268 related articles for article (PubMed ID: 19305425)
1. Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Qin J; Xie Y; Wang B; Hoshino M; Wolff DW; Zhao J; Scofield MA; Dowd FJ; Lin MF; Tu Y
Oncogene; 2009 Apr; 28(16):1853-63. PubMed ID: 19305425
[TBL] [Abstract][Full Text] [Related]
2. The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses.
Kazanietz MG; Barrio-Real L; Casado-Medrano V; Baker MJ; Lopez-Haber C
Small GTPases; 2018 Jul; 9(4):297-303. PubMed ID: 27588611
[TBL] [Abstract][Full Text] [Related]
3. The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
Lucato CM; Halls ML; Ooms LM; Liu HJ; Mitchell CA; Whisstock JC; Ellisdon AM
J Biol Chem; 2015 Aug; 290(34):20827-20840. PubMed ID: 26112412
[TBL] [Abstract][Full Text] [Related]
4. Rac signaling in breast cancer: a tale of GEFs and GAPs.
Wertheimer E; Gutierrez-Uzquiza A; Rosemblit C; Lopez-Haber C; Sosa MS; Kazanietz MG
Cell Signal; 2012 Feb; 24(2):353-362. PubMed ID: 21893191
[TBL] [Abstract][Full Text] [Related]
5. Gbetagamma signaling promotes breast cancer cell migration and invasion.
Kirui JK; Xie Y; Wolff DW; Jiang H; Abel PW; Tu Y
J Pharmacol Exp Ther; 2010 May; 333(2):393-403. PubMed ID: 20110378
[TBL] [Abstract][Full Text] [Related]
6. Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis.
Carretero-Ortega J; Walsh CT; Hernández-García R; Reyes-Cruz G; Brown JH; Vázquez-Prado J
Mol Pharmacol; 2010 Mar; 77(3):435-42. PubMed ID: 20018810
[TBL] [Abstract][Full Text] [Related]
7. P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.
Dillon LM; Bean JR; Yang W; Shee K; Symonds LK; Balko JM; McDonald WH; Liu S; Gonzalez-Angulo AM; Mills GB; Arteaga CL; Miller TW
Oncogene; 2015 Jul; 34(30):3968-76. PubMed ID: 25284585
[TBL] [Abstract][Full Text] [Related]
8. Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.
Montero JC; Seoane S; Pandiella A
Cell Signal; 2013 Nov; 25(11):2281-9. PubMed ID: 23899556
[TBL] [Abstract][Full Text] [Related]
9. Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells.
Wong CY; Wuriyanghan H; Xie Y; Lin MF; Abel PW; Tu Y
J Biol Chem; 2011 Jul; 286(29):25813-22. PubMed ID: 21636851
[TBL] [Abstract][Full Text] [Related]
10. P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
Damoulakis G; Gambardella L; Rossman KL; Lawson CD; Anderson KE; Fukui Y; Welch HC; Der CJ; Stephens LR; Hawkins PT
J Cell Sci; 2014 Jun; 127(Pt 11):2589-600. PubMed ID: 24659802
[TBL] [Abstract][Full Text] [Related]
11. Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
Pan D; Barber MA; Hornigold K; Baker MJ; Toth JM; Oxley D; Welch HC
J Biol Chem; 2016 Mar; 291(12):6359-75. PubMed ID: 26792863
[TBL] [Abstract][Full Text] [Related]
12. P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer.
Montero JC; Seoane S; Ocaña A; Pandiella A
Oncogene; 2011 Mar; 30(9):1059-71. PubMed ID: 21042280
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity.
Mayeenuddin LH; Garrison JC
J Biol Chem; 2006 Jan; 281(4):1921-8. PubMed ID: 16301320
[TBL] [Abstract][Full Text] [Related]
14. Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gα
Cervantes-Villagrana RD; Adame-García SR; García-Jiménez I; Color-Aparicio VM; Beltrán-Navarro YM; König GM; Kostenis E; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
J Biol Chem; 2019 Jan; 294(2):531-546. PubMed ID: 30446620
[TBL] [Abstract][Full Text] [Related]
15. The Rho guanine nucleotide exchange factor P-Rex1 as a potential drug target for cancer metastasis and inflammatory diseases.
Ye RD
Pharmacol Res; 2020 Mar; 153():104676. PubMed ID: 32006571
[TBL] [Abstract][Full Text] [Related]
16. cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits.
Adame-García SR; Cervantes-Villagrana RD; Orduña-Castillo LB; Del Rio JC; Gutkind JS; Reyes-Cruz G; Taylor SS; Vázquez-Prado J
J Biol Chem; 2019 Feb; 294(7):2232-2246. PubMed ID: 30530493
[TBL] [Abstract][Full Text] [Related]
17. P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.
Hernández-Negrete I; Carretero-Ortega J; Rosenfeldt H; Hernández-García R; Calderón-Salinas JV; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
J Biol Chem; 2007 Aug; 282(32):23708-15. PubMed ID: 17565979
[TBL] [Abstract][Full Text] [Related]
18. P-REX1 amplification promotes progression of cutaneous melanoma via the PAK1/P38/MMP-2 pathway.
Wang J; Hirose H; Du G; Chong K; Kiyohara E; Witz IP; Hoon DSB
Cancer Lett; 2017 Oct; 407():66-75. PubMed ID: 28803992
[TBL] [Abstract][Full Text] [Related]
19. Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function.
Zhao T; Nalbant P; Hoshino M; Dong X; Wu D; Bokoch GM
J Leukoc Biol; 2007 Apr; 81(4):1127-36. PubMed ID: 17227822
[TBL] [Abstract][Full Text] [Related]
20. Involvement of a Rac activator,P-Rex1, in neurotrophin-derived signaling and neuronal migration.
Yoshizawa M; Kawauchi T; Sone M; Nishimura YV; Terao M; Chihama K; Nabeshima Y; Hoshino M
J Neurosci; 2005 Apr; 25(17):4406-19. PubMed ID: 15858067
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
