BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 19247496)

  • 1. Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice.
    Gogishvili T; Langenhorst D; Lühder F; Elias F; Elflein K; Dennehy KM; Gold R; Hünig T
    PLoS One; 2009; 4(2):e4643. PubMed ID: 19247496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08.
    Tabares P; Berr S; Römer PS; Chuvpilo S; Matskevich AA; Tyrsin D; Fedotov Y; Einsele H; Tony HP; Hünig T
    Eur J Immunol; 2014 Apr; 44(4):1225-36. PubMed ID: 24374661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats.
    Miyasato K; Takabatake Y; Kaimori J; Kimura T; Kitamura H; Kawachi H; Li XK; Hünig T; Takahara S; Rakugi H; Isaka Y
    Clin Exp Nephrol; 2011 Feb; 15(1):50-7. PubMed ID: 21076989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CD28 signals the differential control of regulatory T cells and effector T cells.
    Mikami N; Sakaguchi S
    Eur J Immunol; 2014 Apr; 44(4):955-7. PubMed ID: 24652756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice.
    Win SJ; Kühl AA; Sparwasser T; Hünig T; Kamradt T
    Eur J Immunol; 2016 May; 46(5):1193-202. PubMed ID: 26711629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Superagonistic CD28 Protects against Renal Ischemic Injury by Expansion of Regulatory T-Cell.
    Liang Y; Li Y; Kuang Q; Ding X; Wei Z; Fang Y
    Am J Nephrol; 2017; 45(5):389-399. PubMed ID: 28355607
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Self-Recognition Sensitizes Mouse and Human Regulatory T Cells to Low-Dose CD28 Superagonist Stimulation.
    Langenhorst D; Tabares P; Gulde T; Becklund BR; Berr S; Surh CD; Beyersdorf N; Hünig T
    Front Immunol; 2017; 8():1985. PubMed ID: 29441059
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
    Thaventhiran T; Alhumeed N; Yeang HX; Sethu S; Downey JS; Alghanem AF; Olayanju A; Smith EL; Cross MJ; Webb SD; Williams DP; Bristow A; Ball C; Stebbings R; Sathish JG
    MAbs; 2014; 6(5):1290-9. PubMed ID: 25517314
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signaling signatures and functional properties of anti-human CD28 superagonistic antibodies.
    Waibler Z; Sender LY; Merten C; Hartig R; Kliche S; Gunzer M; Reichardt P; Kalinke U; Schraven B
    PLoS One; 2008 Mar; 3(3):e1708. PubMed ID: 18320029
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells.
    He X; Smeets RL; van Rijssen E; Boots AM; Joosten I; Koenen HJ
    Sci Rep; 2017 Feb; 7():43003. PubMed ID: 28223693
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.
    Römer PS; Berr S; Avota E; Na SY; Battaglia M; ten Berge I; Einsele H; Hünig T
    Blood; 2011 Dec; 118(26):6772-82. PubMed ID: 21931118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice.
    Na SY; Mracsko E; Liesz A; Hünig T; Veltkamp R
    Stroke; 2015 Jan; 46(1):212-20. PubMed ID: 25378432
    [TBL] [Abstract][Full Text] [Related]  

  • 13. From TGN1412 to TAB08: the return of CD28 superagonist therapy to clinical development for the treatment of rheumatoid arthritis.
    Tyrsin D; Chuvpilo S; Matskevich A; Nemenov D; Römer PS; Tabares P; Hünig T
    Clin Exp Rheumatol; 2016; 34(4 Suppl 98):45-8. PubMed ID: 27586803
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective expansion of memory CD4(+) T cells by mitogenic human CD28 generates inflammatory cytokines and regulatory T cells.
    Singh M; Basu S; Camell C; Couturier J; Nudelman RJ; Medina MA; Rodgers JR; Lewis DE
    Eur J Immunol; 2008 Jun; 38(6):1522-32. PubMed ID: 18446791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The rise and fall of the CD28 superagonist TGN1412 and its return as TAB08: a personal account.
    Hünig T
    FEBS J; 2016 Sep; 283(18):3325-34. PubMed ID: 27191544
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Advantages of Papio anubis for preclinical testing of immunotoxicity of candidate therapeutic antagonist antibodies targeting CD28.
    Poirier N; Mary C; Le Bas-Bernardet S; Daguin V; Belarif L; Chevalier M; Hervouet J; Minault D; Ville S; Charpy V; Blancho G; Vanhove B
    MAbs; 2014; 6(3):697-707. PubMed ID: 24598534
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential induction of effector function, tissue migration and cell death during polyclonal activation of mouse regulatory T-cells.
    Langenhorst D; Gogishvili T; Ribechini E; Kneitz S; McPherson K; Lutz MB; Hünig T
    PLoS One; 2012; 7(11):e50080. PubMed ID: 23226238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expansion of regulatory T cells by CD28 superagonistic antibodies attenuates neurodegeneration in A53T-α-synuclein Parkinson's disease mice.
    Badr M; McFleder RL; Wu J; Knorr S; Koprich JB; Hünig T; Brotchie JM; Volkmann J; Lutz MB; Ip CW
    J Neuroinflammation; 2022 Dec; 19(1):319. PubMed ID: 36587195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells.
    Eastwood D; Findlay L; Poole S; Bird C; Wadhwa M; Moore M; Burns C; Thorpe R; Stebbings R
    Br J Pharmacol; 2010 Oct; 161(3):512-26. PubMed ID: 20880392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program.
    Thaventhiran T; Wong W; Alghanem AF; Alhumeed N; Aljasir MA; Ramsey S; Sethu S; Yeang HXA; Chadwick AE; Cross M; Webb SD; Djouhri L; Ball C; Stebbings R; Sathish JG
    Monoclon Antib Immunodiagn Immunother; 2019 Apr; 38(2):60-69. PubMed ID: 31009338
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.