215 related articles for article (PubMed ID: 19293266)
1. Inhibition of Src with AZD0530 reveals the Src-Focal Adhesion kinase complex as a novel therapeutic target in papillary and anaplastic thyroid cancer.
Schweppe RE; Kerege AA; French JD; Sharma V; Grzywa RL; Haugen BR
J Clin Endocrinol Metab; 2009 Jun; 94(6):2199-203. PubMed ID: 19293266
[TBL] [Abstract][Full Text] [Related]
2. Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530.
Chang YM; Bai L; Liu S; Yang JC; Kung HJ; Evans CP
Oncogene; 2008 Oct; 27(49):6365-75. PubMed ID: 18679417
[TBL] [Abstract][Full Text] [Related]
3. Antitumor effects and biomarkers of activity of AZD0530, a Src inhibitor, in pancreatic cancer.
Rajeshkumar NV; Tan AC; De Oliveira E; Womack C; Wombwell H; Morgan S; Warren MV; Walker J; Green TP; Jimeno A; Messersmith WA; Hidalgo M
Clin Cancer Res; 2009 Jun; 15(12):4138-46. PubMed ID: 19509160
[TBL] [Abstract][Full Text] [Related]
4. Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530.
Green TP; Fennell M; Whittaker R; Curwen J; Jacobs V; Allen J; Logie A; Hargreaves J; Hickinson DM; Wilkinson RW; Elvin P; Boyer B; Carragher N; Plé PA; Bermingham A; Holdgate GA; Ward WH; Hennequin LF; Davies BR; Costello GF
Mol Oncol; 2009 Jun; 3(3):248-61. PubMed ID: 19393585
[TBL] [Abstract][Full Text] [Related]
5. Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity.
Ciccimaro E; Hanks SK; Blair IA
Mol Pharmacol; 2009 Mar; 75(3):658-66. PubMed ID: 19098120
[TBL] [Abstract][Full Text] [Related]
6. Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer.
Schiff BA; McMurphy AB; Jasser SA; Younes MN; Doan D; Yigitbasi OG; Kim S; Zhou G; Mandal M; Bekele BN; Holsinger FC; Sherman SI; Yeung SC; El-Naggar AK; Myers JN
Clin Cancer Res; 2004 Dec; 10(24):8594-602. PubMed ID: 15623643
[TBL] [Abstract][Full Text] [Related]
7. Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src.
Lee YH; Kayyali US; Sousa AM; Rajan T; Lechleider RJ; Day RM
Am J Respir Cell Mol Biol; 2007 Oct; 37(4):485-93. PubMed ID: 17585111
[TBL] [Abstract][Full Text] [Related]
8. Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways.
Acosta JJ; Muñoz RM; González L; Subtil-Rodríguez A; Dominguez-Caceres MA; García-Martínez JM; Calcabrini A; Lazaro-Trueba I; Martín-Pérez J
Mol Endocrinol; 2003 Nov; 17(11):2268-82. PubMed ID: 12907754
[TBL] [Abstract][Full Text] [Related]
9. TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR.
Golubovskaya VM; Virnig C; Cance WG
Mol Carcinog; 2008 Mar; 47(3):222-34. PubMed ID: 17849451
[TBL] [Abstract][Full Text] [Related]
10. IGFBP2/FAK pathway is causally associated with dasatinib resistance in non-small cell lung cancer cells.
Lu H; Wang L; Gao W; Meng J; Dai B; Wu S; Minna J; Roth JA; Hofstetter WL; Swisher SG; Fang B
Mol Cancer Ther; 2013 Dec; 12(12):2864-73. PubMed ID: 24130049
[TBL] [Abstract][Full Text] [Related]
11. Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line.
Caccia D; Miccichè F; Cassinelli G; Mondellini P; Casalini P; Bongarzone I
Mol Cancer; 2010 Oct; 9():278. PubMed ID: 20955590
[TBL] [Abstract][Full Text] [Related]
12. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events.
Schlaepfer DD; Jones KC; Hunter T
Mol Cell Biol; 1998 May; 18(5):2571-85. PubMed ID: 9566877
[TBL] [Abstract][Full Text] [Related]
13. Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model.
Yang JC; Bai L; Yap S; Gao AC; Kung HJ; Evans CP
Mol Cancer Ther; 2010 Jun; 9(6):1629-37. PubMed ID: 20484016
[TBL] [Abstract][Full Text] [Related]
14. A phase II trial of the Src-kinase inhibitor AZD0530 in patients with advanced castration-resistant prostate cancer: a California Cancer Consortium study.
Lara PN; Longmate J; Evans CP; Quinn DI; Twardowski P; Chatta G; Posadas E; Stadler W; Gandara DR
Anticancer Drugs; 2009 Mar; 20(3):179-84. PubMed ID: 19396016
[TBL] [Abstract][Full Text] [Related]
15. The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells.
Purnell PR; Mack PC; Tepper CG; Evans CP; Green TP; Gumerlock PH; Lara PN; Gandara DR; Kung HJ; Gautschi O
J Thorac Oncol; 2009 Apr; 4(4):448-54. PubMed ID: 19240653
[TBL] [Abstract][Full Text] [Related]
16. Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition.
Schweppe RE; Kerege AA; Sharma V; Poczobutt JM; Gutierrez-Hartmann A; Grzywa RL; Haugen BR
Thyroid; 2009 Aug; 19(8):825-35. PubMed ID: 19500021
[TBL] [Abstract][Full Text] [Related]
17. Src inhibitors in suppression of papillary thyroid carcinoma growth.
Henderson YC; Toro-Serra R; Chen Y; Ryu J; Frederick MJ; Zhou G; Gallick GE; Lai SY; Clayman GL
Head Neck; 2014 Mar; 36(3):375-84. PubMed ID: 23729178
[TBL] [Abstract][Full Text] [Related]
18. The Src inhibitor AZD0530 reversibly inhibits the formation and activity of human osteoclasts.
de Vries TJ; Mullender MG; van Duin MA; Semeins CM; James N; Green TP; Everts V; Klein-Nulend J
Mol Cancer Res; 2009 Apr; 7(4):476-88. PubMed ID: 19372577
[TBL] [Abstract][Full Text] [Related]
19. The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism.
Franzen CA; Amargo E; Todorović V; Desai BV; Huda S; Mirzoeva S; Chiu K; Grzybowski BA; Chew TL; Green KJ; Pelling JC
Cancer Prev Res (Phila); 2009 Sep; 2(9):830-41. PubMed ID: 19737984
[TBL] [Abstract][Full Text] [Related]
20. Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.
de Paula CAA; Coulson-Thomas VJ; Ferreira JG; Maza PK; Suzuki E; Nakahata AM; Nader HB; Sampaio MU; Oliva MLV
J Biol Chem; 2012 Jan; 287(1):170-182. PubMed ID: 22039045
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
