305 related articles for article (PubMed ID: 19246624)
1. Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.
Reisman SA; Csanaky IL; Aleksunes LM; Klaassen CD
Toxicol Sci; 2009 May; 109(1):31-40. PubMed ID: 19246624
[TBL] [Abstract][Full Text] [Related]
2. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.
Reisman SA; Yeager RL; Yamamoto M; Klaassen CD
Toxicol Sci; 2009 Mar; 108(1):35-47. PubMed ID: 19129213
[TBL] [Abstract][Full Text] [Related]
3. Nrf2 activation enhances biliary excretion of sulfobromophthalein by inducing glutathione-S-transferase activity.
Reisman SA; Csanaky IL; Yeager RL; Klaassen CD
Toxicol Sci; 2009 May; 109(1):24-30. PubMed ID: 19246623
[TBL] [Abstract][Full Text] [Related]
4. The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system.
Copple IM; Goldring CE; Jenkins RE; Chia AJ; Randle LE; Hayes JD; Kitteringham NR; Park BK
Hepatology; 2008 Oct; 48(4):1292-301. PubMed ID: 18785192
[TBL] [Abstract][Full Text] [Related]
5. Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1.
Cheng Q; Taguchi K; Aleksunes LM; Manautou JE; Cherrington NJ; Yamamoto M; Slitt AL
J Biochem Mol Toxicol; 2011; 25(5):320-9. PubMed ID: 21538727
[TBL] [Abstract][Full Text] [Related]
6. Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet.
Zhang YK; Yeager RL; Tanaka Y; Klaassen CD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):326-34. PubMed ID: 20350562
[TBL] [Abstract][Full Text] [Related]
7. Nrf2 protects against furosemide-induced hepatotoxicity.
Qu Q; Liu J; Zhou HH; Klaassen CD
Toxicology; 2014 Oct; 324():35-42. PubMed ID: 24813929
[TBL] [Abstract][Full Text] [Related]
8. Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation.
Kim S; Lee HG; Park SA; Kundu JK; Keum YS; Cha YN; Na HK; Surh YJ
PLoS One; 2014; 9(1):e85984. PubMed ID: 24489685
[TBL] [Abstract][Full Text] [Related]
9. Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system.
Pang C; Zheng Z; Shi L; Sheng Y; Wei H; Wang Z; Ji L
Free Radic Biol Med; 2016 Feb; 91():236-46. PubMed ID: 26721592
[TBL] [Abstract][Full Text] [Related]
10. Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems.
Okada K; Shoda J; Taguchi K; Maher JM; Ishizaki K; Inoue Y; Ohtsuki M; Goto N; Sugimoto H; Utsunomiya H; Oda K; Warabi E; Ishii T; Yamamoto M
Biochem Biophys Res Commun; 2009 Nov; 389(3):431-6. PubMed ID: 19732748
[TBL] [Abstract][Full Text] [Related]
11. Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver.
Wu KC; Cui JY; Klaassen CD
PLoS One; 2012; 7(7):e39006. PubMed ID: 22808024
[TBL] [Abstract][Full Text] [Related]
12. Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.
Xu J; Kulkarni SR; Donepudi AC; More VR; Slitt AL
Diabetes; 2012 Dec; 61(12):3208-18. PubMed ID: 22936178
[TBL] [Abstract][Full Text] [Related]
13. Nrf2 protects against diquat-induced liver and lung injury.
Wu KC; Zhang Y; Klaassen CD
Free Radic Res; 2012 Oct; 46(10):1220-9. PubMed ID: 22762311
[TBL] [Abstract][Full Text] [Related]
14. NAD(P)H:quinone oxidoreductase 1 activity reduces hypertrophy in 3T3-L1 adipocytes.
Vomhof-DeKrey EE; Picklo MJ
Free Radic Biol Med; 2012 Aug; 53(4):690-700. PubMed ID: 22683604
[TBL] [Abstract][Full Text] [Related]
15. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.
Aleksunes LM; Slitt AL; Maher JM; Augustine LM; Goedken MJ; Chan JY; Cherrington NJ; Klaassen CD; Manautou JE
Toxicol Appl Pharmacol; 2008 Jan; 226(1):74-83. PubMed ID: 17935745
[TBL] [Abstract][Full Text] [Related]
16. Glucose availability is a decisive factor for Nrf2-mediated gene expression.
Heiss EH; Schachner D; Zimmermann K; Dirsch VM
Redox Biol; 2013; 1(1):359-65. PubMed ID: 24024172
[TBL] [Abstract][Full Text] [Related]
17. Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.
Okada K; Shoda J; Taguchi K; Maher JM; Ishizaki K; Inoue Y; Ohtsuki M; Goto N; Takeda K; Utsunomiya H; Oda K; Warabi E; Ishii T; Osaka K; Hyodo I; Yamamoto M
Am J Physiol Gastrointest Liver Physiol; 2008 Oct; 295(4):G735-47. PubMed ID: 18687751
[TBL] [Abstract][Full Text] [Related]
18. Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone.
Miura T; Shinkai Y; Jiang HY; Iwamoto N; Sumi D; Taguchi K; Yamamoto M; Jinno H; Tanaka-Kagawa T; Cho AK; Kumagai Y
Chem Res Toxicol; 2011 Apr; 24(4):559-67. PubMed ID: 21384861
[TBL] [Abstract][Full Text] [Related]
19. Keap1 inhibition attenuates glomerulosclerosis.
Miyazaki Y; Shimizu A; Pastan I; Taguchi K; Naganuma E; Suzuki T; Hosoya T; Yokoo T; Saito A; Miyata T; Yamamoto M; Matsusaka T
Nephrol Dial Transplant; 2014 Apr; 29(4):783-91. PubMed ID: 24523358
[TBL] [Abstract][Full Text] [Related]
20. Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.
He X; Chen MG; Lin GX; Ma Q
J Biol Chem; 2006 Aug; 281(33):23620-31. PubMed ID: 16785233
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
