial Triad Fe
    Srnec M; Iyer SR; Dassama LMK; Park K; Wong SD; Sutherlin KD; Yoda Y; Kobayashi Y; Kurokuzu M; Saito M; Seto M; Krebs C; Bollinger JM; Solomon EI
    J Am Chem Soc; 2020 Nov; 142(44):18886-18896. PubMed ID: 33103886
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Electronic Structure of the Ferryl Intermediate in the α-Ketoglutarate Dependent Non-Heme Iron Halogenase SyrB2: Contributions to H Atom Abstraction Reactivity.
    Srnec M; Wong SD; Matthews ML; Krebs C; Bollinger JM; Solomon EI
    J Am Chem Soc; 2016 Apr; 138(15):5110-22. PubMed ID: 27021969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elucidation of the Fe(IV)=O intermediate in the catalytic cycle of the halogenase SyrB2.
    Wong SD; Srnec M; Matthews ML; Liu LV; Kwak Y; Park K; Bell CB; Alp EE; Zhao J; Yoda Y; Kitao S; Seto M; Krebs C; Bollinger JM; Solomon EI
    Nature; 2013 Jul; 499(7458):320-3. PubMed ID: 23868262
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase.
    Matthews ML; Chang WC; Layne AP; Miles LA; Krebs C; Bollinger JM
    Nat Chem Biol; 2014 Mar; 10(3):209-15. PubMed ID: 24463698
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3.
    Galonić DP; Barr EW; Walsh CT; Bollinger JM; Krebs C
    Nat Chem Biol; 2007 Feb; 3(2):113-6. PubMed ID: 17220900
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Formation and structure of the ferryl [Fe[double bond, length as m-dash]O] intermediate in the non-haem iron halogenase SyrB2: classical and QM/MM modelling agree.
    Rugg G; Senn HM
    Phys Chem Chem Phys; 2017 Nov; 19(44):30107-30119. PubMed ID: 29099125
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine --Thr3 from Streptomyces sp. OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR.
    Fullone MR; Paiardini A; Miele R; Marsango S; Gross DC; Omura S; Ros-Herrera E; Bonaccorsi di Patti MC; Laganà A; Pascarella S; Grgurina I
    FEBS J; 2012 Dec; 279(23):4269-82. PubMed ID: 23025743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate.
    Grzyska PK; Ryle MJ; Monterosso GR; Liu J; Ballou DP; Hausinger RP
    Biochemistry; 2005 Mar; 44(10):3845-55. PubMed ID: 15751960
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of SyrC, an aminoacyltransferase shuttling threonyl and chlorothreonyl residues in the syringomycin biosynthetic assembly line.
    Singh GM; Vaillancourt FH; Yin J; Walsh CT
    Chem Biol; 2007 Jan; 14(1):31-40. PubMed ID: 17254950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of selective halogenation by SyrB2: a computational study.
    Borowski T; Noack H; Radoń M; Zych K; Siegbahn PE
    J Am Chem Soc; 2010 Sep; 132(37):12887-98. PubMed ID: 20738087
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stopped-flow kinetic analysis of Escherichia coli taurine/alpha-ketoglutarate dioxygenase: interactions with alpha-ketoglutarate, taurine, and oxygen.
    Ryle MJ; Padmakumar R; Hausinger RP
    Biochemistry; 1999 Nov; 38(46):15278-86. PubMed ID: 10563813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for Modulation of Oxygen Rebound Rate in Control of Outcome by Iron(II)- and 2-Oxoglutarate-Dependent Oxygenases.
    Pan J; Wenger ES; Matthews ML; Pollock CJ; Bhardwaj M; Kim AJ; Allen BD; Grossman RB; Krebs C; Bollinger JM
    J Am Chem Soc; 2019 Sep; 141(38):15153-15165. PubMed ID: 31475820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.
    Hangasky JA; Taabazuing CY; Valliere MA; Knapp MJ
    Metallomics; 2013 Apr; 5(4):287-301. PubMed ID: 23446356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.