BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 19260824)

  • 1. Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity.
    Riedle S; Kiefel H; Gast D; Bondong S; Wolterink S; Gutwein P; Altevogt P
    Biochem J; 2009 May; 420(3):391-402. PubMed ID: 19260824
    [TBL] [Abstract][Full Text] [Related]  

  • 2. L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth.
    Maretzky T; Schulte M; Ludwig A; Rose-John S; Blobel C; Hartmann D; Altevogt P; Saftig P; Reiss K
    Mol Cell Biol; 2005 Oct; 25(20):9040-53. PubMed ID: 16199880
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
    Tousseyn T; Thathiah A; Jorissen E; Raemaekers T; Konietzko U; Reiss K; Maes E; Snellinx A; Serneels L; Nyabi O; Annaert W; Saftig P; Hartmann D; De Strooper B
    J Biol Chem; 2009 Apr; 284(17):11738-47. PubMed ID: 19213735
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.
    Doberstein K; Pfeilschifter J; Gutwein P
    Carcinogenesis; 2011 Nov; 32(11):1713-23. PubMed ID: 21880579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).
    Houri N; Huang KC; Nalbantoglu J
    PLoS One; 2013; 8(8):e73296. PubMed ID: 24015300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ADAM10 is upregulated in melanoma metastasis compared with primary melanoma.
    Lee SB; Schramme A; Doberstein K; Dummer R; Abdel-Bakky MS; Keller S; Altevogt P; Oh ST; Reichrath J; Oxmann D; Pfeilschifter J; Mihic-Probst D; Gutwein P
    J Invest Dermatol; 2010 Mar; 130(3):763-73. PubMed ID: 19865098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
    Stoeck A; Shang L; Dempsey PJ
    J Cell Sci; 2010 Jul; 123(Pt 13):2319-31. PubMed ID: 20530572
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
    Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
    J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Presenilin/gamma-secretase-mediated cleavage regulates association of leukocyte-common antigen-related (LAR) receptor tyrosine phosphatase with beta-catenin.
    Haapasalo A; Kim DY; Carey BW; Turunen MK; Pettingell WH; Kovacs DM
    J Biol Chem; 2007 Mar; 282(12):9063-72. PubMed ID: 17259169
    [TBL] [Abstract][Full Text] [Related]  

  • 10. L1 stimulation of human glioma cell motility correlates with FAK activation.
    Yang M; Li Y; Chilukuri K; Brady OA; Boulos MI; Kappes JC; Galileo DS
    J Neurooncol; 2011 Oct; 105(1):27-44. PubMed ID: 21373966
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein.
    Seipold L; Damme M; Prox J; Rabe B; Kasparek P; Sedlacek R; Altmeppen H; Willem M; Boland B; Glatzel M; Saftig P
    Biochim Biophys Acta Mol Cell Res; 2017 Jan; 1864(1):217-230. PubMed ID: 27818272
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.
    Tippmann F; Hundt J; Schneider A; Endres K; Fahrenholz F
    FASEB J; 2009 Jun; 23(6):1643-54. PubMed ID: 19144697
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.
    LaVoie MJ; Selkoe DJ
    J Biol Chem; 2003 Sep; 278(36):34427-37. PubMed ID: 12826675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer.
    Arima T; Enokida H; Kubo H; Kagara I; Matsuda R; Toki K; Nishimura H; Chiyomaru T; Tatarano S; Idesako T; Nishiyama K; Nakagawa M
    Cancer Sci; 2007 Nov; 98(11):1720-6. PubMed ID: 17727679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44.
    Stoeck A; Keller S; Riedle S; Sanderson MP; Runz S; Le Naour F; Gutwein P; Ludwig A; Rubinstein E; Altevogt P
    Biochem J; 2006 Feb; 393(Pt 3):609-18. PubMed ID: 16229685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.
    Gavert N; Sheffer M; Raveh S; Spaderna S; Shtutman M; Brabletz T; Barany F; Paty P; Notterman D; Domany E; Ben-Ze'ev A
    Cancer Res; 2007 Aug; 67(16):7703-12. PubMed ID: 17699774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.
    Schulz B; Pruessmeyer J; Maretzky T; Ludwig A; Blobel CP; Saftig P; Reiss K
    Circ Res; 2008 May; 102(10):1192-201. PubMed ID: 18420943
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.
    Berezovska O; Jack C; McLean P; Aster JC; Hicks C; Xia W; Wolfe MS; Kimberly WT; Weinmaster G; Selkoe DJ; Hyman BT
    J Neurochem; 2000 Aug; 75(2):583-93. PubMed ID: 10899933
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10.
    Prox J; Willenbrock M; Weber S; Lehmann T; Schmidt-Arras D; Schwanbeck R; Saftig P; Schwake M
    Cell Mol Life Sci; 2012 Sep; 69(17):2919-32. PubMed ID: 22446748
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MicroRNA-144 is regulated by activator protein-1 (AP-1) and decreases expression of Alzheimer disease-related a disintegrin and metalloprotease 10 (ADAM10).
    Cheng C; Li W; Zhang Z; Yoshimura S; Hao Q; Zhang C; Wang Z
    J Biol Chem; 2013 May; 288(19):13748-61. PubMed ID: 23546882
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.