BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 19290861)

  • 1. Conformational changes in the catalytic cycle of protochlorophyllide oxidoreductase: what lessons can be learnt from dihydrofolate reductase?
    Heyes DJ; Scrutton NS
    Biochem Soc Trans; 2009 Apr; 37(Pt 2):354-7. PubMed ID: 19290861
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational events during ternary enzyme-substrate complex formation are rate limiting in the catalytic cycle of the light-driven enzyme protochlorophyllide oxidoreductase.
    Heyes DJ; Menon BR; Sakuma M; Scrutton NS
    Biochemistry; 2008 Oct; 47(41):10991-8. PubMed ID: 18798649
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR).
    Menon BR; Hardman SJ; Scrutton NS; Heyes DJ
    J Photochem Photobiol B; 2016 Aug; 161():236-43. PubMed ID: 27285815
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and characterization of the product release steps within the catalytic cycle of protochlorophyllide oxidoreductase.
    Heyes DJ; Hunter CN
    Biochemistry; 2004 Jun; 43(25):8265-71. PubMed ID: 15209523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ultrafast catalytic processes and conformational changes in the light-driven enzyme protochlorophyllide oxidoreductase (POR).
    Sytina OA; Heyes DJ; Hunter CN; Groot ML
    Biochem Soc Trans; 2009 Apr; 37(Pt 2):387-91. PubMed ID: 19290868
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis.
    Zhang S; Heyes DJ; Feng L; Sun W; Johannissen LO; Liu H; Levy CW; Li X; Yang J; Yu X; Lin M; Hardman SJO; Hoeven R; Sakuma M; Hay S; Leys D; Rao Z; Zhou A; Cheng Q; Scrutton NS
    Nature; 2019 Oct; 574(7780):722-725. PubMed ID: 31645759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Making light work of enzyme catalysis: protochlorophyllide oxidoreductase.
    Heyes DJ; Hunter CN
    Trends Biochem Sci; 2005 Nov; 30(11):642-9. PubMed ID: 16182531
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzyme activation and catalysis: characterisation of the vibrational modes of substrate and product in protochlorophyllide oxidoreductase.
    Sytina OA; Alexandre MT; Heyes DJ; Hunter CN; Robert B; van Grondelle R; Groot ML
    Phys Chem Chem Phys; 2011 Feb; 13(6):2307-13. PubMed ID: 21103538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spectroscopic and kinetic characterization of the light-dependent enzyme protochlorophyllide oxidoreductase (POR) using monovinyl and divinyl substrates.
    Heyes DJ; Kruk J; Hunter CN
    Biochem J; 2006 Feb; 394(Pt 1):243-8. PubMed ID: 16274361
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual role of the active site 'lid' regions of protochlorophyllide oxidoreductase in photocatalysis and plant development.
    Zhang S; Godwin ARF; Taylor A; Hardman SJO; Jowitt TA; Johannissen LO; Hay S; Baldock C; Heyes DJ; Scrutton NS
    FEBS J; 2021 Jan; 288(1):175-189. PubMed ID: 32866986
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase.
    Taylor A; Zhang S; Johannissen LO; Sakuma M; Phillips RS; Green AP; Hay S; Heyes DJ; Scrutton NS
    FEBS J; 2024 Apr; 291(7):1404-1421. PubMed ID: 38060334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis alters the catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase.
    Menon BR; Davison PA; Hunter CN; Scrutton NS; Heyes DJ
    J Biol Chem; 2010 Jan; 285(3):2113-9. PubMed ID: 19850924
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic reappraisal of early stage photochemistry in the light-driven enzyme protochlorophyllide oxidoreductase.
    Heyes DJ; Hardman SJ; Mansell D; Gardiner JM; Scrutton NS
    PLoS One; 2012; 7(9):e45642. PubMed ID: 23049830
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The first catalytic step of the light-driven enzyme protochlorophyllide oxidoreductase proceeds via a charge transfer complex.
    Heyes DJ; Heathcote P; Rigby SE; Palacios MA; van Grondelle R; Hunter CN
    J Biol Chem; 2006 Sep; 281(37):26847-53. PubMed ID: 16867988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Light-Dependent Protochlorophyllide Oxidoreductase: Phylogeny, Regulation, and Catalytic Properties.
    Gabruk M; Mysliwa-Kurdziel B
    Biochemistry; 2015 Sep; 54(34):5255-62. PubMed ID: 26230427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protochlorophyllide oxidoreductase: "dark" reactions of a light-driven enzyme.
    Heyes DJ; Ruban AV; Hunter CN
    Biochemistry; 2003 Jan; 42(2):523-8. PubMed ID: 12525180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase.
    Menon BR; Waltho JP; Scrutton NS; Heyes DJ
    J Biol Chem; 2009 Jul; 284(27):18160-6. PubMed ID: 19439417
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Plant Protochlorophyllide Oxidoreductases A and B: CATALYTIC EFFICIENCY AND INITIAL REACTION STEPS.
    Garrone A; Archipowa N; Zipfel PF; Hermann G; Dietzek B
    J Biol Chem; 2015 Nov; 290(47):28530-28539. PubMed ID: 26408201
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enzymology below 200 K: the kinetics and thermodynamics of the photochemistry catalyzed by protochlorophyllide oxidoreductase.
    Heyes DJ; Ruban AV; Wilks HM; Hunter CN
    Proc Natl Acad Sci U S A; 2002 Aug; 99(17):11145-50. PubMed ID: 12177453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tyr275 and Lys279 stabilize NADPH within the catalytic site of NADPH:protochlorophyllide oxidoreductase and are involved in the formation of the enzyme photoactive state.
    Lebedev N; Karginova O; McIvor W; Timko MP
    Biochemistry; 2001 Oct; 40(42):12562-74. PubMed ID: 11601980
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.