154 related articles for article (PubMed ID: 19276550)
41. Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.
Honarnejad K; Jung CK; Lammich S; Arzberger T; Kretzschmar H; Herms J
J Cell Mol Med; 2013 Feb; 17(2):293-302. PubMed ID: 23379308
[TBL] [Abstract][Full Text] [Related]
42. Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling.
Baki L; Neve RL; Shao Z; Shioi J; Georgakopoulos A; Robakis NK
J Neurosci; 2008 Jan; 28(2):483-90. PubMed ID: 18184791
[TBL] [Abstract][Full Text] [Related]
43. Presenilin-1, mutated in familial Alzheimer's disease, maintains genome stability via a γ-secretase dependent way.
Guo X; Jiang M; Dai X; Shen J; Wang X
DNA Repair (Amst); 2023 Nov; 131():103580. PubMed ID: 37804602
[TBL] [Abstract][Full Text] [Related]
44. Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway.
Marques CA; Keil U; Bonert A; Steiner B; Haass C; Muller WE; Eckert A
J Biol Chem; 2003 Jul; 278(30):28294-302. PubMed ID: 12730216
[TBL] [Abstract][Full Text] [Related]
45. Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Yagi T; Ito D; Okada Y; Akamatsu W; Nihei Y; Yoshizaki T; Yamanaka S; Okano H; Suzuki N
Hum Mol Genet; 2011 Dec; 20(23):4530-9. PubMed ID: 21900357
[TBL] [Abstract][Full Text] [Related]
46. Acetylcholinesterase modulates presenilin-1 levels and γ-secretase activity.
Campanari ML; García-Ayllón MS; Belbin O; Galcerán J; Lleó A; Sáez-Valero J
J Alzheimers Dis; 2014; 41(3):911-24. PubMed ID: 24699279
[TBL] [Abstract][Full Text] [Related]
47. Familial Alzheimer's disease coding mutations reduce Presenilin-1 expression in a novel genomic locus reporter model.
Ahmadi S; Wade-Martins R
Neurobiol Aging; 2014 Feb; 35(2):443.e5-443.e16. PubMed ID: 24011544
[TBL] [Abstract][Full Text] [Related]
48. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
Guo Q; Sebastian L; Sopher BL; Miller MW; Ware CB; Martin GM; Mattson MP
J Neurochem; 1999 Mar; 72(3):1019-29. PubMed ID: 10037473
[TBL] [Abstract][Full Text] [Related]
49. [Familial Alzheimer's disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts].
Shvartsman AL; Sarantseva SV; Runova OL; Talalaeva EI; Vitek MP
Biofizika; 2010; 55(5):862-7. PubMed ID: 21033353
[TBL] [Abstract][Full Text] [Related]
50. Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis.
Tanii H; Ankarcrona M; Flood F; Nilsberth C; Mehta ND; Perez-Tur J; Winblad B; Benedikz E; Cowburn RF
Neuroscience; 2000; 95(2):593-601. PubMed ID: 10658639
[TBL] [Abstract][Full Text] [Related]
51. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis.
Rojas-Charry L; Calero-Martinez S; Morganti C; Morciano G; Park K; Hagel C; Marciniak SJ; Glatzel M; Pinton P; Sepulveda-Falla D
Sci Rep; 2020 Apr; 10(1):6455. PubMed ID: 32296078
[TBL] [Abstract][Full Text] [Related]
52. [Potential role of presenilin 1 in regulation of synaptic function].
Shvartsman AL; Sarantseva SV; Vitek MP
Tsitologiia; 2011; 53(12):959-67. PubMed ID: 22359955
[TBL] [Abstract][Full Text] [Related]
53. γ-Secretase-dependent cleavage of E-cadherin by staurosporine in breast cancer cells.
Yoo CB; Yun SM; Jo C; Koh YH
Cell Commun Adhes; 2012 Feb; 19(1):11-6. PubMed ID: 22401168
[TBL] [Abstract][Full Text] [Related]
54. Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.
Bruban J; Voloudakis G; Huang Q; Kajiwara Y; Al Rahim M; Yoon Y; Shioi J; Gama Sosa MA; Shao Z; Georgakopoulos A; Robakis NK
FASEB J; 2015 Sep; 29(9):3702-12. PubMed ID: 25985800
[TBL] [Abstract][Full Text] [Related]
55. Gamma-secretase complexes regulate the responses of human pancreatic ductal adenocarcinoma cells to taxanes.
Tasaka T; Akiyoshi T; Yamaguchi K; Tanaka M; Onishi H; Katano M
Anticancer Res; 2010 Dec; 30(12):4999-5010. PubMed ID: 21187481
[TBL] [Abstract][Full Text] [Related]
56. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease.
Kim TW; Pettingell WH; Jung YK; Kovacs DM; Tanzi RE
Science; 1997 Jul; 277(5324):373-6. PubMed ID: 9219695
[TBL] [Abstract][Full Text] [Related]
57. Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
van de Craen M; de Jonghe C; van den Brande I; Declercq W; van Gassen G; van Criekinge W; Vanderhoeven I; Fiers W; van Broeckhoven C; Hendriks L; Vandenabeele P
FEBS Lett; 1999 Feb; 445(1):149-54. PubMed ID: 10069390
[TBL] [Abstract][Full Text] [Related]
58. The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities.
Rohn TT
Apoptosis; 2010 Nov; 15(11):1403-9. PubMed ID: 20127416
[TBL] [Abstract][Full Text] [Related]
59. Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling.
Chong CM; Ke M; Tan Y; Huang Z; Zhang K; Ai N; Ge W; Qin D; Lu JH; Su H
Cell Death Dis; 2018 Aug; 9(9):879. PubMed ID: 30158533
[TBL] [Abstract][Full Text] [Related]
60. Fibroblasts from PS1 mutated pre-symptomatic subjects and Alzheimer's disease patients share a unique protein levels profile.
Magini A; Urbanelli L; Ciccarone V; Tancini B; Polidoro M; Timperio AM; Zolla L; Tedde A; Sorbi S; Emiliani C
J Alzheimers Dis; 2010; 21(2):431-44. PubMed ID: 20555143
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]