BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 19245835)

  • 1. The human ATR-mediated DNA damage checkpoint in a reconstituted system.
    Choi JH; Sancar A; Lindsey-Boltz LA
    Methods; 2009 May; 48(1):3-7. PubMed ID: 19245835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
    Lindsey-Boltz LA; Sancar A
    J Biol Chem; 2011 Jun; 286(22):19229-36. PubMed ID: 21502314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.
    Ohashi E; Takeishi Y; Ueda S; Tsurimoto T
    DNA Repair (Amst); 2014 Sep; 21():1-11. PubMed ID: 25091155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reconstitution of a human ATR-mediated checkpoint response to damaged DNA.
    Choi JH; Lindsey-Boltz LA; Sancar A
    Proc Natl Acad Sci U S A; 2007 Aug; 104(33):13301-6. PubMed ID: 17686975
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATRIP from TopBP1 to ATR--in vitro activation of a DNA damage checkpoint.
    Xu YJ; Leffak M
    Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13561-2. PubMed ID: 20660767
    [No Abstract]   [Full Text] [Related]  

  • 6. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.
    Choi JH; Lindsey-Boltz LA; Kemp M; Mason AC; Wold MS; Sancar A
    Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13660-5. PubMed ID: 20616048
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation.
    Liu S; Bekker-Jensen S; Mailand N; Lukas C; Bartek J; Lukas J
    Mol Cell Biol; 2006 Aug; 26(16):6056-64. PubMed ID: 16880517
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses.
    Yoo HY; Shevchenko A; Shevchenko A; Dunphy WG
    J Biol Chem; 2004 Dec; 279(51):53353-64. PubMed ID: 15448142
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase.
    Lindsey-Boltz LA; Serçin O; Choi JH; Sancar A
    J Biol Chem; 2009 Nov; 284(48):33107-14. PubMed ID: 19828454
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HCLK2 is required for activity of the DNA damage response kinase ATR.
    Rendtlew Danielsen JM; Larsen DH; Schou KB; Freire R; Falck J; Bartek J; Lukas J
    J Biol Chem; 2009 Feb; 284(7):4140-7. PubMed ID: 19097996
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA.
    Choi JH; Lindsey-Boltz LA; Sancar A
    Nucleic Acids Res; 2009 Apr; 37(5):1501-9. PubMed ID: 19139065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.
    Liu Y; Fang Y; Shao H; Lindsey-Boltz L; Sancar A; Modrich P
    J Biol Chem; 2010 Feb; 285(8):5974-82. PubMed ID: 20029092
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response.
    Hassan BH; Lindsey-Boltz LA; Kemp MG; Sancar A
    J Biol Chem; 2013 Jun; 288(26):18903-10. PubMed ID: 23696651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATR autophosphorylation as a molecular switch for checkpoint activation.
    Liu S; Shiotani B; Lahiri M; Maréchal A; Tse A; Leung CC; Glover JN; Yang XH; Zou L
    Mol Cell; 2011 Jul; 43(2):192-202. PubMed ID: 21777809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.
    Sivasubramaniam S; Sun X; Pan YR; Wang S; Lee EY
    Genes Dev; 2008 Mar; 22(5):587-600. PubMed ID: 18283122
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of ATRIP protein abundance by RAD9 in the DNA damage repair pathway.
    Peng XJ; Liu SJ; Bao CM; Liu YZ; Xie HW; Cai YH; Li BM; Hang HY; Ding X
    Cell Mol Biol (Noisy-le-grand); 2015 Dec; 61(8):31-6. PubMed ID: 26667770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
    Liu K; Graves JD; Lin FT; Lin WC
    J Biol Chem; 2021; 296():100382. PubMed ID: 33556369
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NBS1 directly activates ATR independently of MRE11 and TOPBP1.
    Kobayashi M; Hayashi N; Takata M; Yamamoto K
    Genes Cells; 2013 Mar; 18(3):238-46. PubMed ID: 23368512
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
    Falck J; Coates J; Jackson SP
    Nature; 2005 Mar; 434(7033):605-11. PubMed ID: 15758953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
    Kemp MG; Akan Z; Yilmaz S; Grillo M; Smith-Roe SL; Kang TH; Cordeiro-Stone M; Kaufmann WK; Abraham RT; Sancar A; Unsal-Kaçmaz K
    J Biol Chem; 2010 May; 285(22):16562-71. PubMed ID: 20233725
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.