254 related articles for article (PubMed ID: 19304954)
1. Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia.
van Rooijen E; Voest EE; Logister I; Korving J; Schwerte T; Schulte-Merker S; Giles RH; van Eeden FJ
Blood; 2009 Jun; 113(25):6449-60. PubMed ID: 19304954
[TBL] [Abstract][Full Text] [Related]
2. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Hickey MM; Lam JC; Bezman NA; Rathmell WK; Simon MC
J Clin Invest; 2007 Dec; 117(12):3879-89. PubMed ID: 17992257
[TBL] [Abstract][Full Text] [Related]
3. A zebrafish model for VHL and hypoxia signaling.
van Rooijen E; Santhakumar K; Logister I; Voest E; Schulte-Merker S; Giles R; van Eeden F
Methods Cell Biol; 2011; 105():163-90. PubMed ID: 21951530
[TBL] [Abstract][Full Text] [Related]
4. Mutations of von Hippel-Lindau tumor-suppressor gene and congenital polycythemia.
Pastore Y; Jedlickova K; Guan Y; Liu E; Fahner J; Hasle H; Prchal JF; Prchal JT
Am J Hum Genet; 2003 Aug; 73(2):412-9. PubMed ID: 12844285
[TBL] [Abstract][Full Text] [Related]
5. Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model.
Metelo AM; Noonan HR; Li X; Jin Y; Baker R; Kamentsky L; Zhang Y; van Rooijen E; Shin J; Carpenter AE; Yeh JR; Peterson RT; Iliopoulos O
J Clin Invest; 2015 May; 125(5):1987-97. PubMed ID: 25866969
[TBL] [Abstract][Full Text] [Related]
6. Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
Russell RC; Sufan RI; Zhou B; Heir P; Bunda S; Sybingco SS; Greer SN; Roche O; Heathcote SA; Chow VW; Boba LM; Richmond TD; Hickey MM; Barber DL; Cheresh DA; Simon MC; Irwin MS; Kim WY; Ohh M
Nat Med; 2011 Jun; 17(7):845-53. PubMed ID: 21685897
[TBL] [Abstract][Full Text] [Related]
7. von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.
van Rooijen E; Voest EE; Logister I; Bussmann J; Korving J; van Eeden FJ; Giles RH; Schulte-Merker S
Dis Model Mech; 2010; 3(5-6):343-53. PubMed ID: 20335444
[TBL] [Abstract][Full Text] [Related]
8. Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology.
Smith TG; Brooks JT; Balanos GM; Lappin TR; Layton DM; Leedham DL; Liu C; Maxwell PH; McMullin MF; McNamara CJ; Percy MJ; Pugh CW; Ratcliffe PJ; Talbot NP; Treacy M; Robbins PA
PLoS Med; 2006 Jul; 3(7):e290. PubMed ID: 16768548
[TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations.
Rathmell WK; Hickey MM; Bezman NA; Chmielecki CA; Carraway NC; Simon MC
Cancer Res; 2004 Dec; 64(23):8595-603. PubMed ID: 15574766
[TBL] [Abstract][Full Text] [Related]
10. The homozygous VHL(D126N) missense mutation is associated with dramatically elevated erythropoietin levels, consequent polycythemia, and early onset severe pulmonary hypertension.
Sarangi S; Lanikova L; Kapralova K; Acharya S; Swierczek S; Lipton JM; Wolfe L; Prchal JT
Pediatr Blood Cancer; 2014 Nov; 61(11):2104-6. PubMed ID: 24729484
[TBL] [Abstract][Full Text] [Related]
11. Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors.
Gordeuk VR; Sergueeva AI; Miasnikova GY; Okhotin D; Voloshin Y; Choyke PL; Butman JA; Jedlickova K; Prchal JT; Polyakova LA
Blood; 2004 May; 103(10):3924-32. PubMed ID: 14726398
[TBL] [Abstract][Full Text] [Related]
12. The HIF pathway and erythrocytosis.
Lee FS; Percy MJ
Annu Rev Pathol; 2011; 6():165-92. PubMed ID: 20939709
[TBL] [Abstract][Full Text] [Related]
13. Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
McClain DA; Abuelgasim KA; Nouraie M; Salomon-Andonie J; Niu X; Miasnikova G; Polyakova LA; Sergueeva A; Okhotin DJ; Cherqaoui R; Okhotin D; Cox JE; Swierczek S; Song J; Simon MC; Huang J; Simcox JA; Yoon D; Prchal JT; Gordeuk VR
J Mol Med (Berl); 2013 Jan; 91(1):59-67. PubMed ID: 23015148
[TBL] [Abstract][Full Text] [Related]
14. The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W).
Tomasic NL; Piterkova L; Huff C; Bilic E; Yoon D; Miasnikova GY; Sergueeva AI; Niu X; Nekhai S; Gordeuk V; Prchal JT
Haematologica; 2013 Apr; 98(4):560-7. PubMed ID: 23403324
[TBL] [Abstract][Full Text] [Related]
15. von Hippel-Lindau gene plays a role during zebrafish pronephros development.
Chen YH; Chang CF; Lai YY; Sun CY; Ding YJ; Tsai JN
In Vitro Cell Dev Biol Anim; 2015 Nov; 51(10):1023-32. PubMed ID: 26194803
[TBL] [Abstract][Full Text] [Related]
16. Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL).
Liu X; Cai X; Hu B; Mei Z; Zhang D; Ouyang G; Wang J; Zhang W; Xiao W
J Biol Chem; 2016 Dec; 291(49):25692-25705. PubMed ID: 27777301
[TBL] [Abstract][Full Text] [Related]
17. Mutations in the VHL gene in sporadic apparently congenital polycythemia.
Pastore YD; Jelinek J; Ang S; Guan Y; Liu E; Jedlickova K; Krishnamurti L; Prchal JT
Blood; 2003 Feb; 101(4):1591-5. PubMed ID: 12393546
[TBL] [Abstract][Full Text] [Related]
18. The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.
Hickey MM; Richardson T; Wang T; Mosqueira M; Arguiri E; Yu H; Yu QC; Solomides CC; Morrisey EE; Khurana TS; Christofidou-Solomidou M; Simon MC
J Clin Invest; 2010 Mar; 120(3):827-39. PubMed ID: 20197624
[TBL] [Abstract][Full Text] [Related]
19. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
20. Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia).
Sable CA; Aliyu ZY; Dham N; Nouraie M; Sachdev V; Sidenko S; Miasnikova GY; Polyakova LA; Sergueeva AI; Okhotin DJ; Bushuev V; Remaley AT; Niu X; Castro OL; Gladwin MT; Kato GJ; Prchal JT; Gordeuk VR
Haematologica; 2012 Feb; 97(2):193-200. PubMed ID: 21993671
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]