BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

638 related articles for article (PubMed ID: 19275634)

  • 1. Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.
    Deane R; Bell RD; Sagare A; Zlokovic BV
    CNS Neurol Disord Drug Targets; 2009 Mar; 8(1):16-30. PubMed ID: 19275634
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease.
    Deane R; Sagare A; Zlokovic BV
    Curr Pharm Des; 2008; 14(16):1601-5. PubMed ID: 18673201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.
    Deane R; Sagare A; Hamm K; Parisi M; LaRue B; Guo H; Wu Z; Holtzman DM; Zlokovic BV
    J Neurosci; 2005 Dec; 25(50):11495-503. PubMed ID: 16354907
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of High Cholesterol Regulation of LRP1 and RAGE on Aβ Transport Across the Blood-Brain Barrier in Alzheimer's Disease.
    Zhou R; Chen LL; Yang H; Li L; Liu J; Chen L; Hong WJ; Wang CG; Ma JJ; Huang J; Zhou XF; Liu D; Zhou HD
    Curr Alzheimer Res; 2021; 18(5):428-442. PubMed ID: 34488598
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Low-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.
    Sagare AP; Deane R; Zlokovic BV
    Pharmacol Ther; 2012 Oct; 136(1):94-105. PubMed ID: 22820095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease.
    Deane R; Zlokovic BV
    Curr Alzheimer Res; 2007 Apr; 4(2):191-7. PubMed ID: 17430246
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.
    Qosa H; Abuasal BS; Romero IA; Weksler B; Couraud PO; Keller JN; Kaddoumi A
    Neuropharmacology; 2014 Apr; 79():668-78. PubMed ID: 24467845
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease.
    Jaeger LB; Dohgu S; Sultana R; Lynch JL; Owen JB; Erickson MA; Shah GN; Price TO; Fleegal-Demotta MA; Butterfield DA; Banks WA
    Brain Behav Immun; 2009 May; 23(4):507-17. PubMed ID: 19486646
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport.
    Guo YX; He LY; Zhang M; Wang F; Liu F; Peng WX
    Neuroscience; 2016 May; 322():28-38. PubMed ID: 26820600
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Magnesium Reduces Blood-Brain Barrier Permeability and Regulates Amyloid-β Transcytosis.
    Zhu D; Su Y; Fu B; Xu H
    Mol Neurobiol; 2018 Sep; 55(9):7118-7131. PubMed ID: 29383689
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
    Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
    Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chronic cerebral hypoperfusion alters amyloid-β transport related proteins in the cortical blood vessels of Alzheimer's disease model mouse.
    Shang J; Yamashita T; Tian F; Li X; Liu X; Shi X; Nakano Y; Tsunoda K; Nomura E; Sasaki R; Tadokoro K; Sato K; Takemoto M; Hishikawa N; Ohta Y; Abe K
    Brain Res; 2019 Nov; 1723():146379. PubMed ID: 31415766
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.
    Qosa H; LeVine H; Keller JN; Kaddoumi A
    Biochim Biophys Acta; 2014 Sep; 1842(9):1806-15. PubMed ID: 24997450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro model of the blood-brain barrier.
    Bachmeier CJ; Beaulieu-Abdelahad D; Mullan MJ; Paris D
    Microcirculation; 2011 Jul; 18(5):373-9. PubMed ID: 21418385
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain.
    Sagare AP; Bell RD; Srivastava A; Sengillo JD; Singh I; Nishida Y; Chow N; Zlokovic BV
    J Biol Chem; 2013 May; 288(21):15154-66. PubMed ID: 23580652
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice.
    Bhargavan B; Woollard SM; McMillan JE; Kanmogne GD
    Mol Neurodegener; 2021 Nov; 16(1):78. PubMed ID: 34809709
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of Blood-Brain Barrier in Alzheimer's Disease.
    Cai Z; Qiao PF; Wan CQ; Cai M; Zhou NK; Li Q
    J Alzheimers Dis; 2018; 63(4):1223-1234. PubMed ID: 29782323
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).
    Do TM; Dodacki A; Alata W; Calon F; Nicolic S; Scherrmann JM; Farinotti R; Bourasset F
    J Alzheimers Dis; 2016; 49(2):287-300. PubMed ID: 26484906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier.
    Osgood D; Miller MC; Messier AA; Gonzalez L; Silverberg GD
    Neurobiol Aging; 2017 Sep; 57():178-185. PubMed ID: 28654861
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.