BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 19250825)

  • 21. Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model.
    La Motta C; Sartini S; Salerno S; Simorini F; Taliani S; Marini AM; Da Settimo F; Marinelli L; Limongelli V; Novellino E
    J Med Chem; 2008 Jun; 51(11):3182-93. PubMed ID: 18452283
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and aldose reductase inhibitory activities of novel thienocinnolinone derivatives.
    Pau A; Asproni B; Boatto G; Grella GE; De Caprariis P; Costantino L; Pinna GA
    Eur J Pharm Sci; 2004 Mar; 21(4):545-52. PubMed ID: 14998586
    [TBL] [Abstract][Full Text] [Related]  

  • 23. In vitro inhibition of lens aldose reductase by (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-yl)-acetic acid in enzyme preparations isolated from diabetic rats.
    Djoubissie PO; Snirc V; Sotnikova R; Zurova J; Kyselova Z; Skalska S; Gajdosik A; Javorkova V; Vlkovicova J; Vrbjar N; Stefek M
    Gen Physiol Biophys; 2006 Dec; 25(4):415-25. PubMed ID: 17356233
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor.
    Courtney SM; Hay PA; Buck RT; Colville CS; Phillips DJ; Scopes DI; Pollard FC; Page MJ; Bennett JM; Hircock ML; McKenzie EA; Bhaman M; Felix R; Stubberfield CR; Turner PR
    Bioorg Med Chem Lett; 2005 May; 15(9):2295-9. PubMed ID: 15837312
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications.
    Saraswat M; Muthenna P; Suryanarayana P; Petrash JM; Reddy GB
    Asia Pac J Clin Nutr; 2008; 17(4):558-65. PubMed ID: 19114390
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel quinazolinone-based 2,4-thiazolidinedione-3-acetic acid derivatives as potent aldose reductase inhibitors.
    Metwally K; Pratsinis H; Kletsas D; Quattrini L; Coviello V; Motta C; El-Rashedy AA; Soliman ME
    Future Med Chem; 2017 Dec; 9(18):2147-2166. PubMed ID: 29098865
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel, highly potent aldose reductase inhibitors: (R)-(-)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4- tetrahydropyrrolo[1,2-a]pyrazine -4-spiro-3'-pyrrolidine-1,2',3,5'-tetrone (AS-3201) and its congeners.
    Negoro T; Murata M; Ueda S; Fujitani B; Ono Y; Kuromiya A; Komiya M; Suzuki K; Matsumoto J
    J Med Chem; 1998 Oct; 41(21):4118-29. PubMed ID: 9767647
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Probing flexibility and "induced-fit" phenomena in aldose reductase by comparative crystal structure analysis and molecular dynamics simulations.
    Sotriffer CA; Krämer O; Klebe G
    Proteins; 2004 Jul; 56(1):52-66. PubMed ID: 15162486
    [TBL] [Abstract][Full Text] [Related]  

  • 29. (3R)-3-amino-4-(2,4,5-trifluorophenyl)-N-{4-[6-(2-methoxyethoxy)benzothiazol-2-yl]tetrahydropyran-4-yl}butanamide as a potent dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
    Nitta A; Fujii H; Sakami S; Nishimura Y; Ohyama T; Satoh M; Nakaki J; Satoh S; Inada C; Kozono H; Kumagai H; Shimamura M; Fukazawa T; Kawai H
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5435-8. PubMed ID: 18819797
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis of novel benzoic acid derivatives with benzothiazolyl subunit and evaluation as aldose reductase inhibitors.
    Rakowitz D; Hennig B; Nagano M; Steger S; Costantino L; Matuszczak B
    Arch Pharm (Weinheim); 2005 Sep; 338(9):411-8. PubMed ID: 16143954
    [TBL] [Abstract][Full Text] [Related]  

  • 31. (4-Oxo-2-thioxothiazolidin-3-yl)acetic acids as potent and selective aldose reductase inhibitors.
    Kucerova-Chlupacova M; Halakova D; Majekova M; Treml J; Stefek M; Soltesova Prnova M
    Chem Biol Interact; 2020 Dec; 332():109286. PubMed ID: 33038328
    [TBL] [Abstract][Full Text] [Related]  

  • 32. How reliable are current docking approaches for structure-based drug design? Lessons from aldose reductase.
    Zentgraf M; Steuber H; Koch C; La Motta C; Sartini S; Sotriffer CA; Klebe G
    Angew Chem Int Ed Engl; 2007; 46(19):3575-8. PubMed ID: 17394265
    [No Abstract]   [Full Text] [Related]  

  • 33. Curcumin analogs as potent aldose reductase inhibitors.
    Du ZY; Bao YD; Liu Z; Qiao W; Ma L; Huang ZS; Gu LQ; Chan AS
    Arch Pharm (Weinheim); 2006 Mar; 339(3):123-8. PubMed ID: 16528793
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and aldose reductase inhibitory activities of novel O-substituted hydroxyphenylacetic acid derivatives.
    Rakowitz D; Angerer H; Matuszczak B
    Arch Pharm (Weinheim); 2006 Oct; 339(10):547-58. PubMed ID: 17009299
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibitory effect of rhetsinine isolated from Evodia rutaecarpa on aldose reductase activity.
    Kato A; Yasuko H; Goto H; Hollinshead J; Nash RJ; Adachi I
    Phytomedicine; 2009 Mar; 16(2-3):258-61. PubMed ID: 17498942
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum.
    Koukoulitsa C; Zika C; Geromichalos GD; Demopoulos VJ; Skaltsa H
    Bioorg Med Chem; 2006 Mar; 14(5):1653-9. PubMed ID: 16249088
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Spirohydantoin derivatives of thiopyrano[2,3-b]pyridin-4(4H)-one as potent in vitro and in vivo aldose reductase inhibitors.
    Da Settimo F; Primofiore G; La Motta C; Salerno S; Novellino E; Greco G; Lavecchia A; Laneri S; Boldrini E
    Bioorg Med Chem; 2005 Jan; 13(2):491-9. PubMed ID: 15598571
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of novel aldose reductase inhibitors characterized by an alkoxy-substituted phenylacetic acid core.
    Rakowitz D; Gmeiner A; Matuszczak B
    Arch Pharm (Weinheim); 2006 Oct; 339(10):559-63. PubMed ID: 17009300
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Protein structure-based de novo design and synthesis of aldose reductase inhibitors.
    Iwata Y; Naito S; Itai A; Miyamoto S
    Drug Des Discov; 2001; 17(4):349-59. PubMed ID: 11765138
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design and synthesis of potent and multifunctional aldose reductase inhibitors based on quinoxalinones.
    Qin X; Hao X; Han H; Zhu S; Yang Y; Wu B; Hussain S; Parveen S; Jing C; Ma B; Zhu C
    J Med Chem; 2015 Feb; 58(3):1254-67. PubMed ID: 25602762
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.