442 related articles for article (PubMed ID: 19251820)
21. A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes.
Sogame Y; Kitamura A; Yabuki M; Komuro S
Biopharm Drug Dispos; 2009 Nov; 30(8):476-84. PubMed ID: 19768675
[TBL] [Abstract][Full Text] [Related]
22. Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule.
Kaewmokul S; Chatsudthipong V; Evans KK; Dantzler WH; Wright SH
Am J Physiol Renal Physiol; 2003 Dec; 285(6):F1149-59. PubMed ID: 12944320
[TBL] [Abstract][Full Text] [Related]
23. In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1.
Li L; Song F; Tu M; Wang K; Zhao L; Wu X; Zhou H; Xia Z; Jiang H
Int J Pharm; 2014 Apr; 465(1-2):5-10. PubMed ID: 24530383
[TBL] [Abstract][Full Text] [Related]
24. Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.
Umehara K; Shirai N; Iwatsubo T; Noguchi K; Usui T; Kamimura H
Drug Metab Dispos; 2009 Aug; 37(8):1646-57. PubMed ID: 19439489
[TBL] [Abstract][Full Text] [Related]
25. Organic cation transporter 3: expression in failing and nonfailing human heart and functional characterization.
Solbach TF; Grube M; Fromm MF; Zolk O
J Cardiovasc Pharmacol; 2011 Oct; 58(4):409-17. PubMed ID: 21697722
[TBL] [Abstract][Full Text] [Related]
26. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
Ito S; Kusuhara H; Yokochi M; Toyoshima J; Inoue K; Yuasa H; Sugiyama Y
J Pharmacol Exp Ther; 2012 Feb; 340(2):393-403. PubMed ID: 22072731
[TBL] [Abstract][Full Text] [Related]
27. Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.
Kimura N; Masuda S; Katsura T; Inui K
Biochem Pharmacol; 2009 Apr; 77(8):1429-36. PubMed ID: 19426682
[TBL] [Abstract][Full Text] [Related]
28. Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
Umehara KI; Iwatsubo T; Noguchi K; Kamimura H
Xenobiotica; 2007 Jun; 37(6):618-34. PubMed ID: 17614008
[TBL] [Abstract][Full Text] [Related]
29. Sitagliptin attenuates metformin-mediated AMPK phosphorylation through inhibition of organic cation transporters.
Choi MK; Jin QR; Ahn SH; Bae MA; Song IS
Xenobiotica; 2010 Dec; 40(12):817-25. PubMed ID: 20863201
[TBL] [Abstract][Full Text] [Related]
30. Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small molecule survivin suppressant.
Minematsu T; Iwai M; Umehara K; Usui T; Kamimura H
Drug Metab Dispos; 2010 Jan; 38(1):1-4. PubMed ID: 19833842
[TBL] [Abstract][Full Text] [Related]
31. Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs).
Nies AT; Hofmann U; Resch C; Schaeffeler E; Rius M; Schwab M
PLoS One; 2011; 6(7):e22163. PubMed ID: 21779389
[TBL] [Abstract][Full Text] [Related]
32. Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.
Tahara H; Kusuhara H; Maeda K; Koepsell H; Fuse E; Sugiyama Y
Drug Metab Dispos; 2006 May; 34(5):743-7. PubMed ID: 16455804
[TBL] [Abstract][Full Text] [Related]
33. Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions.
Ahlin G; Chen L; Lazorova L; Chen Y; Ianculescu AG; Davis RL; Giacomini KM; Artursson P
Pharmacogenomics J; 2011 Dec; 11(6):400-11. PubMed ID: 20567254
[TBL] [Abstract][Full Text] [Related]
34. Importance of OCT2 and MATE1 for the Cimetidine-Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition.
Müller F; Weitz D; Mertsch K; König J; Fromm MF
Mol Pharm; 2018 Aug; 15(8):3425-3433. PubMed ID: 29975542
[TBL] [Abstract][Full Text] [Related]
35. Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin.
Wang DS; Jonker JW; Kato Y; Kusuhara H; Schinkel AH; Sugiyama Y
J Pharmacol Exp Ther; 2002 Aug; 302(2):510-5. PubMed ID: 12130709
[TBL] [Abstract][Full Text] [Related]
36. Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.
Meyer zu Schwabedissen HE; Verstuyft C; Kroemer HK; Becquemont L; Kim RB
Am J Physiol Renal Physiol; 2010 Apr; 298(4):F997-F1005. PubMed ID: 20053795
[TBL] [Abstract][Full Text] [Related]
37. Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.
Kimura N; Masuda S; Tanihara Y; Ueo H; Okuda M; Katsura T; Inui K
Drug Metab Pharmacokinet; 2005 Oct; 20(5):379-86. PubMed ID: 16272756
[TBL] [Abstract][Full Text] [Related]
38. Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2.
Suhre WM; Ekins S; Chang C; Swaan PW; Wright SH
Mol Pharmacol; 2005 Apr; 67(4):1067-77. PubMed ID: 15630081
[TBL] [Abstract][Full Text] [Related]
39. Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.
König J; Zolk O; Singer K; Hoffmann C; Fromm MF
Br J Pharmacol; 2011 Jun; 163(3):546-55. PubMed ID: 20883471
[TBL] [Abstract][Full Text] [Related]
40. Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).
Nies AT; Herrmann E; Brom M; Keppler D
Naunyn Schmiedebergs Arch Pharmacol; 2008 Feb; 376(6):449-61. PubMed ID: 18157518
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]