411 related articles for article (PubMed ID: 19284751)
1. Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
O'Neill PM; Shone AE; Stanford D; Nixon G; Asadollahy E; Park BK; Maggs JL; Roberts P; Stocks PA; Biagini G; Bray PG; Davies J; Berry N; Hall C; Rimmer K; Winstanley PA; Hindley S; Bambal RB; Davis CB; Bates M; Gresham SL; Brigandi RA; Gomez-de-Las-Heras FM; Gargallo DV; Parapini S; Vivas L; Lander H; Taramelli D; Ward SA
J Med Chem; 2009 Apr; 52(7):1828-44. PubMed ID: 19284751
[TBL] [Abstract][Full Text] [Related]
2. Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials.
O'Neill PM; Mukhtar A; Stocks PA; Randle LE; Hindley S; Ward SA; Storr RC; Bickley JF; O'Neil IA; Maggs JL; Hughes RH; Winstanley PA; Bray PG; Park BK
J Med Chem; 2003 Nov; 46(23):4933-45. PubMed ID: 14584944
[TBL] [Abstract][Full Text] [Related]
3. Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
O'Neill PM; Park BK; Shone AE; Maggs JL; Roberts P; Stocks PA; Biagini GA; Bray PG; Gibbons P; Berry N; Winstanley PA; Mukhtar A; Bonar-Law R; Hindley S; Bambal RB; Davis CB; Bates M; Hart TK; Gresham SL; Lawrence RM; Brigandi RA; Gomez-delas-Heras FM; Gargallo DV; Ward SA
J Med Chem; 2009 Mar; 52(5):1408-15. PubMed ID: 19222165
[TBL] [Abstract][Full Text] [Related]
4. 4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity.
Sparatore A; Basilico N; Parapini S; Romeo S; Novelli F; Sparatore F; Taramelli D
Bioorg Med Chem; 2005 Sep; 13(18):5338-45. PubMed ID: 16054368
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues.
O'Neill PM; Willock DJ; Hawley SR; Bray PG; Storr RC; Ward SA; Park BK
J Med Chem; 1997 Feb; 40(4):437-48. PubMed ID: 9046333
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and antimalarial activity of side chain modified 4-aminoquinoline derivatives.
Solomon VR; Haq W; Srivastava K; Puri SK; Katti SB
J Med Chem; 2007 Jan; 50(2):394-8. PubMed ID: 17228883
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.
Biot C; Glorian G; Maciejewski LA; Brocard JS
J Med Chem; 1997 Nov; 40(23):3715-8. PubMed ID: 9371235
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of new antimalarial agents from 4-aminoquinoline.
Solomon VR; Puri SK; Srivastava K; Katti SB
Bioorg Med Chem; 2005 Mar; 13(6):2157-65. PubMed ID: 15727868
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and evaluation of phenylequine for antimalarial activity in vitro and in vivo.
Blackie MA; Yardley V; Chibale K
Bioorg Med Chem Lett; 2010 Feb; 20(3):1078-80. PubMed ID: 20034790
[TBL] [Abstract][Full Text] [Related]
10. Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
Gemma S; Camodeca C; Sanna Coccone S; Joshi BP; Bernetti M; Moretti V; Brogi S; Bonache de Marcos MC; Savini L; Taramelli D; Basilico N; Parapini S; Rottmann M; Brun R; Lamponi S; Caccia S; Guiso G; Summers RL; Martin RE; Saponara S; Gorelli B; Novellino E; Campiani G; Butini S
J Med Chem; 2012 Aug; 55(15):6948-67. PubMed ID: 22783984
[TBL] [Abstract][Full Text] [Related]
11. Novel amodiaquine congeners as potent antimalarial agents.
Casagrande M; Basilico N; Parapini S; Romeo S; Taramelli D; Sparatore A
Bioorg Med Chem; 2008 Jul; 16(14):6813-23. PubMed ID: 18562202
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and antimalarial activity of new analogues of amodiaquine.
Delarue-Cochin S; Paunescu E; Maes L; Mouray E; Sergheraert C; Grellier P; Melnyk P
Eur J Med Chem; 2008 Feb; 43(2):252-60. PubMed ID: 17485145
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and blood-schizontocidal antimalarial activities of 2-substituted/2,5-disubstituted-8-quinolinamines and some of their amino acid conjugates.
Jain M; Vangapandu S; Sachdeva S; Jain R
Bioorg Med Chem; 2004 Mar; 12(5):1003-10. PubMed ID: 14980613
[TBL] [Abstract][Full Text] [Related]
14. Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline.
Sparatore A; Basilico N; Casagrande M; Parapini S; Taramelli D; Brun R; Wittlin S; Sparatore F
Bioorg Med Chem Lett; 2008 Jul; 18(13):3737-40. PubMed ID: 18538567
[TBL] [Abstract][Full Text] [Related]
15. Discovery of a bulky 2-tert-butyl group containing primaquine analogue that exhibits potent blood-schizontocidal antimalarial activities and complete elimination of methemoglobin toxicity.
Jain M; Vangapandu S; Sachdeva S; Singh S; Singh PP; Jena GB; Tikoo K; Ramarao P; Kaul CL; Jain R
J Med Chem; 2004 Jan; 47(2):285-7. PubMed ID: 14711300
[TBL] [Abstract][Full Text] [Related]
16. Replacement of the 4'-hydroxy group of amodiaquine and amopyroquine by aromatic and aliphatic substituents: synthesis and antimalarial activity.
Păunescu E; Susplugas S; Boll E; Varga R; Mouray E; Grosu I; Grellier P; Melnyk P
ChemMedChem; 2009 Apr; 4(4):549-61. PubMed ID: 19212949
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and Evaluation of Chirally Defined Side Chain Variants of 7-Chloro-4-Aminoquinoline To Overcome Drug Resistance in Malaria Chemotherapy.
Dola VR; Soni A; Agarwal P; Ahmad H; Raju KS; Rashid M; Wahajuddin M; Srivastava K; Haq W; Dwivedi AK; Puri SK; Katti SB
Antimicrob Agents Chemother; 2017 Mar; 61(3):. PubMed ID: 27956423
[TBL] [Abstract][Full Text] [Related]
18. Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives.
Shiraki H; Kozar MP; Melendez V; Hudson TH; Ohrt C; Magill AJ; Lin AJ
J Med Chem; 2011 Jan; 54(1):131-42. PubMed ID: 21141892
[TBL] [Abstract][Full Text] [Related]
19. Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin.
Perić M; Fajdetić A; Rupčić R; Alihodžić S; Ziher D; Bukvić Krajačić M; Smith KS; Ivezić-Schönfeld Z; Padovan J; Landek G; Jelić D; Hutinec A; Mesić M; Ager A; Ellis WY; Milhous WK; Ohrt C; Spaventi R
J Med Chem; 2012 Feb; 55(3):1389-401. PubMed ID: 22148880
[TBL] [Abstract][Full Text] [Related]
20. 4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake.
Bray PG; Hawley SR; Ward SA
Mol Pharmacol; 1996 Dec; 50(6):1551-8. PubMed ID: 8967977
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
