BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

833 related articles for article (PubMed ID: 19263472)

  • 1. Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.
    Murata M; Matsuzaki K; Yoshida K; Sekimoto G; Tahashi Y; Mori S; Uemura Y; Sakaida N; Fujisawa J; Seki T; Kobayashi K; Yokote K; Koike K; Okazaki K
    Hepatology; 2009 Apr; 49(4):1203-17. PubMed ID: 19263472
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
    Matsuzaki K; Murata M; Yoshida K; Sekimoto G; Uemura Y; Sakaida N; Kaibori M; Kamiyama Y; Nishizawa M; Fujisawa J; Okazaki K; Seki T
    Hepatology; 2007 Jul; 46(1):48-57. PubMed ID: 17596875
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21(WAF1) pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells.
    Li Q; Liu G; Yuan H; Wang J; Guo Y; Chen T; Zhai R; Shao D; Ni W; Tai G
    Oncotarget; 2015 Feb; 6(6):4253-65. PubMed ID: 25714018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. c-Jun N-terminal kinase inhibitor favors transforming growth factor-β to antagonize hepatitis B virus X protein-induced cell growth promotion in hepatocellular carcinoma.
    Wu YH; Ai X; Liu FY; Liang HF; Zhang BX; Chen XP
    Mol Med Rep; 2016 Feb; 13(2):1345-52. PubMed ID: 26648552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis.
    Kawamata S; Matsuzaki K; Murata M; Seki T; Matsuoka K; Iwao Y; Hibi T; Okazaki K
    Inflamm Bowel Dis; 2011 Mar; 17(3):683-95. PubMed ID: 20602465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma.
    Nagata H; Hatano E; Tada M; Murata M; Kitamura K; Asechi H; Narita M; Yanagida A; Tamaki N; Yagi S; Ikai I; Matsuzaki K; Uemoto S
    Hepatology; 2009 Jun; 49(6):1944-53. PubMed ID: 19418558
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Linker phosphorylation of Smad3 promotes fibro-carcinogenesis in chronic viral hepatitis of hepatocellular carcinoma.
    Murata M; Yoshida K; Yamaguchi T; Matsuzaki K
    World J Gastroenterol; 2014 Nov; 20(41):15018-27. PubMed ID: 25386050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis.
    Matsuzaki K
    Histol Histopathol; 2006 Jun; 21(6):645-62. PubMed ID: 16528675
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.
    Deng YR; Yoshida K; Jin QL; Murata M; Yamaguchi T; Tsuneyama K; Moritoki Y; Niu JQ; Matsuzaki K; Lian ZX
    Clin Exp Immunol; 2014 Apr; 176(1):102-11. PubMed ID: 24372395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smad Phospho-Isoforms for Hepatocellular Carcinoma Risk Assessment in Patients with Nonalcoholic Steatohepatitis.
    Suwa K; Yamaguchi T; Yoshida K; Murata M; Ichimura M; Tsuneyama K; Seki T; Okazaki K
    Cancers (Basel); 2020 Jan; 12(2):. PubMed ID: 31991602
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.
    Yamagata H; Matsuzaki K; Mori S; Yoshida K; Tahashi Y; Furukawa F; Sekimoto G; Watanabe T; Uemura Y; Sakaida N; Yoshioka K; Kamiyama Y; Seki T; Okazaki K
    Cancer Res; 2005 Jan; 65(1):157-65. PubMed ID: 15665291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy.
    Kim SH; Ahn S; Park CK
    Hepatobiliary Pancreat Dis Int; 2012 Feb; 11(1):51-9. PubMed ID: 22251470
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling.
    Liu R; Tang C; Shen A; Luo H; Wei X; Zheng D; Sun C; Li Z; Zhu D; Li T; Wu Z
    Oncotarget; 2016 Dec; 7(51):85079-85096. PubMed ID: 27835881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TGF-beta during human colorectal carcinogenesis: the shift from epithelial to mesenchymal signaling.
    Matsuzaki K; Seki T; Okazaki K
    Inflammopharmacology; 2006 Dec; 14(5-6):198-203. PubMed ID: 17093904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Large hepatitis delta antigen modulates transforming growth factor-beta signaling cascades: implication of hepatitis delta virus-induced liver fibrosis.
    Choi SH; Jeong SH; Hwang SB
    Gastroenterology; 2007 Jan; 132(1):343-57. PubMed ID: 17241884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatitis B virus X induces cell proliferation in the hepatocarcinogenesis via up-regulation of cytoplasmic p21 expression.
    Yano M; Ohkoshi S; Aoki YH; Takahashi H; Kurita S; Yamazaki K; Suzuki K; Yamagiwa S; Sanpei A; Fujimaki S; Wakai T; Kudo SE; Matsuda Y; Aoyagi Y
    Liver Int; 2013 Sep; 33(8):1218-29. PubMed ID: 23590292
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the
    Hama T; Nakanishi K; Sato M; Mukaiyama H; Togawa H; Shima Y; Miyajima M; Nozu K; Nagao S; Takahashi H; Sako M; Iijima K; Yoshikawa N; Suzuki H
    Am J Physiol Renal Physiol; 2017 Dec; 313(6):F1223-F1231. PubMed ID: 28877884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Integration of the hepatitis B virus X fragment in hepatocellular carcinoma and its effects on the expression of multiple molecules: a key to the cell cycle and apoptosis.
    Peng Z; Zhang Y; Gu W; Wang Z; Li D; Zhang F; Qiu G; Xie K
    Int J Oncol; 2005 Feb; 26(2):467-73. PubMed ID: 15645132
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatitis C viral proteins interact with Smad3 and differentially regulate TGF-beta/Smad3-mediated transcriptional activation.
    Cheng PL; Chang MH; Chao CH; Lee YH
    Oncogene; 2004 Oct; 23(47):7821-38. PubMed ID: 15334054
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.