739 related articles for article (PubMed ID: 19269068)
1. Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors.
Park H; Bhattarai BR; Ham SW; Cho H
Eur J Med Chem; 2009 Aug; 44(8):3280-4. PubMed ID: 19269068
[TBL] [Abstract][Full Text] [Related]
2. Discovery of novel alpha-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure.
Park H; Hwang KY; Oh KH; Kim YH; Lee JY; Kim K
Bioorg Med Chem; 2008 Jan; 16(1):284-92. PubMed ID: 17920282
[TBL] [Abstract][Full Text] [Related]
3. Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitors.
Park H; Li M; Choi J; Cho H; Ham SW
Bioorg Med Chem Lett; 2009 Aug; 19(15):4372-5. PubMed ID: 19500977
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening.
Park H; Jung SK; Jeong DG; Ryu SE; Kim SJ
Bioorg Med Chem Lett; 2008 Apr; 18(7):2250-5. PubMed ID: 18358718
[TBL] [Abstract][Full Text] [Related]
5. Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening.
Park H; Bahn YJ; Jung SK; Jeong DG; Lee SH; Seo I; Yoon TS; Kim SJ; Ryu SE
J Med Chem; 2008 Sep; 51(18):5533-41. PubMed ID: 18714978
[TBL] [Abstract][Full Text] [Related]
6. Studies of the mechanism of selectivity of protein tyrosine phosphatase 1B (PTP1B) bidentate inhibitors using molecular dynamics simulations and free energy calculations.
Fang L; Zhang H; Cui W; Ji M
J Chem Inf Model; 2008 Oct; 48(10):2030-41. PubMed ID: 18831546
[TBL] [Abstract][Full Text] [Related]
7. Identification of novel inhibitors of extracellular signal-regulated kinase 2 based on the structure-based virtual screening.
Park H; Bahn YJ; Jeong DG; Woo EJ; Kwon JS; Ryu SE
Bioorg Med Chem Lett; 2008 Oct; 18(20):5372-6. PubMed ID: 18835158
[TBL] [Abstract][Full Text] [Related]
8. Discovery and biological evaluation of novel alpha-glucosidase inhibitors with in vivo antidiabetic effect.
Park H; Hwang KY; Kim YH; Oh KH; Lee JY; Kim K
Bioorg Med Chem Lett; 2008 Jul; 18(13):3711-5. PubMed ID: 18524587
[TBL] [Abstract][Full Text] [Related]
9. Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening.
Cosconati S; Marinelli L; La Motta C; Sartini S; Da Settimo F; Olson AJ; Novellino E
J Med Chem; 2009 Sep; 52(18):5578-81. PubMed ID: 19719141
[TBL] [Abstract][Full Text] [Related]
10. Probing interaction requirements in PTP1B inhibitors: a comparative molecular dynamics study.
Kumar R; Shinde RN; Ajay D; Sobhia ME
J Chem Inf Model; 2010 Jun; 50(6):1147-58. PubMed ID: 20455572
[TBL] [Abstract][Full Text] [Related]
11. Molecular dynamics studies on the interactions of PTP1B with inhibitors: from the first phosphate-binding site to the second one.
Wang JF; Gong K; Wei DQ; Li YX; Chou KC
Protein Eng Des Sel; 2009 Jun; 22(6):349-55. PubMed ID: 19380334
[TBL] [Abstract][Full Text] [Related]
12. Interpretation of the binding affinities of PTP1B inhibitors with the MM-GB/SA method and the X-score scoring function.
Zhang X; Li X; Wang R
J Chem Inf Model; 2009 Apr; 49(4):1033-48. PubMed ID: 19320460
[TBL] [Abstract][Full Text] [Related]
13. Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.
Maccari R; Ottanà R; Ciurleo R; Paoli P; Manao G; Camici G; Laggner C; Langer T
ChemMedChem; 2009 Jun; 4(6):957-62. PubMed ID: 19288492
[TBL] [Abstract][Full Text] [Related]
14. Structure-based virtual screening approach to the discovery of novel inhibitors of factor-inhibiting HIF-1: identification of new chelating groups for the active-site ferrous ion.
Ko S; Lee MK; Shin D; Park H
Bioorg Med Chem; 2009 Nov; 17(22):7769-74. PubMed ID: 19822432
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
Qiu WW; Shen Q; Yang F; Wang B; Zou H; Li JY; Li J; Tang J
Bioorg Med Chem Lett; 2009 Dec; 19(23):6618-22. PubMed ID: 19846303
[TBL] [Abstract][Full Text] [Related]
16. Rationalizing protein-ligand interactions for PTP1B inhibitors using computational methods.
Ajmani S; Karanam S; Kulkarni SA
Chem Biol Drug Des; 2009 Dec; 74(6):582-95. PubMed ID: 19824894
[TBL] [Abstract][Full Text] [Related]
17. Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.
Szczepankiewicz BG; Liu G; Hajduk PJ; Abad-Zapatero C; Pei Z; Xin Z; Lubben TH; Trevillyan JM; Stashko MA; Ballaron SJ; Liang H; Huang F; Hutchins CW; Fesik SW; Jirousek MR
J Am Chem Soc; 2003 Apr; 125(14):4087-96. PubMed ID: 12670229
[TBL] [Abstract][Full Text] [Related]
18. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
Zhang S; Zhang ZY
Drug Discov Today; 2007 May; 12(9-10):373-81. PubMed ID: 17467573
[TBL] [Abstract][Full Text] [Related]
19. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
Rao GS; Ramachandran MV; Bajaj JS
J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
[TBL] [Abstract][Full Text] [Related]
20. Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy.
Chen X; Gan Q; Feng C; Liu X; Zhang Q
J Chem Inf Model; 2018 Apr; 58(4):837-847. PubMed ID: 29608303
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
