957 related articles for article (PubMed ID: 19252486)
1. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Andriopoulos B; Corradini E; Xia Y; Faasse SA; Chen S; Grgurevic L; Knutson MD; Pietrangelo A; Vukicevic S; Lin HY; Babitt JL
Nat Genet; 2009 Apr; 41(4):482-7. PubMed ID: 19252486
[TBL] [Abstract][Full Text] [Related]
2. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice.
Ramos E; Kautz L; Rodriguez R; Hansen M; Gabayan V; Ginzburg Y; Roth MP; Nemeth E; Ganz T
Hepatology; 2011 Apr; 53(4):1333-41. PubMed ID: 21480335
[TBL] [Abstract][Full Text] [Related]
3. The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
Zhang AS; Gao J; Koeberl DD; Enns CA
J Biol Chem; 2010 May; 285(22):16416-23. PubMed ID: 20363739
[TBL] [Abstract][Full Text] [Related]
4. Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2- and BMP6-mediated signaling and gene expression.
Nili M; Shinde U; Rotwein P
J Biol Chem; 2010 Aug; 285(32):24783-92. PubMed ID: 20530805
[TBL] [Abstract][Full Text] [Related]
5. Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.
Latour C; Besson-Fournier C; Meynard D; Silvestri L; Gourbeyre O; Aguilar-Martinez P; Schmidt PJ; Fleming MD; Roth MP; Coppin H
Hepatology; 2016 Jan; 63(1):126-37. PubMed ID: 26406355
[TBL] [Abstract][Full Text] [Related]
6. Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.
Fillebeen C; Wilkinson N; Charlebois E; Katsarou A; Wagner J; Pantopoulos K
Blood; 2018 Oct; 132(17):1829-1841. PubMed ID: 30213871
[TBL] [Abstract][Full Text] [Related]
7. Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6.
Canali S; Wang CY; Zumbrennen-Bullough KB; Bayer A; Babitt JL
Am J Hematol; 2017 Nov; 92(11):1204-1213. PubMed ID: 28815688
[TBL] [Abstract][Full Text] [Related]
8. Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis.
Corradini E; Garuti C; Montosi G; Ventura P; Andriopoulos B; Lin HY; Pietrangelo A; Babitt JL
Gastroenterology; 2009 Oct; 137(4):1489-97. PubMed ID: 19591830
[TBL] [Abstract][Full Text] [Related]
9. Iron-induced expression of bone morphogenic protein 6 in intestinal cells is the main regulator of hepatic hepcidin expression in vivo.
Arndt S; Maegdefrau U; Dorn C; Schardt K; Hellerbrand C; Bosserhoff AK
Gastroenterology; 2010 Jan; 138(1):372-82. PubMed ID: 19786029
[TBL] [Abstract][Full Text] [Related]
10. Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?
Rausa M; Pagani A; Nai A; Campanella A; Gilberti ME; Apostoli P; Camaschella C; Silvestri L
PLoS One; 2015; 10(4):e0122696. PubMed ID: 25860887
[TBL] [Abstract][Full Text] [Related]
11. Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Canali S; Zumbrennen-Bullough KB; Core AB; Wang CY; Nairz M; Bouley R; Swirski FK; Babitt JL
Blood; 2017 Jan; 129(4):405-414. PubMed ID: 27864295
[TBL] [Abstract][Full Text] [Related]
12. Hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice.
Bartnikas TB; Fleming MD
Haematologica; 2012 Feb; 97(2):189-92. PubMed ID: 21993681
[TBL] [Abstract][Full Text] [Related]
13. Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.
Gkouvatsos K; Wagner J; Papanikolaou G; Sebastiani G; Pantopoulos K
Hepatology; 2011 Nov; 54(5):1800-7. PubMed ID: 21748766
[TBL] [Abstract][Full Text] [Related]
14. Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis.
Lee DH; Zhou LJ; Zhou Z; Xie JX; Jung JU; Liu Y; Xi CX; Mei L; Xiong WC
Blood; 2010 Apr; 115(15):3136-45. PubMed ID: 20065295
[TBL] [Abstract][Full Text] [Related]
15. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.
Babitt JL; Huang FW; Wrighting DM; Xia Y; Sidis Y; Samad TA; Campagna JA; Chung RT; Schneyer AL; Woolf CJ; Andrews NC; Lin HY
Nat Genet; 2006 May; 38(5):531-9. PubMed ID: 16604073
[TBL] [Abstract][Full Text] [Related]
16. Heterozygous Mutations in BMP6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in Humans.
Daher R; Kannengiesser C; Houamel D; Lefebvre T; Bardou-Jacquet E; Ducrot N; de Kerguenec C; Jouanolle AM; Robreau AM; Oudin C; Le Gac G; Moulouel B; Loustaud-Ratti V; Bedossa P; Valla D; Gouya L; Beaumont C; Brissot P; Puy H; Karim Z; Tchernitchko D
Gastroenterology; 2016 Mar; 150(3):672-683.e4. PubMed ID: 26582087
[TBL] [Abstract][Full Text] [Related]
17. Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge.
Latour C; Besson-Fournier C; Gourbeyre O; Meynard D; Roth MP; Coppin H
Blood; 2017 Nov; 130(21):2339-2343. PubMed ID: 29021231
[TBL] [Abstract][Full Text] [Related]
18. Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis.
Silvestri L; Pagani A; Camaschella C
Blood; 2008 Jan; 111(2):924-31. PubMed ID: 17938254
[TBL] [Abstract][Full Text] [Related]
19. BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice.
Corradini E; Schmidt PJ; Meynard D; Garuti C; Montosi G; Chen S; Vukicevic S; Pietrangelo A; Lin HY; Babitt JL
Gastroenterology; 2010 Nov; 139(5):1721-9. PubMed ID: 20682319
[TBL] [Abstract][Full Text] [Related]
20. The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease.
Wang L; Trebicka E; Fu Y; Ellenbogen S; Hong CC; Babitt JL; Lin HY; Cherayil BJ
Inflamm Bowel Dis; 2012 Jan; 18(1):112-9. PubMed ID: 21351217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
