132 related articles for article (PubMed ID: 19256501)
1. Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Wan H; Ahman M; Holmén AG
J Med Chem; 2009 Mar; 52(6):1693-700. PubMed ID: 19256501
[TBL] [Abstract][Full Text] [Related]
2. How well do lipophilicity parameters, MEEKC microemulsion capacity factor, and plasma protein binding predict CNS tissue binding?
Zamek-Gliszczynski MJ; Sprague KE; Espada A; Raub TJ; Morton SM; Manro JR; Molina-Martin M
J Pharm Sci; 2012 May; 101(5):1932-40. PubMed ID: 22344827
[TBL] [Abstract][Full Text] [Related]
3. Microemulsion electrokinetic chromatography hyphenated to atmospheric pressure photoionization mass spectrometry.
Schappler J; Guillarme D; Rudaz S; Veuthey JL
Electrophoresis; 2008 Jan; 29(1):11-9. PubMed ID: 18161697
[TBL] [Abstract][Full Text] [Related]
4. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept.
Reichel A
Chem Biodivers; 2009 Nov; 6(11):2030-49. PubMed ID: 19937839
[TBL] [Abstract][Full Text] [Related]
5. High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Wan H; Rehngren M; Giordanetto F; Bergström F; Tunek A
J Med Chem; 2007 Sep; 50(19):4606-15. PubMed ID: 17725338
[TBL] [Abstract][Full Text] [Related]
6. Predicting blood-brain barrier penetration of drugs by microemulsion liquid chromatography with corrected retention factor.
Liu J; Sun J; Sui X; Wang Y; Hou Y; He Z
J Chromatogr A; 2008 Jul; 1198-1199():164-72. PubMed ID: 18541248
[TBL] [Abstract][Full Text] [Related]
7. High-throughput screening of protein binding by equilibrium dialysis combined with liquid chromatography and mass spectrometry.
Wan H; Rehngren M
J Chromatogr A; 2006 Jan; 1102(1-2):125-34. PubMed ID: 16266710
[TBL] [Abstract][Full Text] [Related]
8. Determination of octanol-water partition coefficients for carbonate esters and other small organic molecules by microemulsion electrokinetic chromatography.
Østergaard J; Hansen SH; Larsen C; Schou C; Heegaard NH
Electrophoresis; 2003 Mar; 24(6):1038-46. PubMed ID: 12658693
[TBL] [Abstract][Full Text] [Related]
9. A quantitative structure-activity approach for lipophilicity estimation of antitumor complexes of different metals using microemulsion electrokinetic chromatography.
Foteeva LS; Trofimov DA; Kuznetsova OV; Kowol CR; Arion VB; Keppler BK; Timerbaev AR
J Pharm Biomed Anal; 2011 Jun; 55(3):409-13. PubMed ID: 21382684
[TBL] [Abstract][Full Text] [Related]
10. Anion-selective exhaustive injection-sweeping microemulsion electrokinetic chromatography.
Huang HY; Lien WC; Huang IY
Electrophoresis; 2006 Aug; 27(16):3202-9. PubMed ID: 16850505
[TBL] [Abstract][Full Text] [Related]
11. Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice.
Maurer TS; Debartolo DB; Tess DA; Scott DO
Drug Metab Dispos; 2005 Jan; 33(1):175-81. PubMed ID: 15502010
[TBL] [Abstract][Full Text] [Related]
12. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics.
Shen DD; Artru AA; Adkison KK
Adv Drug Deliv Rev; 2004 Oct; 56(12):1825-57. PubMed ID: 15381336
[TBL] [Abstract][Full Text] [Related]
13. Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Longhi R; Corbioli S; Fontana S; Vinco F; Braggio S; Helmdach L; Schiller J; Boriss H
Drug Metab Dispos; 2011 Feb; 39(2):312-21. PubMed ID: 21071520
[TBL] [Abstract][Full Text] [Related]
14. Improvement of microemulsion electrokinetic chromatography for measuring octanol-water partition coefficients.
Xia Z; Jiang X; Mu X; Chen H
Electrophoresis; 2008 Feb; 29(4):835-42. PubMed ID: 18203250
[TBL] [Abstract][Full Text] [Related]
15. High throughput screening of physicochemical properties and in vitro ADME profiling in drug discovery.
Wan H; Holmén AG
Comb Chem High Throughput Screen; 2009 Mar; 12(3):315-29. PubMed ID: 19275537
[TBL] [Abstract][Full Text] [Related]
16. Assessing brain free fraction in early drug discovery.
Read KD; Braggio S
Expert Opin Drug Metab Toxicol; 2010 Mar; 6(3):337-44. PubMed ID: 20102287
[TBL] [Abstract][Full Text] [Related]
17. PK/PD assessment in CNS drug discovery: Prediction of CSF concentration in rodents for P-glycoprotein substrates and application to in vivo potency estimation.
Caruso A; Alvarez-Sánchez R; Hillebrecht A; Poirier A; Schuler F; Lavé T; Funk C; Belli S
Biochem Pharmacol; 2013 Jun; 85(11):1684-99. PubMed ID: 23454189
[TBL] [Abstract][Full Text] [Related]
18. Recent applications of microemulsion electrokinetic chromatography.
Huie CW
Electrophoresis; 2006 Jan; 27(1):60-75. PubMed ID: 16315183
[TBL] [Abstract][Full Text] [Related]
19. Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction.
Summerfield SG; Read K; Begley DJ; Obradovic T; Hidalgo IJ; Coggon S; Lewis AV; Porter RA; Jeffrey P
J Pharmacol Exp Ther; 2007 Jul; 322(1):205-13. PubMed ID: 17405866
[TBL] [Abstract][Full Text] [Related]
20. Potential of biopartitioning micellar chromatography as an in vitro technique for predicting drug penetration across the blood-brain barrier.
Escuder-Gilabert L; Molero-Monfort M; Villanueva-Camañas RM; Sagrado S; Medina-Hernández MJ
J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Aug; 807(2):193-201. PubMed ID: 15203029
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
