BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 19272020)

  • 1. Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function.
    Dove SK; Dong K; Kobayashi T; Williams FK; Michell RH
    Biochem J; 2009 Apr; 419(1):1-13. PubMed ID: 19272020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphatidylinositol 3,5-Bisphosphate-Rich Membrane Domains in Endosomes and Lysosomes.
    Takatori S; Tatematsu T; Cheng J; Matsumoto J; Akano T; Fujimoto T
    Traffic; 2016 Feb; 17(2):154-67. PubMed ID: 26563567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions.
    Michell RH; Heath VL; Lemmon MA; Dove SK
    Trends Biochem Sci; 2006 Jan; 31(1):52-63. PubMed ID: 16364647
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors.
    Dove SK; Piper RC; McEwen RK; Yu JW; King MC; Hughes DC; Thuring J; Holmes AB; Cooke FT; Michell RH; Parker PJ; Lemmon MA
    EMBO J; 2004 May; 23(9):1922-33. PubMed ID: 15103325
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
    Sbrissa D; Ikonomov OC; Fu Z; Ijuin T; Gruenberg J; Takenawa T; Shisheva A
    J Biol Chem; 2007 Aug; 282(33):23878-91. PubMed ID: 17556371
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate.
    Yordanov TE; Hipolito VEB; Liebscher G; Vogel GF; Stasyk T; Herrmann C; Geley S; Teis D; Botelho RJ; Hess MW; Huber LA
    Traffic; 2019 Sep; 20(9):674-696. PubMed ID: 31314175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.
    Saffi GT; Wang CA; Mangialardi EM; Vacher J; Botelho RJ; Salmena L
    J Biol Chem; 2022 Aug; 298(8):102187. PubMed ID: 35760104
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PtdIns(3,5)P2 finds a partner.
    Hicke L
    Dev Cell; 2003 Sep; 5(3):363-4. PubMed ID: 12967555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.
    Ho CY; Choy CH; Wattson CA; Johnson DE; Botelho RJ
    J Biol Chem; 2015 Apr; 290(15):9919-28. PubMed ID: 25713145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate.
    Efe JA; Botelho RJ; Emr SD
    Mol Biol Cell; 2007 Nov; 18(11):4232-44. PubMed ID: 17699591
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membrane.
    Yoshida A; Hayashi H; Tanabe K; Fujita A
    Biochim Biophys Acta Biomembr; 2017 Oct; 1859(10):1880-1890. PubMed ID: 28648675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans.
    Nicot AS; Fares H; Payrastre B; Chisholm AD; Labouesse M; Laporte J
    Mol Biol Cell; 2006 Jul; 17(7):3062-74. PubMed ID: 16801682
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
    Fernandez-Mosquera L; Yambire KF; Couto R; Pereyra L; Pabis K; Ponsford AH; Diogo CV; Stagi M; Milosevic I; Raimundo N
    Autophagy; 2019 Sep; 15(9):1572-1591. PubMed ID: 30917721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
    Compton LM; Ikonomov OC; Sbrissa D; Garg P; Shisheva A
    Am J Physiol Cell Physiol; 2016 Sep; 311(3):C366-77. PubMed ID: 27335171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.
    Bonangelino CJ; Nau JJ; Duex JE; Brinkman M; Wurmser AE; Gary JD; Emr SD; Weisman LS
    J Cell Biol; 2002 Mar; 156(6):1015-28. PubMed ID: 11889142
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Phosphoinositides: lipidic essential actors in the intracellular traffic].
    Bertazzi DL; De Craene JO; Bär S; Sanjuan-Vazquez M; Raess MA; Friant S
    Biol Aujourdhui; 2015; 209(1):97-109. PubMed ID: 26115715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells.
    Chintaluri K; Goulden BD; Clemenza C; Saffi G; Miraglia E; Hammond GRV; Botelho RJ
    PLoS One; 2018; 13(6):e0198454. PubMed ID: 29870544
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
    Sharma G; Guardia CM; Roy A; Vassilev A; Saric A; Griner LN; Marugan J; Ferrer M; Bonifacino JS; DePamphilis ML
    Autophagy; 2019 Oct; 15(10):1694-1718. PubMed ID: 30806145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation.
    Cozier GE; Carlton J; McGregor AH; Gleeson PA; Teasdale RD; Mellor H; Cullen PJ
    J Biol Chem; 2002 Dec; 277(50):48730-6. PubMed ID: 12198132
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2.
    Ho CY; Alghamdi TA; Botelho RJ
    Traffic; 2012 Jan; 13(1):1-8. PubMed ID: 21736686
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.