BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 19248225)

  • 1. Activation of PPARalpha and PPARgamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1.
    König B; Koch A; Spielmann J; Hilgenfeld C; Hirche F; Stangl GI; Eder K
    Eur J Pharmacol; 2009 Mar; 605(1-3):23-30. PubMed ID: 19248225
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of PPARalpha lowers synthesis and concentration of cholesterol by reduction of nuclear SREBP-2.
    König B; Koch A; Spielmann J; Hilgenfeld C; Stangl GI; Eder K
    Biochem Pharmacol; 2007 Feb; 73(4):574-85. PubMed ID: 17126302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells.
    Risé P; Ghezzi S; Carissimi R; Mastromauro F; Petroni A; Galli C
    Eur J Pharmacol; 2007 Oct; 571(2-3):97-105. PubMed ID: 17655842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation.
    Lelliott CJ; Ljungberg A; Ahnmark A; William-Olsson L; Ekroos K; Elmgren A; Arnerup G; Shoulders CC; Oscarsson J; Lindén D
    Arterioscler Thromb Vasc Biol; 2007 Dec; 27(12):2707-13. PubMed ID: 17932310
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PPAR gamma ligand troglitazone lowers cholesterol synthesis in HepG2 and Caco-2 cells via a reduced concentration of nuclear SREBP-2.
    Klopotek A; Hirche F; Eder K
    Exp Biol Med (Maywood); 2006 Sep; 231(8):1365-72. PubMed ID: 16946405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.
    Yellaturu CR; Deng X; Park EA; Raghow R; Elam MB
    J Biol Chem; 2009 Nov; 284(46):31726-34. PubMed ID: 19759400
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding protein in the regulation of adipogenesis.
    Kast-Woelbern HR; Dana SL; Cesario RM; Sun L; de Grandpre LY; Brooks ME; Osburn DL; Reifel-Miller A; Klausing K; Leibowitz MD
    J Biol Chem; 2004 Jun; 279(23):23908-15. PubMed ID: 15073165
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel processing system of sterol regulatory element-binding protein-1c regulated by polyunsaturated fatty acid.
    Nakakuki M; Kawano H; Notsu T; Imada K; Mizuguchi K; Shimano H
    J Biochem; 2014 May; 155(5):301-13. PubMed ID: 24729033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid.
    Tong X; Christian P; Zhao M; Wang H; Moreau R; Su Q
    J Nutr Biochem; 2015 Sep; 26(9):921-8. PubMed ID: 26007286
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dietary α-lactalbumin induced fatty liver by enhancing nuclear liver X receptor αβ/sterol regulatory element-binding protein-1c/PPARγ expression and minimising PPARα/carnitine palmitoyltransferase-1 expression and AMP-activated protein kinase α phosphorylation associated with atherogenic dyslipidaemia, insulin resistance and oxidative stress in Balb/c mice.
    López-Oliva ME; Garcimartin A; Muñoz-Martínez E
    Br J Nutr; 2017 Dec; 118(11):914-929. PubMed ID: 29173234
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PPARα, PPARγ and SREBP-1 pathways mediated waterborne iron (Fe)-induced reduction in hepatic lipid deposition of javelin goby Synechogobius hasta.
    Chen GH; Luo Z; Chen F; Shi X; Song YF; You WJ; Liu X
    Comp Biochem Physiol C Toxicol Pharmacol; 2017 Jul; 197():8-18. PubMed ID: 28411055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Urokinase-type plasminogen activator (uPA) stimulates triglyceride synthesis in Huh7 hepatoma cells via p38-dependent upregulation of DGAT2.
    Paland N; Gamliel-Lazarovich A; Coleman R; Fuhrman B
    Atherosclerosis; 2014 Nov; 237(1):200-7. PubMed ID: 25244504
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes.
    Schadinger SE; Bucher NL; Schreiber BM; Farmer SR
    Am J Physiol Endocrinol Metab; 2005 Jun; 288(6):E1195-205. PubMed ID: 15644454
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in rat hepatocytes.
    Rogue A; Renaud MP; Claude N; Guillouzo A; Spire C
    Toxicol Appl Pharmacol; 2011 Jul; 254(1):18-31. PubMed ID: 21515302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Silibinin protects β cells from glucotoxicity through regulation of the Insig-1/SREBP-1c pathway.
    Chen K; Zhao L; He H; Wan X; Wang F; Mo Z
    Int J Mol Med; 2014 Oct; 34(4):1073-80. PubMed ID: 25109869
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver.
    Knight BL; Hebbachi A; Hauton D; Brown AM; Wiggins D; Patel DD; Gibbons GF
    Biochem J; 2005 Jul; 389(Pt 2):413-21. PubMed ID: 15777286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparison of in vivo effects of insulin on SREBP-1c activation and INSIG-1/2 in rat liver and human and rat adipose tissue.
    Boden G; Salehi S; Cheung P; Homko C; Song W; Loveland-Jones C; Jayarajan S
    Obesity (Silver Spring); 2013 Jun; 21(6):1208-14. PubMed ID: 23913732
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phenyllactic Acid from Lactobacillus plantarum PromotesAdipogenic Activity in 3T3-L1 Adipocyte via Up-Regulationof PPAR-γ2.
    Ilavenil S; Kim DH; Valan Arasu M; Srigopalram S; Sivanesan R; Choi KC
    Molecules; 2015 Aug; 20(8):15359-73. PubMed ID: 26305241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential effects of contraction and PPAR agonists on the expression of fatty acid transporters in rat skeletal muscle.
    Benton CR; Koonen DP; Calles-Escandon J; Tandon NN; Glatz JF; Luiken JJ; Heikkila JJ; Bonen A
    J Physiol; 2006 May; 573(Pt 1):199-210. PubMed ID: 16484294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer.
    Mansour M; Schwartz D; Judd R; Akingbemi B; Braden T; Morrison E; Dennis J; Bartol F; Hazi A; Napier I; Abdel-Mageed AB
    Int J Oncol; 2011 Feb; 38(2):537-46. PubMed ID: 21170507
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.