358 related articles for article (PubMed ID: 19295164)
21. Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis.
Kim J; Jiang H; Park S; Eltorai AE; Stewart FR; Yoon H; Basak JM; Finn MB; Holtzman DM
J Neurosci; 2011 Dec; 31(49):18007-12. PubMed ID: 22159114
[TBL] [Abstract][Full Text] [Related]
22. A Novel Apolipoprotein E Antagonist Functionally Blocks Apolipoprotein E Interaction With N-terminal Amyloid Precursor Protein, Reduces β-Amyloid-Associated Pathology, and Improves Cognition.
Sawmiller D; Habib A; Hou H; Mori T; Fan A; Tian J; Zeng J; Giunta B; Sanberg PR; Mattson MP; Tan J
Biol Psychiatry; 2019 Aug; 86(3):208-220. PubMed ID: 31208706
[TBL] [Abstract][Full Text] [Related]
23. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Deane R; Sagare A; Hamm K; Parisi M; Lane S; Finn MB; Holtzman DM; Zlokovic BV
J Clin Invest; 2008 Dec; 118(12):4002-13. PubMed ID: 19033669
[TBL] [Abstract][Full Text] [Related]
24. APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.
Youmans KL; Tai LM; Nwabuisi-Heath E; Jungbauer L; Kanekiyo T; Gan M; Kim J; Eimer WA; Estus S; Rebeck GW; Weeber EJ; Bu G; Yu C; Ladu MJ
J Biol Chem; 2012 Dec; 287(50):41774-86. PubMed ID: 23060451
[TBL] [Abstract][Full Text] [Related]
25. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Castellano JM; Kim J; Stewart FR; Jiang H; DeMattos RB; Patterson BW; Fagan AM; Morris JC; Mawuenyega KG; Cruchaga C; Goate AM; Bales KR; Paul SM; Bateman RJ; Holtzman DM
Sci Transl Med; 2011 Jun; 3(89):89ra57. PubMed ID: 21715678
[TBL] [Abstract][Full Text] [Related]
26. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
Aleshkov S; Abraham CR; Zannis VI
Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
[TBL] [Abstract][Full Text] [Related]
27. The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
Fryer JD; Demattos RB; McCormick LM; O'Dell MA; Spinner ML; Bales KR; Paul SM; Sullivan PM; Parsadanian M; Bu G; Holtzman DM
J Biol Chem; 2005 Jul; 280(27):25754-9. PubMed ID: 15888448
[TBL] [Abstract][Full Text] [Related]
28. The interaction of amyloid-beta with ApoE.
Carter DB
Subcell Biochem; 2005; 38():255-72. PubMed ID: 15709483
[TBL] [Abstract][Full Text] [Related]
29. Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer's mice.
Sawmiller D; Koyama N; Fujiwara M; Segawa T; Maeda M; Mori T
J Biol Chem; 2023 Jul; 299(7):104846. PubMed ID: 37211092
[TBL] [Abstract][Full Text] [Related]
30. Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.
Bales KR; Verina T; Cummins DJ; Du Y; Dodel RC; Saura J; Fishman CE; DeLong CA; Piccardo P; Petegnief V; Ghetti B; Paul SM
Proc Natl Acad Sci U S A; 1999 Dec; 96(26):15233-8. PubMed ID: 10611368
[TBL] [Abstract][Full Text] [Related]
31. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
[TBL] [Abstract][Full Text] [Related]
32. Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain.
Carter DB; Dunn E; McKinley DD; Stratman NC; Boyle TP; Kuiper SL; Oostveen JA; Weaver RJ; Boller JA; Gurney ME
Ann Neurol; 2001 Oct; 50(4):468-75. PubMed ID: 11601499
[TBL] [Abstract][Full Text] [Related]
33. Apolipoprotein E isoform-dependent effects on the processing of Alzheimer's amyloid-β.
Chai AB; Lam HHJ; Kockx M; Gelissen IC
Biochim Biophys Acta Mol Cell Biol Lipids; 2021 Sep; 1866(9):158980. PubMed ID: 34044125
[TBL] [Abstract][Full Text] [Related]
34. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
[TBL] [Abstract][Full Text] [Related]
35. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice.
Xu F; Vitek MP; Colton CA; Previti ML; Gharkholonarehe N; Davis J; Van Nostrand WE
J Neurosci; 2008 May; 28(20):5312-20. PubMed ID: 18480287
[TBL] [Abstract][Full Text] [Related]
36. Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer's Disease.
Nakamura T; Kawarabayashi T; Ueda T; Shimomura S; Hoshino M; Itoh K; Ihara K; Nakaji S; Takatama M; Ikeda Y; Shoji M
J Alzheimers Dis; 2023; 93(1):333-348. PubMed ID: 36970894
[TBL] [Abstract][Full Text] [Related]
37. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
Arold S; Sullivan P; Bilousova T; Teng E; Miller CA; Poon WW; Vinters HV; Cornwell LB; Saing T; Cole GM; Gylys KH
Acta Neuropathol; 2012 Jan; 123(1):39-52. PubMed ID: 22020632
[TBL] [Abstract][Full Text] [Related]
38. Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.
Pankiewicz JE; Guridi M; Kim J; Asuni AA; Sanchez S; Sullivan PM; Holtzman DM; Sadowski MJ
Acta Neuropathol Commun; 2014 Jun; 2():75. PubMed ID: 24972680
[TBL] [Abstract][Full Text] [Related]
39. A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade.
Dolev I; Michaelson DM
Proc Natl Acad Sci U S A; 2004 Sep; 101(38):13909-14. PubMed ID: 15365176
[TBL] [Abstract][Full Text] [Related]
40. Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.
Wahrle SE; Jiang H; Parsadanian M; Hartman RE; Bales KR; Paul SM; Holtzman DM
J Biol Chem; 2005 Dec; 280(52):43236-42. PubMed ID: 16207708
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]