These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 19251691)

  • 1. Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons.
    Hagen N; Van Veldhoven PP; Proia RL; Park H; Merrill AH; van Echten-Deckert G
    J Biol Chem; 2009 Apr; 284(17):11346-53. PubMed ID: 19251691
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of p38 mitogen-activated protein kinase and partial reactivation of the cell cycle by cis-4-methylsphingosine direct postmitotic neurons towards apoptosis.
    Naetzker S; Hagen N; Echten-Deckert G
    Genes Cells; 2006 Mar; 11(3):269-79. PubMed ID: 16483315
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate.
    Siow DL; Anderson CD; Berdyshev EV; Skobeleva A; Pitson SM; Wattenberg BW
    J Lipid Res; 2010 Sep; 51(9):2546-59. PubMed ID: 20386061
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha.
    Pettus BJ; Bielawski J; Porcelli AM; Reames DL; Johnson KR; Morrow J; Chalfant CE; Obeid LM; Hannun YA
    FASEB J; 2003 Aug; 17(11):1411-21. PubMed ID: 12890694
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator.
    Ter Braak M; Claas RF; Hegen B; Labocha S; Ferreirós N; Pfeilschifter J; Huwiler A; van Echten-Deckert G; Meyer Zu Heringdorf D
    Biochem Pharmacol; 2011 Mar; 81(5):617-25. PubMed ID: 21163254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Redistribution of sphingosine 1-phosphate by sphingosine kinase 2 contributes to lymphopenia.
    Sensken SC; Bode C; Nagarajan M; Peest U; Pabst O; Gräler MH
    J Immunol; 2010 Apr; 184(8):4133-42. PubMed ID: 20220090
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sphingosine kinase, sphingosine-1-phosphate, and apoptosis.
    Maceyka M; Payne SG; Milstien S; Spiegel S
    Biochim Biophys Acta; 2002 Dec; 1585(2-3):193-201. PubMed ID: 12531554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.
    Berdyshev EV; Gorshkova IA; Usatyuk P; Zhao Y; Saatian B; Hubbard W; Natarajan V
    Cell Signal; 2006 Oct; 18(10):1779-92. PubMed ID: 16529909
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism.
    Hagen N; Hans M; Hartmann D; Swandulla D; van Echten-Deckert G
    Cell Death Differ; 2011 Aug; 18(8):1356-65. PubMed ID: 21331079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts.
    van Echten-Deckert G; Schick A; Heinemann T; Schnieders B
    J Biol Chem; 1998 Sep; 273(36):23585-9. PubMed ID: 9722598
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sphingosine-1-phosphate lyase is involved in the differentiation of F9 embryonal carcinoma cells to primitive endoderm.
    Kihara A; Ikeda M; Kariya Y; Lee EY; Lee YM; Igarashi Y
    J Biol Chem; 2003 Apr; 278(16):14578-85. PubMed ID: 12584204
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells.
    Watson DG; Tonelli F; Alossaimi M; Williamson L; Chan E; Gorshkova I; Berdyshev E; Bittman R; Pyne NJ; Pyne S
    Cell Signal; 2013 Apr; 25(4):1011-7. PubMed ID: 23314175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.
    Zhao Y; Kalari SK; Usatyuk PV; Gorshkova I; He D; Watkins T; Brindley DN; Sun C; Bittman R; Garcia JG; Berdyshev EV; Natarajan V
    J Biol Chem; 2007 May; 282(19):14165-77. PubMed ID: 17379599
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.
    Cinq-Frais C; Coatrieux C; Grazide MH; Hannun YA; Nègre-Salvayre A; Salvayre R; Augé N
    Biochim Biophys Acta; 2013 Aug; 1831(8):1344-56. PubMed ID: 23651497
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.
    Adada MM; Canals D; Jeong N; Kelkar AD; Hernandez-Corbacho M; Pulkoski-Gross MJ; Donaldson JC; Hannun YA; Obeid LM
    FASEB J; 2015 Nov; 29(11):4654-69. PubMed ID: 26209696
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An oncogenic role for sphingosine kinase 2.
    Neubauer HA; Pham DH; Zebol JR; Moretti PA; Peterson AL; Leclercq TM; Chan H; Powell JA; Pitman MR; Samuel MS; Bonder CS; Creek DJ; Gliddon BL; Pitson SM
    Oncotarget; 2016 Oct; 7(40):64886-64899. PubMed ID: 27588496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Extracellular release of newly synthesized sphingosine-1-phosphate by cerebellar granule cells and astrocytes.
    Anelli V; Bassi R; Tettamanti G; Viani P; Riboni L
    J Neurochem; 2005 Mar; 92(5):1204-15. PubMed ID: 15715670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neurodegeneration Caused by S1P-Lyase Deficiency Involves Calcium-Dependent Tau Pathology and Abnormal Histone Acetylation.
    Alam S; Piazzesi A; Abd El Fatah M; Raucamp M; van Echten-Deckert G
    Cells; 2020 Sep; 9(10):. PubMed ID: 32998447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons.
    van Echten-Deckert G; Zschoche A; Bär T; Schmidt RR; Raths A; Heinemann T; Sandhoff K
    J Biol Chem; 1997 Jun; 272(25):15825-33. PubMed ID: 9188480
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells.
    Gratschev D; Löf C; Heikkilä J; Björkbom A; Sukumaran P; Hinkkanen A; Slotte JP; Törnquist K
    Endocrinology; 2009 Nov; 150(11):5125-34. PubMed ID: 19797403
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.