257 related articles for article (PubMed ID: 19269046)
1. The apparent cooperativity of some GPCRs does not necessarily imply dimerization.
Chabre M; Deterre P; Antonny B
Trends Pharmacol Sci; 2009 Apr; 30(4):182-7. PubMed ID: 19269046
[TBL] [Abstract][Full Text] [Related]
2. Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding.
Albizu L; Balestre MN; Breton C; Pin JP; Manning M; Mouillac B; Barberis C; Durroux T
Mol Pharmacol; 2006 Nov; 70(5):1783-91. PubMed ID: 16926282
[TBL] [Abstract][Full Text] [Related]
3. Ligand screening system using fusion proteins of G protein-coupled receptors with G protein alpha subunits.
Suga H; Haga T
Neurochem Int; 2007; 51(2-4):140-64. PubMed ID: 17659814
[TBL] [Abstract][Full Text] [Related]
4. Negative cooperativity in H2 relaxin binding to a dimeric relaxin family peptide receptor 1.
Svendsen AM; Zalesko A; Kønig J; Vrecl M; Heding A; Kristensen JB; Wade JD; Bathgate RA; De Meyts P; Nøhr J
Mol Cell Endocrinol; 2008 Dec; 296(1-2):10-7. PubMed ID: 18723073
[TBL] [Abstract][Full Text] [Related]
5. Allosteric properties of G protein-coupled receptor oligomers.
Springael JY; Urizar E; Costagliola S; Vassart G; Parmentier M
Pharmacol Ther; 2007 Sep; 115(3):410-8. PubMed ID: 17655934
[TBL] [Abstract][Full Text] [Related]
6. Dimerization and oligomerization of G-protein-coupled receptors: debated structures with established and emerging functions.
Szidonya L; Cserzo M; Hunyady L
J Endocrinol; 2008 Mar; 196(3):435-53. PubMed ID: 18310440
[TBL] [Abstract][Full Text] [Related]
7. Orphan GPCRs and their ligands.
Civelli O; Saito Y; Wang Z; Nothacker HP; Reinscheid RK
Pharmacol Ther; 2006 Jun; 110(3):525-32. PubMed ID: 16289308
[TBL] [Abstract][Full Text] [Related]
8. Understanding the ligand-receptor-G protein ternary complex for GPCR drug discovery.
Ratnala VR; Kobilka B
Methods Mol Biol; 2009; 552():67-77. PubMed ID: 19513642
[TBL] [Abstract][Full Text] [Related]
9. G-protein-coupled receptors: from classical modes of modulation to allosteric mechanisms.
Bridges TM; Lindsley CW
ACS Chem Biol; 2008 Sep; 3(9):530-41. PubMed ID: 18652471
[TBL] [Abstract][Full Text] [Related]
10. The ligand-independent translocation assay: an enabling technology for screening orphan G protein-coupled receptors by arrestin recruitment.
Oakley RH; Hudson CC; Sjaastad MD; Loomis CR
Methods Enzymol; 2006; 414():50-63. PubMed ID: 17110186
[TBL] [Abstract][Full Text] [Related]
11. Dimerization and negative cooperativity in the relaxin family peptide receptors.
Svendsen AM; Vrecl M; Knudsen L; Heding A; Wade JD; Bathgate RA; De Meyts P; Nøhr J
Ann N Y Acad Sci; 2009 Apr; 1160():54-9. PubMed ID: 19416159
[TBL] [Abstract][Full Text] [Related]
12. Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs.
Valant C; Sexton PM; Christopoulos A
Mol Interv; 2009 Jun; 9(3):125-35. PubMed ID: 19592673
[TBL] [Abstract][Full Text] [Related]
13. Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains.
Agnati LF; Leo G; Genedani S; Andreoli N; Marcellino D; Woods A; Piron L; Guidolin D; Fuxe K
Brain Res Rev; 2008 Aug; 58(2):459-74. PubMed ID: 18022243
[TBL] [Abstract][Full Text] [Related]
14. Principles: a model for the allosteric interactions between ligand binding sites within a dimeric GPCR.
Durroux T
Trends Pharmacol Sci; 2005 Jul; 26(7):376-84. PubMed ID: 15946747
[TBL] [Abstract][Full Text] [Related]
15. Asymmetric conformational changes in a GPCR dimer controlled by G-proteins.
Damian M; Martin A; Mesnier D; Pin JP; Banères JL
EMBO J; 2006 Dec; 25(24):5693-702. PubMed ID: 17139258
[TBL] [Abstract][Full Text] [Related]
16. The use of constitutively active receptors for drug discovery at the G protein-coupled receptor gene pool.
Behan DP; Chalmers DT
Curr Opin Drug Discov Devel; 2001 Sep; 4(5):548-60. PubMed ID: 12825451
[TBL] [Abstract][Full Text] [Related]
17. Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
Parthier C; Reedtz-Runge S; Rudolph R; Stubbs MT
Trends Biochem Sci; 2009 Jun; 34(6):303-10. PubMed ID: 19446460
[TBL] [Abstract][Full Text] [Related]
18. Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors.
Wheatley M; Simms J; Hawtin SR; Wesley VJ; Wootten D; Conner M; Lawson Z; Conner AC; Baker A; Cashmore Y; Kendrick R; Parslow RA
Biochem Soc Trans; 2007 Aug; 35(Pt 4):717-20. PubMed ID: 17635132
[TBL] [Abstract][Full Text] [Related]
19. G protein-coupled receptor dimers: functional consequences, disease states and drug targets.
Dalrymple MB; Pfleger KD; Eidne KA
Pharmacol Ther; 2008 Jun; 118(3):359-71. PubMed ID: 18486226
[TBL] [Abstract][Full Text] [Related]
20. Signaling mechanisms of GPCR ligands.
Strange PG
Curr Opin Drug Discov Devel; 2008 Mar; 11(2):196-202. PubMed ID: 18283607
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]