241 related articles for article (PubMed ID: 19251824)
41. Relationship between CYP3A29 and pregnane X receptor in landrace pigs: Pig CYP3A29 has a similar mechanism of regulation to human CYP3A4.
He Y; Zhou X; Li X; Jin X; Wang X; Pan X; Bi D
Comp Biochem Physiol C Toxicol Pharmacol; 2018 Dec; 214():9-16. PubMed ID: 30153482
[TBL] [Abstract][Full Text] [Related]
42. Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells.
Sane RS; Buckley DJ; Buckley AR; Nallani SC; Desai PB
Drug Metab Dispos; 2008 May; 36(5):946-54. PubMed ID: 18299335
[TBL] [Abstract][Full Text] [Related]
43. Establishment of a stable human cell line, HPL-A3, for use in reporter gene assays of cytochrome P450 3A inducers.
Sekimoto M; Sano S; Hosaka T; Nemoto K; Degawa M
Biol Pharm Bull; 2012; 35(5):677-85. PubMed ID: 22687401
[TBL] [Abstract][Full Text] [Related]
44. Effect of panaxytriol on cytochrome P450 3A4 via the pregnane X receptor regulatory pathway.
Wu J; Yao N; Hu Q; Liu M; Zhang H; Xiong Y; Hu J; Xia C
Phytother Res; 2019 Apr; 33(4):968-975. PubMed ID: 30653754
[TBL] [Abstract][Full Text] [Related]
45. Stable overexpression of pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application.
Nibourg GA; Huisman MT; van der Hoeven TV; van Gulik TM; Chamuleau RA; Hoekstra R
Liver Transpl; 2010 Sep; 16(9):1075-85. PubMed ID: 20818746
[TBL] [Abstract][Full Text] [Related]
46. Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor.
DeKeyser JG; Laurenzana EM; Peterson EC; Chen T; Omiecinski CJ
Toxicol Sci; 2011 Apr; 120(2):381-91. PubMed ID: 21227907
[TBL] [Abstract][Full Text] [Related]
47. The alternatively spliced murine pregnane X receptor isoform, mPXR(delta171-211) exhibits a repressive action.
Matic M; Corradin AP; Tsoli M; Clarke SJ; Polly P; Robertson GR
Int J Biochem Cell Biol; 2010 May; 42(5):672-82. PubMed ID: 20060928
[TBL] [Abstract][Full Text] [Related]
48. Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice.
Yamasaki Y; Kobayashi K; Inaba A; Uehara D; Tojima H; Kakizaki S; Chiba K
Xenobiotica; 2018 Nov; 48(11):1098-1105. PubMed ID: 29095659
[TBL] [Abstract][Full Text] [Related]
49. Assessment of Feng-Liao-Chang-Wei-Kang as a potential inducer of cytochrome P450 3A4 and pregnane X receptors.
Xie Y; Li Y; Huang M; Wu Q; Liu Q; Zhang J; Deng H; Liu M; Huang L
Pak J Pharm Sci; 2018 Sep; 31(5(Special)):2315-2321. PubMed ID: 30463833
[TBL] [Abstract][Full Text] [Related]
50. Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.
Fang HL; Strom SC; Ellis E; Duanmu Z; Fu J; Duniec-Dmuchowski Z; Falany CN; Falany JL; Kocarek TA; Runge-Morris M
J Pharmacol Exp Ther; 2007 Nov; 323(2):586-98. PubMed ID: 17687072
[TBL] [Abstract][Full Text] [Related]
51. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha.
Liu FJ; Song X; Yang D; Deng R; Yan B
Biochem J; 2008 Jan; 409(1):243-50. PubMed ID: 17764444
[TBL] [Abstract][Full Text] [Related]
52. In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors.
Zhang W; Purchio A; Chen K; Burns SM; Contag CH; Contag PR
Biochem Pharmacol; 2003 Jun; 65(11):1889-96. PubMed ID: 12781341
[TBL] [Abstract][Full Text] [Related]
53. Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.
Liu YH; Mo SL; Bi HC; Hu BF; Li CG; Wang YT; Huang L; Huang M; Duan W; Liu JP; Wei MQ; Zhou SF
Xenobiotica; 2011 Apr; 41(4):259-80. PubMed ID: 21117944
[TBL] [Abstract][Full Text] [Related]
54. Genome-wide discovery of drug-dependent human liver regulatory elements.
Smith RP; Eckalbar WL; Morrissey KM; Luizon MR; Hoffmann TJ; Sun X; Jones SL; Force Aldred S; Ramamoorthy A; Desta Z; Liu Y; Skaar TC; Trinklein ND; Giacomini KM; Ahituv N
PLoS Genet; 2014 Oct; 10(10):e1004648. PubMed ID: 25275310
[TBL] [Abstract][Full Text] [Related]
55. Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor.
Moscovitz JE; Lin Z; Johnson N; Tu M; Goosen TC; Weng Y; Kalgutkar AS
Xenobiotica; 2018 Jul; 48(7):647-655. PubMed ID: 28685622
[TBL] [Abstract][Full Text] [Related]
56. PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.
Lamba V; Yasuda K; Lamba JK; Assem M; Davila J; Strom S; Schuetz EG
Toxicol Appl Pharmacol; 2004 Sep; 199(3):251-65. PubMed ID: 15364541
[TBL] [Abstract][Full Text] [Related]
57. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
[TBL] [Abstract][Full Text] [Related]
58. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
Lim YP; Kuo SC; Lai ML; Huang JD
Pharmacogenet Genomics; 2009 Jan; 19(1):11-24. PubMed ID: 19077665
[TBL] [Abstract][Full Text] [Related]
59. Intracellular localization of pregnane X receptor in HepG2 cells cultured by the hanging drop method.
Yokobori K; Kobayashi K; Azuma I; Akita H; Chiba K
Drug Metab Pharmacokinet; 2017 Oct; 32(5):265-272. PubMed ID: 28942083
[TBL] [Abstract][Full Text] [Related]
60. Up-regulating CYP3A4 expression in C3A cells by transfection with a novel chimeric regulator of hPXR-p53-AD.
Chen F; Rao XH; Yang JL; Pan MX; Gao Y; Li ZL; Li Y; Zhu YF; Wang Y
PLoS One; 2014; 9(5):e95752. PubMed ID: 24788541
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
