These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 19261750)

  • 1. Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.
    Cui B; Johnson SP; Bullock N; Ali-Osman F; Bigner DD; Friedman HS
    Mol Pharmacol; 2009 Jun; 75(6):1356-63. PubMed ID: 19261750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATR-Chk1 activation mitigates replication stress caused by mismatch repair-dependent processing of DNA damage.
    Gupta D; Lin B; Cowan A; Heinen CD
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1523-1528. PubMed ID: 29378956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.
    Stojic L; Mojas N; Cejka P; Di Pietro M; Ferrari S; Marra G; Jiricny J
    Genes Dev; 2004 Jun; 18(11):1331-44. PubMed ID: 15175264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways.
    Pichierri P; Rosselli F
    EMBO J; 2004 Mar; 23(5):1178-87. PubMed ID: 14988723
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.
    Koppenhafer SL; Goss KL; Terry WW; Gordon DJ
    Mol Cancer Res; 2020 Jan; 18(1):91-104. PubMed ID: 31649026
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts.
    Bélanger F; Rajotte V; Drobetsky EA
    PLoS One; 2014; 9(1):e85294. PubMed ID: 24416382
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus.
    Luciani MG; Oehlmann M; Blow JJ
    J Cell Sci; 2004 Dec; 117(Pt 25):6019-30. PubMed ID: 15536124
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase.
    Buisson R; Boisvert JL; Benes CH; Zou L
    Mol Cell; 2015 Sep; 59(6):1011-24. PubMed ID: 26365377
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical role of SMG7 in activation of the ATR-CHK1 axis in response to genotoxic stress.
    Ho K; Luo H; Zhu W; Tang Y
    Sci Rep; 2021 Apr; 11(1):7502. PubMed ID: 33820915
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.
    Guo Y; Wang J; Benedict B; Yang C; van Gemert F; Ma X; Gao D; Wang H; Zhang S; Lieftink C; Beijersbergen RL; Te Riele H; Qiao X; Gao Q; Sun C; Qin W; Bernards R; Wang C
    Genome Med; 2021 Oct; 13(1):166. PubMed ID: 34663432
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G
    Mladenov E; Fan X; Paul-Konietzko K; Soni A; Iliakis G
    Sci Rep; 2019 Oct; 9(1):14597. PubMed ID: 31601897
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
    Fang Y; Tsao CC; Goodman BK; Furumai R; Tirado CA; Abraham RT; Wang XF
    EMBO J; 2004 Aug; 23(15):3164-74. PubMed ID: 15282542
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase inhibition is synthetically lethal in XRCC1 deficient ovarian cancer cells.
    Sultana R; Abdel-Fatah T; Perry C; Moseley P; Albarakti N; Mohan V; Seedhouse C; Chan S; Madhusudan S
    PLoS One; 2013; 8(2):e57098. PubMed ID: 23451157
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New horizons in lung cancer management through ATR/CHK1 pathway modulation.
    Thapa R; Afzal O; Bhat AA; Goyal A; Alfawaz Altamimi AS; Almalki WH; Alzarea SI; Kazmi I; Singh SK; Dua K; Thangavelu L; Gupta G
    Future Med Chem; 2023 Oct; 15(19):1807-1818. PubMed ID: 37877252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors.
    Qiu Z; Fa P; Liu T; Prasad CB; Ma S; Hong Z; Chan ER; Wang H; Li Z; He K; Wang QE; Williams TM; Yan C; Sizemore ST; Narla G; Zhang J
    Cancer Res; 2020 Aug; 80(16):3305-3318. PubMed ID: 32522823
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy.
    Manic G; Obrist F; Sistigu A; Vitale I
    Mol Cell Oncol; 2015; 2(4):e1012976. PubMed ID: 27308506
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint.
    Jiang Z; Jin S; Yalowich JC; Brown KD; Rajasekaran B
    Mol Cancer Ther; 2010 Mar; 9(3):558-68. PubMed ID: 20145018
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monitoring Chk1 kinase activity dynamics in live single cell imaging assays.
    Lebrec V; Gavet O
    Methods Cell Biol; 2024; 182():221-236. PubMed ID: 38359979
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bloom syndrome DNA helicase mitigates mismatch repair-dependent apoptosis.
    Uechi Y; Fujikane R; Morita S; Tamaoki S; Hidaka M
    Biochem Biophys Res Commun; 2024 Sep; 723():150214. PubMed ID: 38850810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.
    Kato N; Kawasoe Y; Williams H; Coates E; Roy U; Shi Y; Beese LS; Schärer OD; Yan H; Gottesman ME; Takahashi TS; Gautier J
    Cell Rep; 2017 Oct; 21(5):1375-1385. PubMed ID: 29091773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.