BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 19282188)

  • 1. Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers.
    Zhang HZ; Crogan-Grundy C; May C; Drewe J; Tseng B; Cai SX
    Bioorg Med Chem; 2009 Apr; 17(7):2852-8. PubMed ID: 19282188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions.
    Kemnitzer W; Kuemmerle J; Jiang S; Zhang HZ; Sirisoma N; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6259-64. PubMed ID: 18952423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers.
    Kemnitzer W; Sirisoma N; May C; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3536-40. PubMed ID: 19464890
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions.
    Kemnitzer W; Drewe J; Jiang S; Zhang H; Crogan-Grundy C; Labreque D; Bubenick M; Attardo G; Denis R; Lamothe S; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
    J Med Chem; 2008 Feb; 51(3):417-23. PubMed ID: 18197614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.
    Kemnitzer W; Drewe J; Jiang S; Zhang H; Wang Y; Zhao J; Jia S; Herich J; Labreque D; Storer R; Meerovitch K; Bouffard D; Rej R; Denis R; Blais C; Lamothe S; Attardo G; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
    J Med Chem; 2004 Dec; 47(25):6299-310. PubMed ID: 15566300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay.
    Cai SX; Nguyen B; Jia S; Herich J; Guastella J; Reddy S; Tseng B; Drewe J; Kasibhatla S
    J Med Chem; 2003 Jun; 46(12):2474-81. PubMed ID: 12773051
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay.
    Drewe J; Kasibhatla S; Tseng B; Shelton E; Sperandio D; Yee RM; Litvak J; Sendzik M; Spencer JR; Cai SX
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4987-90. PubMed ID: 17562361
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions.
    Kemnitzer W; Kuemmerle J; Jiang S; Sirisoma N; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3481-4. PubMed ID: 19467598
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and structure-activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers.
    Zhang HZ; Claassen G; Crogran-Grundy C; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem; 2008 Jan; 16(1):222-31. PubMed ID: 17950608
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.
    Sirisoma N; Kasibhatla S; Nguyen B; Pervin A; Wang Y; Claassen G; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem; 2006 Dec; 14(23):7761-73. PubMed ID: 16919962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide group.
    Kemnitzer W; Sirisoma N; Nguyen B; Jiang S; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem Lett; 2009 Jun; 19(11):3045-9. PubMed ID: 19394823
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
    J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization.
    Prakasham AP; Saxena AK; Luqman S; Chanda D; Kaur T; Gupta A; Yadav DK; Chanotiya CS; Shanker K; Khan F; Negi AS
    Bioorg Med Chem; 2012 May; 20(9):3049-57. PubMed ID: 22472045
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.
    Zhang HZ; Drewe J; Tseng B; Kasibhatla S; Cai SX
    Bioorg Med Chem; 2004 Jul; 12(13):3649-55. PubMed ID: 15186849
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure-activity relationships of the 2-aryl group.
    Sirisoma N; Pervin A; Nguyen B; Crogan-Grundy C; Kasibhatla S; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2305-9. PubMed ID: 19285392
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Benzoylphenylurea sulfur analogues with potent antitumor activity.
    Hallur G; Jimeno A; Dalrymple S; Zhu T; Jung MK; Hidalgo M; Isaacs JT; Sukumar S; Hamel E; Khan SR
    J Med Chem; 2006 Apr; 49(7):2357-60. PubMed ID: 16570932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay.
    Jiang S; Crogan-Grundy C; Drewe J; Tseng B; Cai SX
    Bioorg Med Chem Lett; 2008 Nov; 18(21):5725-8. PubMed ID: 18849165
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X; Chen X; Piatnitski EL; Kiselyov AS; He HY; Mao Y; Pattaropong V; Yu Y; Kim KH; Kincaid J; Smith L; Wong WC; Lee SP; Milligan DL; Malikzay A; Fleming J; Gerlak J; Deevi D; Doody JF; Chiang HH; Patel SN; Wang Y; Rolser RL; Kussie P; Labelle M; Tuma MC
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5154-9. PubMed ID: 16198562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.