BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 19279002)

  • 21. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.
    Cullinan SB; Gordan JD; Jin J; Harper JW; Diehl JA
    Mol Cell Biol; 2004 Oct; 24(19):8477-86. PubMed ID: 15367669
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
    Baird L; Dinkova-Kostova AT
    Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Aromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer.
    Khatri R; Shah P; Guha R; Rassool FV; Tomkinson AE; Brodie A; Jaiswal AK
    Mol Cancer Ther; 2015 Jul; 14(7):1728-37. PubMed ID: 25976679
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
    Stępkowski TM; Kruszewski MK
    Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
    Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
    Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.
    Martinez VD; Vucic EA; Pikor LA; Thu KL; Hubaux R; Lam WL
    Mol Cancer; 2013 Oct; 12(1):124. PubMed ID: 24138990
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cysteine-based regulation of the CUL3 adaptor protein Keap1.
    Sekhar KR; Rachakonda G; Freeman ML
    Toxicol Appl Pharmacol; 2010 Apr; 244(1):21-6. PubMed ID: 19560482
    [TBL] [Abstract][Full Text] [Related]  

  • 28. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
    Furukawa M; Xiong Y
    Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
    McMahon M; Swift SR; Hayes JD
    Toxicol Appl Pharmacol; 2018 Dec; 360():45-57. PubMed ID: 30261176
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes.
    Ichikawa T; Li J; Meyer CJ; Janicki JS; Hannink M; Cui T
    PLoS One; 2009 Dec; 4(12):e8391. PubMed ID: 20027226
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.
    Niture SK; Jain AK; Jaiswal AK
    J Cell Sci; 2009 Dec; 122(Pt 24):4452-64. PubMed ID: 19920073
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Nuclear import and export signals in control of Nrf2.
    Jain AK; Bloom DA; Jaiswal AK
    J Biol Chem; 2005 Aug; 280(32):29158-68. PubMed ID: 15901726
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Fuzzy complex formation between the intrinsically disordered prothymosin α and the Kelch domain of Keap1 involved in the oxidative stress response.
    Khan H; Cino EA; Brickenden A; Fan J; Yang D; Choy WY
    J Mol Biol; 2013 Mar; 425(6):1011-27. PubMed ID: 23318954
    [TBL] [Abstract][Full Text] [Related]  

  • 34. p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.
    Tao S; Liu P; Luo G; Rojo de la Vega M; Chen H; Wu T; Tillotson J; Chapman E; Zhang DD
    Mol Cell Biol; 2017 Apr; 37(8):. PubMed ID: 28115426
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
    Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
    Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2 signaling in human bladder cancer.
    Tsai YS; Jou YC; Tsai HT; Shiau AL; Wu CL; Tzai TS
    Cancer Sci; 2019 Apr; 110(4):1208-1219. PubMed ID: 30719818
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structural analysis of the complex of Keap1 with a prothymosin alpha peptide.
    Padmanabhan B; Nakamura Y; Yokoyama S
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Apr; 64(Pt 4):233-8. PubMed ID: 18391415
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [Influence of prothymosin alpha and its mutants on activity of the p53 tumor suppressor].
    Zakharova NI; Sokolov VV; Rud'ko VV; Mel'nikov SV; Vartapetian AB; Evstaf'eva AG
    Mol Biol (Mosk); 2008; 42(4):673-84. PubMed ID: 18856068
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.
    McMahon M; Thomas N; Itoh K; Yamamoto M; Hayes JD
    J Biol Chem; 2006 Aug; 281(34):24756-68. PubMed ID: 16790436
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway.
    Hayes JD; McMahon M; Chowdhry S; Dinkova-Kostova AT
    Antioxid Redox Signal; 2010 Dec; 13(11):1713-48. PubMed ID: 20446772
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.