BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 19246514)

  • 1. Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha.
    Malakauskas SM; Kourany WM; Zhang XY; Lu D; Stevens RD; Koves TR; Hohmeier HE; Muoio DM; Newgard CB; Le TH
    Mol Endocrinol; 2009 Jun; 23(6):881-92. PubMed ID: 19246514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation.
    Fukui K; Yang Q; Cao Y; Takahashi N; Hatakeyama H; Wang H; Wada J; Zhang Y; Marselli L; Nammo T; Yoneda K; Onishi M; Higashiyama S; Matsuzawa Y; Gonzalez FJ; Weir GC; Kasai H; Shimomura I; Miyagawa J; Wollheim CB; Yamagata K
    Cell Metab; 2005 Dec; 2(6):373-84. PubMed ID: 16330323
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation.
    Akpinar P; Kuwajima S; Krützfeldt J; Stoffel M
    Cell Metab; 2005 Dec; 2(6):385-97. PubMed ID: 16330324
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The HNF-1alpha-SNARE connection.
    Yamagata K; Nammo T; Sato Y; Saisho K; Shoda H; Fukui K
    Diabetes Obes Metab; 2007 Nov; 9 Suppl 2():40-5. PubMed ID: 17919177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.
    Pongratz RL; Kibbey RG; Kirkpatrick CL; Zhao X; Pontoglio M; Yaniv M; Wollheim CB; Shulman GI; Cline GW
    J Biol Chem; 2009 Jun; 284(25):16808-16821. PubMed ID: 19376774
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.
    Shih DQ; Heimesaat M; Kuwajima S; Stein R; Wright CV; Stoffel M
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3818-23. PubMed ID: 11904435
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatocyte nuclear factor-1alpha modulates pancreatic beta-cell growth by regulating the expression of insulin-like growth factor-1 in INS-1 cells.
    Yang Q; Yamagata K; Fukui K; Cao Y; Nammo T; Iwahashi H; Wang H; Matsumura I; Hanafusa T; Bucala R; Wollheim CB; Miyagawa J; Matsuzawa Y
    Diabetes; 2002 Jun; 51(6):1785-92. PubMed ID: 12031966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
    Pontoglio M; Sreenan S; Roe M; Pugh W; Ostrega D; Doyen A; Pick AJ; Baldwin A; Velho G; Froguel P; Levisetti M; Bonner-Weir S; Bell GI; Yaniv M; Polonsky KS
    J Clin Invest; 1998 May; 101(10):2215-22. PubMed ID: 9593777
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Collectrin (
    Chu PL; Gigliotti JC; Cechova S; Bodonyi-Kovacs G; Wang YT; Chen L; Wassertheil-Smoller S; Cai J; Isakson BE; Franceschini N; Le TH
    Am J Physiol Renal Physiol; 2023 Jan; 324(1):F30-F42. PubMed ID: 36264884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.
    Wang H; Maechler P; Hagenfeldt KA; Wollheim CB
    EMBO J; 1998 Nov; 17(22):6701-13. PubMed ID: 9822613
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.
    Shih DQ; Screenan S; Munoz KN; Philipson L; Pontoglio M; Yaniv M; Polonsky KS; Stoffel M
    Diabetes; 2001 Nov; 50(11):2472-80. PubMed ID: 11679424
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.
    Ahrén B; Sörhede Winzell M; Burkey B; Hughes TE
    Eur J Pharmacol; 2005 Oct; 521(1-3):164-8. PubMed ID: 16171801
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.
    Yamagata K; Nammo T; Moriwaki M; Ihara A; Iizuka K; Yang Q; Satoh T; Li M; Uenaka R; Okita K; Iwahashi H; Zhu Q; Cao Y; Imagawa A; Tochino Y; Hanafusa T; Miyagawa J; Matsuzawa Y
    Diabetes; 2002 Jan; 51(1):114-23. PubMed ID: 11756330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).
    Boileau P; Wolfrum C; Shih DQ; Yang TA; Wolkoff AW; Stoffel M
    Diabetes; 2002 Dec; 51 Suppl 3():S343-8. PubMed ID: 12475773
    [TBL] [Abstract][Full Text] [Related]  

  • 15. beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations.
    Pearson ER; Velho G; Clark P; Stride A; Shepherd M; Frayling TM; Bulman MP; Ellard S; Froguel P; Hattersley AT
    Diabetes; 2001 Feb; 50 Suppl 1():S101-7. PubMed ID: 11272165
    [TBL] [Abstract][Full Text] [Related]  

  • 16. G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction.
    Holst B; Egerod KL; Jin C; Petersen PS; Østergaard MV; Hald J; Sprinkel AM; Størling J; Mandrup-Poulsen T; Holst JJ; Thams P; Orskov C; Wierup N; Sundler F; Madsen OD; Schwartz TW
    Endocrinology; 2009 Jun; 150(6):2577-85. PubMed ID: 19213833
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY).
    Yamagata K
    Vitam Horm; 2014; 95():407-23. PubMed ID: 24559927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HNF1α controls glucagon secretion in pancreatic α-cells through modulation of SGLT1.
    Sato Y; Rahman MM; Haneda M; Tsuyama T; Mizumoto T; Yoshizawa T; Kitamura T; Gonzalez FJ; Yamamura KI; Yamagata K
    Biochim Biophys Acta Mol Basis Dis; 2020 Nov; 1866(11):165898. PubMed ID: 32711050
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of transmembrane protein 27 (TMEM27) in islet physiology and its potential use as a beta cell mass biomarker.
    Altirriba J; Gasa R; Casas S; Ramírez-Bajo MJ; Ros S; Gutierrez-Dalmau A; Ruiz de Villa MC; Barbera A; Gomis R
    Diabetologia; 2010 Jul; 53(7):1406-14. PubMed ID: 20386877
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II.
    Chu PL; Gigliotti JC; Cechova S; Bodonyi-Kovacs G; Chan F; Ralph DL; Howell N; Kalantari K; Klibanov AL; Carey RM; McDonough AA; Le TH
    J Am Soc Nephrol; 2017 Jun; 28(6):1826-1837. PubMed ID: 28062568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.