BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

859 related articles for article (PubMed ID: 19267423)

  • 1. Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.
    Wang PL; Niidome T; Akaike A; Kihara T; Sugimoto H
    J Neurosci Res; 2009 Jul; 87(9):2105-14. PubMed ID: 19267423
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rac1 changes the substrate specificity of gamma-secretase between amyloid precursor protein and Notch1.
    Boo JH; Sohn JH; Kim JE; Song H; Mook-Jung I
    Biochem Biophys Res Commun; 2008 Aug; 372(4):913-7. PubMed ID: 18538664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA.
    Luo HM; Deng H; Xiao F; Gao Q; Weng W; Zhang PF; Li XG
    Acta Pharmacol Sin; 2004 Dec; 25(12):1613-8. PubMed ID: 15569405
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J; Ray WJ; Espeseth A; Simon A; Shi XP; Wolffe C; Getty K; Marine S; Stec E; Ferrer M; Strulovici B; Bartz S; Gates A; Xu M; Huang Q; Ma L; Shughrue P; Burchard J; Colussi D; Pietrak B; Kahana J; Beher D; Rosahl T; Shearman M; Hazuda D; Sachs AB; Koblan KS; Seabrook GR; Stone DJ
    Proc Natl Acad Sci U S A; 2006 Nov; 103(47):17967-72. PubMed ID: 17098871
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
    Mohmmad Abdul H; Sultana R; Keller JN; St Clair DK; Markesbery WR; Butterfield DA
    J Neurochem; 2006 Mar; 96(5):1322-35. PubMed ID: 16478525
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of amyloid precursor protein is associated with degeneration, decreased viability, and increased damage caused by neurotoxins (prostaglandins A1 and E2, hydrogen peroxide, and nitric oxide) in differentiated neuroblastoma cells.
    Hanson AJ; Prasad JE; Nahreini P; Andreatta C; Kumar B; Yan XD; Prasad KN
    J Neurosci Res; 2003 Oct; 74(1):148-59. PubMed ID: 13130517
    [TBL] [Abstract][Full Text] [Related]  

  • 7. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
    Lin HC; Hsieh HM; Chen YH; Hu ML
    Neurotoxicology; 2009 Jul; 30(4):622-7. PubMed ID: 19635394
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells.
    Schmidt C; Lepsverdize E; Chi SL; Das AM; Pizzo SV; Dityatev A; Schachner M
    Mol Psychiatry; 2008 Oct; 13(10):953-69. PubMed ID: 17726461
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region.
    Ge YW; Ghosh C; Song W; Maloney B; Lahiri DK
    J Neurochem; 2004 Sep; 90(6):1432-44. PubMed ID: 15341527
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
    J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH
    J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Abeta production by NF-kappaB inhibitors.
    Paris D; Patel N; Quadros A; Linan M; Bakshi P; Ait-Ghezala G; Mullan M
    Neurosci Lett; 2007 Mar; 415(1):11-6. PubMed ID: 17223266
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40.
    van Dijk R; Fischer DF; Sluijs JA; Sonnemans MA; Hobo B; Mercken L; Mann DM; Hol EM; van Leeuwen FW
    J Neurochem; 2004 Aug; 90(3):712-23. PubMed ID: 15255950
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
    J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Rac1 GTPase downregulates vascular endothelial growth factor receptor-2 expression by suppressing Sp1-dependent DNA binding in human endothelial cells.
    Meissner M; Michailidou D; Stein M; Hrgovic I; Kaufmann R; Gille J
    Exp Dermatol; 2009 Oct; 18(10):863-9. PubMed ID: 19469899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amyloid-beta precursor protein mediates neuronal toxicity of amyloid beta through Go protein activation.
    Sola Vigo F; Kedikian G; Heredia L; Heredia F; Añel AD; Rosa AL; Lorenzo A
    Neurobiol Aging; 2009 Sep; 30(9):1379-92. PubMed ID: 18187234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and Abeta production in cortical neurons.
    Gavín R; Ureña J; Rangel A; Pastrana MA; Requena JR; Soriano E; Aguzzi A; Del Río JA
    Neurobiol Dis; 2008 May; 30(2):243-54. PubMed ID: 18374587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?
    Nawrot B
    Acta Biochim Pol; 2004; 51(2):431-44. PubMed ID: 15218540
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TAG-1 is an inhibitor of TGFbeta2-induced neuronal death via amyloid beta precursor protein.
    Tachi N; Hashimoto Y; Nawa M; Matsuoka M
    Biochem Biophys Res Commun; 2010 Mar; 394(1):119-25. PubMed ID: 20184861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site.
    Flood F; Murphy S; Cowburn RF; Lannfelt L; Walker B; Johnston JA
    Biochem J; 2005 Jan; 385(Pt 2):545-50. PubMed ID: 15473868
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 43.