244 related articles for article (PubMed ID: 19299147)
21. N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.
Matesic L; Locke JM; Bremner JB; Pyne SG; Skropeta D; Ranson M; Vine KL
Bioorg Med Chem; 2008 Mar; 16(6):3118-24. PubMed ID: 18182300
[TBL] [Abstract][Full Text] [Related]
22. Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.
Chen LR; Wang YC; Lin YW; Chou SY; Chen SF; Liu LT; Wu YT; Kuo CJ; Chen TS; Juang SH
Bioorg Med Chem Lett; 2005 Jun; 15(12):3058-62. PubMed ID: 15896959
[TBL] [Abstract][Full Text] [Related]
23. Synthesis and evaluation of vinyl sulfones as caspase-3 inhibitors. A structure-activity study.
Newton AS; Glória PM; Gonçalves LM; dos Santos DJ; Moreira R; Guedes RC; Santos MM
Eur J Med Chem; 2010 Sep; 45(9):3858-63. PubMed ID: 20541849
[TBL] [Abstract][Full Text] [Related]
24. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.
Kravchenko DV; Kuzovkova YA; Kysil VM; Tkachenko SE; Maliarchouk S; Okun IM; Balakin KV; Ivachtchenko AV
J Med Chem; 2005 Jun; 48(11):3680-3. PubMed ID: 15916416
[TBL] [Abstract][Full Text] [Related]
25. Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.
Zhou D; Chu W; Rothfuss J; Zeng C; Xu J; Jones L; Welch MJ; Mach RH
Bioorg Med Chem Lett; 2006 Oct; 16(19):5041-6. PubMed ID: 16891117
[TBL] [Abstract][Full Text] [Related]
26. Synthesis of new sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Cheng XC; Wang Q; Fang H; Tang W; Xu WF
Bioorg Med Chem; 2008 Sep; 16(17):7932-8. PubMed ID: 18718763
[TBL] [Abstract][Full Text] [Related]
27. Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors.
González A; Quirante J; Nieto J; Almeida MR; Saraiva MJ; Planas A; Arsequell G; Valencia G
Bioorg Med Chem Lett; 2009 Sep; 19(17):5270-3. PubMed ID: 19651509
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain.
Chiyanzu I; Hansell E; Gut J; Rosenthal PJ; McKerrow JH; Chibale K
Bioorg Med Chem Lett; 2003 Oct; 13(20):3527-30. PubMed ID: 14505663
[TBL] [Abstract][Full Text] [Related]
29. Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) do not inhibit caspase-3 and caspase-7 processing in cells exposed to pro-apoptotic inducing stimuli.
Frydrych I; Mlejnek P
J Cell Biochem; 2008 Dec; 105(6):1501-6. PubMed ID: 18980241
[TBL] [Abstract][Full Text] [Related]
30. Biochemical and biophysical characterization of inhibitor binding to caspase-3 reveals induced asymmetry.
Aulabaugh A; Kapoor B; Huang X; Dollings P; Hum WT; Banker A; Wood A; Ellestad G
Biochemistry; 2007 Aug; 46(33):9462-71. PubMed ID: 17649976
[TBL] [Abstract][Full Text] [Related]
31. Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
Cheng XC; Wang Q; Fang H; Tang W; Xu WF
Bioorg Med Chem; 2008 May; 16(10):5398-404. PubMed ID: 18440232
[TBL] [Abstract][Full Text] [Related]
32. Synthesis and evaluation of anti-HIV activity of isatin beta-thiosemicarbazone derivatives.
Bal TR; Anand B; Yogeeswari P; Sriram D
Bioorg Med Chem Lett; 2005 Oct; 15(20):4451-5. PubMed ID: 16115762
[TBL] [Abstract][Full Text] [Related]
33. Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.
Hyatt JL; Moak T; Hatfield MJ; Tsurkan L; Edwards CC; Wierdl M; Danks MK; Wadkins RM; Potter PM
J Med Chem; 2007 Apr; 50(8):1876-85. PubMed ID: 17378546
[TBL] [Abstract][Full Text] [Related]
34. A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury.
Chapman JG; Magee WP; Stukenbrok HA; Beckius GE; Milici AJ; Tracey WR
Eur J Pharmacol; 2002 Dec; 456(1-3):59-68. PubMed ID: 12450570
[TBL] [Abstract][Full Text] [Related]
35. Synthesis and antimicrobial activity of N-Mannich bases of 3-[N'-sulphadoximino] isatin and its methyl derivative.
Surendra ; Pandeya N; Yogeeswari P; Ram DS; Nath G
Boll Chim Farm; 1998 Sep; 137(8):321-4. PubMed ID: 9835147
[TBL] [Abstract][Full Text] [Related]
36. Structural analogues of isatin and their antimicrobial activity.
Maysinger D; Movrin M; Sarić MM
Pharmazie; 1980 Jan; 35(1):14-6. PubMed ID: 7384170
[TBL] [Abstract][Full Text] [Related]
37. Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones.
Kravchenko DV; Kysil VM; Tkachenko SE; Maliarchouk S; Okun IM; Ivachtchenko AV
Eur J Med Chem; 2005 Dec; 40(12):1377-83. PubMed ID: 16169127
[TBL] [Abstract][Full Text] [Related]
38. Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain.
Diaz P; Xu J; Astruc-Diaz F; Pan HM; Brown DL; Naguib M
J Med Chem; 2008 Aug; 51(16):4932-47. PubMed ID: 18666769
[TBL] [Abstract][Full Text] [Related]
39. Identification of potent type I MetAPs inhibitors by simple bioisosteric replacement. Part 2: SAR studies of 5-heteroalkyl substituted TCAT derivatives.
Cui YM; Huang QQ; Xu J; Chen LL; Li JY; Ye QZ; Li J; Nan FJ
Bioorg Med Chem Lett; 2005 Sep; 15(18):4130-5. PubMed ID: 16005224
[TBL] [Abstract][Full Text] [Related]
40. Isatin 1,2,3-triazoles as potent inhibitors against caspase-3.
Jiang Y; Hansen TV
Bioorg Med Chem Lett; 2011 Mar; 21(6):1626-9. PubMed ID: 21324681
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]